Protein: RU2B
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')

Gene: RU2B, SNRPB2
Organism: Homo sapiens
Interactions: 238
UniProt ID: P08579

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0001650 - fibrillar center
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

441217

RU2A
U2 small nuclear ribonucleoprotein A'

7

10

Small-scale

0.967

High

441212

RU17
U1 small nuclear ribonucleoprotein 70 kDa

4

20

High-throughput

0.903

High

441294

SF3A2
Splicing factor 3A subunit 2

4

8

Small-scale

0.895

High

441271

SF3A3
Splicing factor 3A subunit 3

3

4

High-throughput

0.861

High

212094

HTSF1
17S U2 SnRNP complex component HTATSF1

2

20

High-throughput

0.811

High

268580

SF3B1
Splicing factor 3B subunit 1

2

5

High-throughput

0.811

High

441274

SF3B2
Splicing factor 3B subunit 2

2

4

High-throughput

0.811

High

441292

SF3B3
Splicing factor 3B subunit 3

2

4

High-throughput

0.811

High

441293

SF3B4
Splicing factor 3B subunit 4

2

20

High-throughput

0.811

High

441349

SPF45
Splicing factor 45

2

20

High-throughput

0.811

High

441380

RBM22
Pre-mRNA-splicing factor RBM22

2

19

High-throughput

0.811

High

441397

SF3B6
Splicing factor 3B subunit 6

2

19

High-throughput

0.811

High

441283

RBM39
RNA-binding protein 39

2

20

High-throughput

0.789

High

441392

ZN346
Zinc finger protein 346

2

4

High-throughput

0.789

High

441303

LARP7
La-related protein 7

2

20

High-throughput

0.754

High

127700

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.691

High

165379

SR140
U2 snRNP-associated SURP motif-containing protein

1

17

High-throughput

0.691

High

213884

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

20

High-throughput

0.691

High

441214

SNRPA
U1 small nuclear ribonucleoprotein A

1

19

High-throughput

0.691

High

441235

FUS
RNA-binding protein FUS

1

20

High-throughput

0.691

High

441241

KC1A
Casein kinase I isoform alpha

1

8

High-throughput

0.691

High

441245

RBM25
RNA-binding protein 25

1

9

High-throughput

0.691

High

441280

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

2

High-throughput

0.691

High

441287

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

1

20

High-throughput

0.691

High

441324

THOC4
THO complex subunit 4

1

18

High-throughput

0.691

High

441347

TOE1
Target of EGR1 protein 1

1

3

High-throughput

0.691

High

441350

RNPC3
RNA-binding region-containing protein 3

1

19

High-throughput

0.691

High

441391

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

12

High-throughput

0.691

High

441393

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

6

High-throughput

0.691

High

441401

RBM8A
RNA-binding protein 8A

1

20

High-throughput

0.691

High

441259

SMD3
Small nuclear ribonucleoprotein Sm D3

4

16

High-throughput

0.691

High

215867

ZBT14
Zinc finger and BTB domain-containing protein 14

3

3

High-throughput

0.675

High

441224

TRI27
Zinc finger protein RFP

3

5

High-throughput

0.675

High

441254

RUXE
Small nuclear ribonucleoprotein E

3

4

High-throughput

0.675

High

441255

RUXF
Small nuclear ribonucleoprotein F

3

15

High-throughput

0.675

High

441225

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

8

High-throughput

0.667

High

441262

RSMN
Small nuclear ribonucleoprotein-associated protein N

3

10

High-throughput

0.667

High

441295

SF3A1
Splicing factor 3A subunit 1

3

8

High-throughput

0.667

High

441345

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

3

16

High-throughput

0.662

High

441329

SUGP1
SURP and G-patch domain-containing protein 1

2

9

High-throughput

0.636

High

441331

HOMEZ
Homeobox and leucine zipper protein Homez

2

7

High-throughput

0.633

High

441237

COIL
Coilin

2

1

High-throughput

0.628

High

441257

SMD1
Small nuclear ribonucleoprotein Sm D1

2

15

High-throughput

0.628

High

441258

SMD2
Small nuclear ribonucleoprotein Sm D2

2

3

High-throughput

0.628

High

441276

SNW1
SNW domain-containing protein 1

2

6

High-throughput

0.628

High

441323

PHF5A
PHD finger-like domain-containing protein 5A

2

3

High-throughput

0.628

High

441337

GEMI5
Gem-associated protein 5

2

11

High-throughput

0.628

High

441355

CDC5L
Cell division cycle 5-like protein

2

8

High-throughput

0.628

High

441361

SF3B5
Splicing factor 3B subunit 5

2

2

High-throughput

0.628

High

441362

NADAP
Kanadaptin

2

4

High-throughput

0.628

High

441365

CRNL1
Crooked neck-like protein 1

2

20

High-throughput

0.628

High

441315

MAST2
Microtubule-associated serine/threonine-protein kinase 2

1

9

High-throughput

0.618

High

162347

XPO1
Exportin-1

1

12

High-throughput

0.618

High

373552

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.618

High

441233

PDIA3
Protein disulfide-isomerase A3

1

1

High-throughput

0.618

High

441246

CDK7
Cyclin-dependent kinase 7

1

10

High-throughput

0.618

High

441264

EWS
RNA-binding protein EWS

1

20

High-throughput

0.618

High

441281

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

5

High-throughput

0.618

High

441291

RNPS1
RNA-binding protein with serine-rich domain 1

1

20

High-throughput

0.618

High

441299

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

18

High-throughput

0.618

High

441318

LN28B
Protein lin-28 homolog B

1

20

High-throughput

0.618

High

441341

RBP56
TATA-binding protein-associated factor 2N

1

20

High-throughput

0.618

High

441373

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.618

High

441390

TNIK
TRAF2 and NCK-interacting protein kinase

1

7

High-throughput

0.618

High

278718

DNJC8
DnaJ homolog subfamily C member 8

2

3

High-throughput

0.611

High

441256

RUXG
Small nuclear ribonucleoprotein G

2

20

High-throughput

0.611

High

441279

DX39B
Spliceosome RNA helicase DDX39B

2

20

High-throughput

0.611

High

441289

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

8

High-throughput

0.611

High

441325

ZCH18
Zinc finger CCCH domain-containing protein 18

2

19

High-throughput

0.611

High

441382

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

2

0

High-throughput

0.608

High

441236

TRI23
E3 ubiquitin-protein ligase TRIM23

2

3

High-throughput

0.606

High

441336

GABP2
GA-binding protein subunit beta-2

2

7

High-throughput

0.606

High

441335

PNMA1
Paraneoplastic antigen Ma1

2

5

High-throughput

0.594

High

441332

SRRM1
Serine/arginine repetitive matrix protein 1

2

16

High-throughput

0.584

High

441222

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

2

0

High-throughput

0.580

High

441351

NP1L5
Nucleosome assembly protein 1-like 5

2

0

High-throughput

0.580

High

441268

NCBP1
Nuclear cap-binding protein subunit 1

1

7

High-throughput

0.575

High

441296

SF01
Splicing factor 1

1

18

High-throughput

0.575

High

441266

GABP1
GA-binding protein subunit beta-1

1

7

High-throughput

0.573

High

441285

MCM6
DNA replication licensing factor MCM6

1

6

High-throughput

0.573

High

441307

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

6

High-throughput

0.573

High

441314

HMBX1
Homeobox-containing protein 1

1

1

High-throughput

0.573

High

148305

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.553

High

441270

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

8

High-throughput

0.553

High

441327

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

7

High-throughput

0.553

High

199647

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.536

High

202360

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

2

High-throughput

0.536

High

209381

PLRG1
Pleiotropic regulator 1

1

17

High-throughput

0.536

High

230705

AQR
RNA helicase aquarius

1

17

High-throughput

0.536

High

236186

PRP17
Pre-mRNA-processing factor 17

1

18

High-throughput

0.536

High

256446

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

5

High-throughput

0.536

High

263477

PR40A
Pre-mRNA-processing factor 40 homolog A

1

20

High-throughput

0.536

High

272011

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

20

High-throughput

0.536

High

278376

SPF27
Pre-mRNA-splicing factor SPF27

1

2

High-throughput

0.536

High

300033

PRP6
Pre-mRNA-processing factor 6

1

18

High-throughput

0.536

High

441215

RU1C
U1 small nuclear ribonucleoprotein C

1

5

High-throughput

0.536

High

441227

H2AX
Histone H2AX

1

8

High-throughput

0.536

High

441231

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.536

High

441238

IF4A3
Eukaryotic initiation factor 4A-III

1

20

High-throughput

0.536

High

441249

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.536

High

441250

GEMI4
Gem-associated protein 4

1

3

High-throughput

0.536

High

441263

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.536

High

441277

CUL1
Cullin-1

1

20

High-throughput

0.536

High

441278

CUL3
Cullin-3

1

20

High-throughput

0.536

High

441284

DHX8
ATP-dependent RNA helicase DHX8

1

9

High-throughput

0.536

High

441286

FL2D
Pre-mRNA-splicing regulator WTAP

1

1

High-throughput

0.536

High

441297

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.536

High

441300

SMN
Survival motor neuron protein

1

5

High-throughput

0.536

High

441301

C19L2
CWF19-like protein 2

1

3

High-throughput

0.536

High

441305

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

9

High-throughput

0.536

High

441311

ICE2
Little elongation complex subunit 2

1

1

High-throughput

0.536

High

441312

C19L1
CWF19-like protein 1

1

3

High-throughput

0.536

High

441316

PRP8
Pre-mRNA-processing-splicing factor 8

1

5

High-throughput

0.536

High

441326

DDX42
ATP-dependent RNA helicase DDX42

1

12

High-throughput

0.536

High

441328

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

10

High-throughput

0.536

High

441330

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

4

High-throughput

0.536

High

441333

PDCD7
Programmed cell death protein 7

1

1

High-throughput

0.536

High

441338

CCD12
Coiled-coil domain-containing protein 12

1

2

High-throughput

0.536

High

441343

CUL5
Cullin-5

1

20

High-throughput

0.536

High

441353

TGS1
Trimethylguanosine synthase

1

1

High-throughput

0.536

High

441360

DDX23
Probable ATP-dependent RNA helicase DDX23

1

17

High-throughput

0.536

High

441363

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.536

High

441366

SKI8
Superkiller complex protein 8

1

15

High-throughput

0.536

High

441367

NSRP1
Nuclear speckle splicing regulatory protein 1

1

4

High-throughput

0.536

High

441369

PININ
Pinin

1

3

High-throughput

0.536

High

441371

PHAX
Phosphorylated adapter RNA export protein

1

2

High-throughput

0.536

High

441374

PKHA2
Pleckstrin homology domain-containing family A member 2

1

4

High-throughput

0.536

High

441375

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

4

High-throughput

0.536

High

441376

SYF1
Pre-mRNA-splicing factor SYF1

1

20

High-throughput

0.536

High

441385

KLHL8
Kelch-like protein 8

1

1

High-throughput

0.536

High

441389

DDX20
Probable ATP-dependent RNA helicase DDX20

1

20

High-throughput

0.536

High

441396

TR150
Thyroid hormone receptor-associated protein 3

1

10

High-throughput

0.536

High

441398

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

15

High-throughput

0.536

High

441229

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

6

High-throughput

0.526

High

441267

GOGA2
Golgin subfamily A member 2

1

6

High-throughput

0.523

High

441384

RHG23
Rho GTPase-activating protein 23

2

5

High-throughput

0.521

High

330820

PAK4
Serine/threonine-protein kinase PAK 4

1

8

High-throughput

0.514

High

441308

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.514

High

441320

NEK10
Serine/threonine-protein kinase Nek10

1

9

High-throughput

0.514

High

305059

SPN1
Snurportin-1

1

0

High-throughput

0.513

High

441313

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.513

High

441339

PCNP
PEST proteolytic signal-containing nuclear protein

1

0

High-throughput

0.513

High

441346

CCD97
Coiled-coil domain-containing protein 97

1

0

High-throughput

0.513

High

441372

PKRI1
PRKR-interacting protein 1

1

0

High-throughput

0.513

High

441395

ICE1
Little elongation complex subunit 1

1

0

High-throughput

0.513

High

441359

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

13

High-throughput

0.508

High

441251

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.501

High

157409

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

20

High-throughput

0.489

High

441218

IFIT2
Interferon-induced protein with tetratricopeptide repeats 2

1

20

High-throughput

0.489

High

441219

IFIT1
Interferon-induced protein with tetratricopeptide repeats 1

1

20

High-throughput

0.489

High

441317

TTC33
Tetratricopeptide repeat protein 33

1

10

High-throughput

0.489

High

125102

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

High-throughput

0.479

High

167658

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

17

High-throughput

0.479

High

209601

PRC1
Protein regulator of cytokinesis 1

1

10

High-throughput

0.479

High

210438

ZN207
BUB3-interacting and GLEBS motif-containing protein ZNF207

1

2

High-throughput

0.479

High

214043

SPOP
Speckle-type POZ protein

1

3

High-throughput

0.479

High

233155

NUPR1
Nuclear protein 1

1

4

High-throughput

0.479

High

254862

CPNE3
Copine-3

1

5

High-throughput

0.479

High

294283

RECQ4
ATP-dependent DNA helicase Q4

1

16

High-throughput

0.479

High

308335

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

313209

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

2

High-throughput

0.479

High

326387

SNAI1
Zinc finger protein SNAI1

1

8

High-throughput

0.479

High

345734

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

378925

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

441216

F16P1
Fructose-1,6-bisphosphatase 1

1

3

High-throughput

0.479

High

441221

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

441226

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.479

High

441228

CEBPB
CCAAT/enhancer-binding protein beta

1

12

High-throughput

0.479

High

441230

CRCM
Colorectal mutant cancer protein

1

3

High-throughput

0.479

High

441232

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

441234

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.479

High

441239

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

441240

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.479

High

441243

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

441247

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

8

High-throughput

0.479

High

441252

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

1

High-throughput

0.479

High

441253

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

441260

H4
Histone H4

1

4

High-throughput

0.479

High

441261

RS25
Small ribosomal subunit protein eS25

1

1

High-throughput

0.479

High

441265

PO5F1
POU domain, class 5, transcription factor 1

1

3

High-throughput

0.479

High

441269

EP300
Histone acetyltransferase p300

1

9

High-throughput

0.479

High

441272

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.479

High

441273

RFA4
Replication protein A 30 kDa subunit

1

11

High-throughput

0.479

High

441275

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

441288

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

441290

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

441298

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

441321

SND1
Staphylococcal nuclease domain-containing protein 1

1

6

High-throughput

0.479

High

441322

MEPCE
7SK snRNA methylphosphate capping enzyme

1

5

High-throughput

0.479

High

441340

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

441342

CSN5
COP9 signalosome complex subunit 5

1

8

High-throughput

0.479

High

441352

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

2

High-throughput

0.479

High

441356

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

441357

ANM1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.479

High

441358

RIOK1
Serine/threonine-protein kinase RIO1

1

7

High-throughput

0.479

High

441364

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.479

High

441368

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

441388

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

441394

PA2G4
Proliferation-associated protein 2G4

1

4

High-throughput

0.479

High

441399

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

15

High-throughput

0.479

High

441400

MAFB
Transcription factor MafB

1

9

High-throughput

0.479

High

441302

MA7D1
MAP7 domain-containing protein 1

1

6

High-throughput

0.470

High

262677

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

296689

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.458

High

441344

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

441354

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

441379

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.458

High

68394

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

20

High-throughput

0.445

High

69420

A9Z1X7
Serine and arginine repetitive matrix 1

1

11

High-throughput

0.445

High

195321

DHX15
ATP-dependent RNA helicase DHX15

1

9

High-throughput

0.445

High

401285

JUN
Transcription factor Jun

1

11

High-throughput

0.445

High

441220

TAU
Microtubule-associated protein tau

1

19

High-throughput

0.445

High

441304

NCBP3
Nuclear cap-binding protein subunit 3

1

6

High-throughput

0.445

High

441306

ODFP2
Outer dense fiber protein 2

1

6

High-throughput

0.445

High

255444

OBSL1
Obscurin-like protein 1

1

8

High-throughput

0.437

High

354255

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.437

High

417669

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.437

High

441213

ANXA5
Annexin A5

1

3

High-throughput

0.437

High

441223

PLST
Plastin-3

1

5

High-throughput

0.437

High

441282

GRM2
Metabotropic glutamate receptor 2

1

2

High-throughput

0.437

High

441310

RC3H1
Roquin-1

1

13

High-throughput

0.437

High

441319

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

441348

DDRGK
DDRGK domain-containing protein 1

1

6

High-throughput

0.437

High

441370

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

441377

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

5

High-throughput

0.437

High

441383

ITSN2
Intersectin-2

1

2

High-throughput

0.437

High

441386

HECW2
E3 ubiquitin-protein ligase HECW2

1

9

High-throughput

0.437

High

441244

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.408

High

61731

A6H8W8
Intersectin 2

1

2

High-throughput

0.407

High

441309

CE170
Centrosomal protein of 170 kDa

1

11

High-throughput

0.407

High

441334

GPT11
G patch domain-containing protein 11

2

0

High-throughput

0.328

High

441378

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

441381

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

2

0

High-throughput

0.316

High

242654

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.249

Low

417475

PYGL
Glycogen phosphorylase, liver form

1

0

High-throughput

0.249

Low

441242

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.249

Low

441248

RM12
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

441387

CRNN
Cornulin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024