Protein: CCL3
C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))]

Gene: CCL3
Organism: Homo sapiens
Interactions: 178
UniProt ID: P10147

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001649 - osteoblast differentiation
GO:0001775 - cell activation
GO:0002548 - monocyte chemotaxis
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

486230

CCR1
C-C chemokine receptor type 1

13

20

Small-scale

0.972

High

486239

CCR5
C-C chemokine receptor type 5

6

20

Small-scale

0.933

High

486214

CCL3
C-C motif chemokine 3

2

19

Small-scale

0.812

High

486231

CXCR5
C-X-C chemokine receptor type 5

2

20

Small-scale

0.754

High

486218

CSPG2
Versican core protein

1

10

High-throughput

0.691

High

486313

HPLN3
Hyaluronan and proteoglycan link protein 3

1

11

High-throughput

0.691

High

486238

CCR4
C-C chemokine receptor type 4

1

20

Small-scale

0.647

High

134354

ACKR2
Atypical chemokine receptor 2

1

20

Small-scale

0.618

High

486216

CCL4
C-C motif chemokine 4

1

20

Small-scale

0.618

High

486237

CCR3
C-C chemokine receptor type 3

1

20

Small-scale

0.618

High

486343

UBQL2
Ubiquilin-2

2

5

High-throughput

0.606

High

486351

UBQL1
Ubiquilin-1

2

5

High-throughput

0.606

High

486219

IDE
Insulin-degrading enzyme

1

4

Small-scale

0.586

High

126505

QSOX1
Sulfhydryl oxidase 1

1

2

High-throughput

0.536

High

129662

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

9

High-throughput

0.536

High

172638

LAMA5
Laminin subunit alpha-5

1

10

High-throughput

0.536

High

203018

COCH
Cochlin

1

3

High-throughput

0.536

High

234417

NRP2
Neuropilin-2

1

5

High-throughput

0.536

High

236282

B4GT3
Beta-1,4-galactosyltransferase 3

1

5

High-throughput

0.536

High

236352

B4GT4
Beta-1,4-galactosyltransferase 4

1

5

High-throughput

0.536

High

245779

CATL2
Cathepsin L2

1

1

High-throughput

0.536

High

296636

SLIT2
Slit homolog 2 protein

1

4

High-throughput

0.536

High

312842

GDF11
Growth/differentiation factor 11

1

3

High-throughput

0.536

High

314537

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

4

High-throughput

0.536

High

314809

LARG1
Xylosyl- and glucuronyltransferase LARGE1

1

1

High-throughput

0.536

High

317783

NET1
Netrin-1

1

8

High-throughput

0.536

High

324725

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

2

High-throughput

0.536

High

421252

GDN
Glia-derived nexin

1

1

High-throughput

0.536

High

433113

LAMB1
Laminin subunit beta-1

1

8

High-throughput

0.536

High

486215

LAMC1
Laminin subunit gamma-1

1

7

High-throughput

0.536

High

486217

BMP1
Bone morphogenetic protein 1

1

3

High-throughput

0.536

High

486220

B4GT1
Beta-1,4-galactosyltransferase 1

1

5

High-throughput

0.536

High

486221

ARSB
Arylsulfatase B

1

5

High-throughput

0.536

High

486224

VGFR1
Vascular endothelial growth factor receptor 1

1

3

High-throughput

0.536

High

486227

LAMA1
Laminin subunit alpha-1

1

8

High-throughput

0.536

High

486232

GALNS
N-acetylgalactosamine-6-sulfatase

1

5

High-throughput

0.536

High

486233

TIMP3
Metalloproteinase inhibitor 3

1

1

High-throughput

0.536

High

486234

PEDF
Pigment epithelium-derived factor

1

1

High-throughput

0.536

High

486235

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

4

High-throughput

0.536

High

486236

MMP15
Matrix metalloproteinase-15

1

5

High-throughput

0.536

High

486240

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

2

High-throughput

0.536

High

486243

LAMB2
Laminin subunit beta-2

1

8

High-throughput

0.536

High

486244

NETR
Neurotrypsin

1

1

High-throughput

0.536

High

486245

INHBE
Inhibin beta E chain

1

3

High-throughput

0.536

High

486248

CNTP1
Contactin-associated protein 1

1

13

High-throughput

0.536

High

486253

MFGM
Lactadherin

1

4

High-throughput

0.536

High

486255

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

4

High-throughput

0.536

High

486258

MAP7
Ensconsin

1

2

High-throughput

0.536

High

486261

ICAM4
Intercellular adhesion molecule 4

1

2

High-throughput

0.536

High

486262

PGFRL
Platelet-derived growth factor receptor-like protein

1

3

High-throughput

0.536

High

486264

LAMA4
Laminin subunit alpha-4

1

15

High-throughput

0.536

High

486267

LRC24
Leucine-rich repeat-containing protein 24

1

4

High-throughput

0.536

High

486273

METRL
Meteorin-like protein

1

1

High-throughput

0.536

High

486278

LARP4
La-related protein 4

1

1

High-throughput

0.536

High

486283

CHSS1
Chondroitin sulfate synthase 1

1

7

High-throughput

0.536

High

486285

CILP2
Cartilage intermediate layer protein 2

1

6

High-throughput

0.536

High

486287

SULF2
Extracellular sulfatase Sulf-2

1

5

High-throughput

0.536

High

486288

SULF1
Extracellular sulfatase Sulf-1

1

5

High-throughput

0.536

High

486296

NDNF
Protein NDNF

1

1

High-throughput

0.536

High

486297

ATS17
A disintegrin and metalloproteinase with thrombospondin motifs 17

1

4

High-throughput

0.536

High

486298

ATS15
A disintegrin and metalloproteinase with thrombospondin motifs 15

1

4

High-throughput

0.536

High

486301

LAR4B
La-related protein 4B

1

1

High-throughput

0.536

High

486303

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

2

High-throughput

0.536

High

486306

TRI11
E3 ubiquitin-protein ligase TRIM11

1

1

High-throughput

0.536

High

486307

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

3

High-throughput

0.536

High

486312

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.536

High

486315

PKP4
Plakophilin-4

1

2

High-throughput

0.536

High

486316

PKP2
Plakophilin-2

1

3

High-throughput

0.536

High

486317

SEM3C
Semaphorin-3C

1

1

High-throughput

0.536

High

486320

EMIL2
EMILIN-2

1

4

High-throughput

0.536

High

486325

CRLD1
Cysteine-rich secretory protein LCCL domain-containing 1

1

1

High-throughput

0.536

High

486333

EMIL3
EMILIN-3

1

10

High-throughput

0.536

High

486337

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

1

High-throughput

0.536

High

486340

EXTL2
Exostosin-like 2

1

2

High-throughput

0.536

High

486344

EGFL7
Epidermal growth factor-like protein 7

1

9

High-throughput

0.536

High

486345

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

4

High-throughput

0.536

High

486347

METRN
Meteorin

1

1

High-throughput

0.536

High

486348

TNIK
TRAF2 and NCK-interacting protein kinase

1

2

High-throughput

0.536

High

486349

PCOC2
Procollagen C-endopeptidase enhancer 2

1

8

High-throughput

0.536

High

64646

RHG32
Rho GTPase-activating protein 32

1

0

High-throughput

0.513

High

309653

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.513

High

316470

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.513

High

413022

CHLE
Cholinesterase

1

0

High-throughput

0.513

High

436971

DAF
Complement decay-accelerating factor

1

0

High-throughput

0.513

High

441049

CO4A2

1

0

High-throughput

0.513

High

445934

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.513

High

486226

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

High-throughput

0.513

High

486229

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

0

High-throughput

0.513

High

486241

EPHB4
Ephrin type-B receptor 4

1

0

High-throughput

0.513

High

486242

PLTP
Phospholipid transfer protein

1

0

High-throughput

0.513

High

486247

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

486252

LOXL1
Lysyl oxidase homolog 1

1

0

High-throughput

0.513

High

486254

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.513

High

486256

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

High-throughput

0.513

High

486257

DAG1
Dystroglycan 1

1

0

High-throughput

0.513

High

486260

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

0

High-throughput

0.513

High

486266

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.513

High

486271

ANGE2
Protein angel homolog 2

1

0

High-throughput

0.513

High

486275

ABH15
Protein ABHD15

1

0

High-throughput

0.513

High

486279

MON1B
Vacuolar fusion protein MON1 homolog B

1

0

High-throughput

0.513

High

486281

FJX1
Four-jointed box protein 1

1

0

High-throughput

0.513

High

486284

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.513

High

486293

PCYXL
Prenylcysteine oxidase-like

1

0

High-throughput

0.513

High

486295

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.513

High

486302

PXDN
Peroxidasin homolog

1

0

High-throughput

0.513

High

486311

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.513

High

486314

STRBP
Spermatid perinuclear RNA-binding protein

1

0

High-throughput

0.513

High

486318

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.513

High

486319

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.513

High

486323

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.513

High

486324

XYLT2
Xylosyltransferase 2

1

0

High-throughput

0.513

High

486327

FKRP
Ribitol 5-phosphate transferase FKRP

1

0

High-throughput

0.513

High

486330

VEZA
Vezatin

1

0

High-throughput

0.513

High

486334

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.513

High

486346

CEIP2
Inactive cell surface hyaluronidase CEMIP2

1

0

High-throughput

0.513

High

486352

HPSE
Heparanase

1

0

High-throughput

0.513

High

486354

NDK7
Nucleoside diphosphate kinase homolog 7

1

0

High-throughput

0.513

High

427032

CATD
Cathepsin D

1

3

Small-scale

0.501

High

172347

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.489

High

199574

B4GT5
Beta-1,4-galactosyltransferase 5

1

5

High-throughput

0.489

High

216375

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

1

9

High-throughput

0.489

High

267735

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

2

High-throughput

0.489

High

315457

G6PE
GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase

1

1

High-throughput

0.489

High

486259

PDIA5
Protein disulfide-isomerase A5

1

3

High-throughput

0.489

High

486265

EXT1
Exostosin-1

1

2

High-throughput

0.489

High

486268

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

1

High-throughput

0.489

High

486269

DNLZ
DNL-type zinc finger protein

1

1

High-throughput

0.489

High

486272

CAHD1
VWFA and cache domain-containing protein 1

1

1

High-throughput

0.489

High

486274

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

4

High-throughput

0.489

High

486276

B3GLT
Beta-1,3-glucosyltransferase

1

6

High-throughput

0.489

High

486277

CHSS3
Chondroitin sulfate synthase 3

1

7

High-throughput

0.489

High

486280

GALT7
N-acetylgalactosaminyltransferase 7

1

4

High-throughput

0.489

High

486282

AMZ2
Archaemetzincin-2

1

4

High-throughput

0.489

High

486290

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

1

High-throughput

0.489

High

486291

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

1

4

High-throughput

0.489

High

486294

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

4

High-throughput

0.489

High

486310

C2AIL
CDKN2AIP N-terminal-like protein

1

1

High-throughput

0.489

High

486331

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

6

High-throughput

0.489

High

486335

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.489

High

486336

CARF
CDKN2A-interacting protein

1

2

High-throughput

0.489

High

486338

CHPF2
Chondroitin sulfate glucuronyltransferase

1

7

High-throughput

0.489

High

486341

B4GT7
Beta-1,4-galactosyltransferase 7

1

5

High-throughput

0.489

High

486342

B4GT6
Beta-1,4-galactosyltransferase 6

1

5

High-throughput

0.489

High

486353

HS3S2
Heparan sulfate glucosamine 3-O-sulfotransferase 2

1

2

High-throughput

0.489

High

486355

HS3SB
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

1

2

High-throughput

0.489

High

486223

CEBPB
CCAAT/enhancer-binding protein beta

1

5

Small-scale

0.479

High

486246

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

486222

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

Small-scale

0.437

High

61114

KRBA1
Protein KRBA1

1

0

High-throughput

0.279

Low

225290

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

266469

SUPT3
Transcription initiation protein SPT3 homolog

1

0

High-throughput

0.279

Low

300659

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

304522

PRS23
Serine protease 23

1

0

High-throughput

0.279

Low

486225

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.279

Low

486228

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.279

Low

486249

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

486251

FOXM1
Forkhead box protein M1

1

0

High-throughput

0.279

Low

486263

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.279

Low

486270

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

1

0

High-throughput

0.279

Low

486286

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.279

Low

486289

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.279

Low

486292

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

486299

PXYP1
2-phosphoxylose phosphatase 1

1

0

High-throughput

0.279

Low

486300

PHF3
PHD finger protein 3

1

0

High-throughput

0.279

Low

486304

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.279

Low

486305

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

486308

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.279

Low

486309

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

486321

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

486322

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.279

Low

486326

OFUT1
GDP-fucose protein O-fucosyltransferase 1

1

0

High-throughput

0.279

Low

486328

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

0

High-throughput

0.279

Low

486329

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

486332

CHST7
Carbohydrate sulfotransferase 7

1

0

High-throughput

0.279

Low

486339

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.279

Low

486350

PPT2
Lysosomal thioesterase PPT2

1

0

High-throughput

0.279

Low

486250

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.269

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024