Protein: EF2K
Eukaryotic elongation factor 2 kinase (eEF-2 kinase) (eEF-2K) (EC 2.7.11.20) (Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase)

Gene: EF2K, EEF2K
Organism: Homo sapiens
Interactions: 39
UniProt ID: O00418

Gene Ontology (top 5):
GO:0002931 - response to ischemia
GO:0004672 - protein kinase activity
GO:0004686 - elongation factor-2 kinase activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

127651

FBW1B
F-box/WD repeat-containing protein 11

7

1

Small-scale

0.742

High

127653

FBW1A
F-box/WD repeat-containing protein 1A

4

1

Small-scale

0.702

High

127620

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

3

1

High-throughput

0.667

High

127626

EPB41
Protein 4.1

2

3

High-throughput

0.628

High

127648

E41L1
Band 4.1-like protein 1

2

3

High-throughput

0.628

High

127654

E41L3
Band 4.1-like protein 3

2

3

High-throughput

0.628

High

127647

HS12B
Heat shock 70 kDa protein 12B

2

0

High-throughput

0.595

High

127623

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.586

High

127627

EF2
Elongation factor 2

2

0

Small-scale

0.577

High

127642

KS6A1
Ribosomal protein S6 kinase alpha-1

1

2

Small-scale

0.536

High

61254

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.513

High

127625

RET1
Retinol-binding protein 1

1

0

High-throughput

0.513

High

127631

SPR1B
Cornifin-B

1

0

High-throughput

0.513

High

127633

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

127635

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.513

High

127638

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

127640

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.513

High

127641

ACACA
Acetyl-CoA carboxylase 1

1

0

High-throughput

0.513

High

127645

WDFY3
WD repeat and FYVE domain-containing protein 3

1

0

High-throughput

0.513

High

127632

KS6B1
Ribosomal protein S6 kinase beta-1

1

2

Small-scale

0.501

High

127630

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

2

High-throughput

0.489

High

127617

XPO1
Exportin-1

1

3

High-throughput

0.479

High

127629

EZRI
Ezrin

1

3

High-throughput

0.479

High

127634

IF4A3
Eukaryotic initiation factor 4A-III

1

3

Small-scale

0.479

High

127637

MAP2
Methionine aminopeptidase 2

1

1

Small-scale

0.479

High

127643

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

127646

BICD1
Protein bicaudal D homolog 1

1

7

High-throughput

0.479

High

127649

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.479

High

127652

PA2G4
Proliferation-associated protein 2G4

1

1

Small-scale

0.479

High

127622

ALBU
Albumin

1

0

Small-scale

0.458

High

127624

PROF1
Profilin-1

1

0

High-throughput

0.458

High

127639

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.458

High

127644

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

127628

CCNB1
G2/mitotic-specific cyclin-B1

1

0

Small-scale

0.426

High

127650

KS6B2
Ribosomal protein S6 kinase beta-2

1

2

Small-scale

0.408

High

127619

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.279

Low

127636

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

Small-scale

0.279

Low

127618

DENR
Density-regulated protein

1

0

Small-scale

0.249

Low

127621

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024