Protein: CYTA
Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed]

Gene: CYTA, CSTA
Organism: Homo sapiens
Interactions: 147
UniProt ID: P01040

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0002020 - protease binding
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

345045

CATB
Cathepsin B

4

7

Small-scale

0.896

High

345044

CATL1
Procathepsin L

3

6

Small-scale

0.857

High

345047

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

2

6

Small-scale

0.776

High

245771

CATL2
Cathepsin L2

1

4

High-throughput

0.691

High

345062

CATO
Cathepsin O

1

8

High-throughput

0.691

High

345065

CATC
Dipeptidyl peptidase 1

1

9

High-throughput

0.691

High

345149

CATF
Cathepsin F

1

8

High-throughput

0.691

High

345130

LGMN
Legumain

1

1

Small-scale

0.647

High

345033

CYTA
Cystatin-A

1

0

Small-scale

0.614

High

345048

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.611

High

345079

CUL2
Cullin-2

2

2

High-throughput

0.611

High

345087

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.602

High

345071

RHG04
Rho GTPase-activating protein 4

2

1

High-throughput

0.571

High

345129

PKH4B
Pleckstrin homology domain-containing family G member 4B

2

1

High-throughput

0.571

High

345136

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

4

High-throughput

0.571

High

345051

DESP
Desmoplakin

2

0

Small-scale

0.569

High

62124

RCCD1
RCC1 domain-containing protein 1

1

1

High-throughput

0.536

High

63627

RASFA
Ras association domain-containing protein 10

1

1

High-throughput

0.536

High

208026

HAIR
Lysine-specific demethylase hairless

1

1

High-throughput

0.536

High

256929

KDM4A
Lysine-specific demethylase 4A

1

1

High-throughput

0.536

High

277396

RASF9
Ras association domain-containing protein 9

1

1

High-throughput

0.536

High

345080

CUL4B
Cullin-4B

1

2

High-throughput

0.536

High

345101

KDM3B
Lysine-specific demethylase 3B

1

1

High-throughput

0.536

High

345112

HORN
Hornerin

1

2

High-throughput

0.536

High

345121

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

1

High-throughput

0.536

High

345139

KDM4C
Lysine-specific demethylase 4C

1

1

High-throughput

0.536

High

345145

ASF1B
Histone chaperone ASF1B

1

1

High-throughput

0.536

High

345150

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

1

High-throughput

0.536

High

345153

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.536

High

345117

ARG39
Rho guanine nucleotide exchange factor 39

2

2

High-throughput

0.521

High

345104

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

128692

RTCA
RNA 3'-terminal phosphate cyclase

1

0

High-throughput

0.513

High

158719

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.513

High

174527

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.513

High

238521

ANM3
Protein arginine N-methyltransferase 3

1

0

High-throughput

0.513

High

329065

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

337720

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.513

High

345060

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

345063

NASP
Nuclear autoantigenic sperm protein

1

0

High-throughput

0.513

High

345075

RAD51
DNA repair protein RAD51 homolog 1

1

0

High-throughput

0.513

High

345082

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

High-throughput

0.513

High

345086

OASL
2'-5'-oligoadenylate synthase-like protein

1

0

High-throughput

0.513

High

345094

CYTSA
Cytospin-A

1

0

High-throughput

0.513

High

345097

FOXR1
Forkhead box protein R1

1

0

High-throughput

0.513

High

345102

APTX
Aprataxin

1

0

High-throughput

0.513

High

345103

PIWL4
Piwi-like protein 4

1

0

High-throughput

0.513

High

345107

MTA70
N6-adenosine-methyltransferase catalytic subunit

1

0

High-throughput

0.513

High

345127

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

0

High-throughput

0.513

High

345131

EPAS1
Endothelial PAS domain-containing protein 1

1

0

High-throughput

0.513

High

345132

SENP7
Sentrin-specific protease 7

1

0

High-throughput

0.513

High

345140

MOB1A
MOB kinase activator 1A

1

0

High-throughput

0.513

High

345151

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

345113

ZDH17
Palmitoyltransferase ZDHHC17

1

1

High-throughput

0.494

High

345038

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

345057

GRN
Progranulin

1

0

High-throughput

0.493

High

345138

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

1

High-throughput

0.489

High

345036

K2C1
Keratin, type II cytoskeletal 1

1

0

Small-scale

0.480

High

345043

INVO
Involucrin

1

0

Small-scale

0.480

High

345053

ELAF
Elafin

1

0

Small-scale

0.480

High

345055

LORI
Loricrin

1

0

Small-scale

0.480

High

345158

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

Small-scale

0.480

High

224256

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

345034

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

345040

S10A8
Protein S100-A8

1

2

High-throughput

0.479

High

345041

S10A9
Protein S100-A9

1

2

High-throughput

0.479

High

345052

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

345058

PML
Protein PML

1

1

High-throughput

0.479

High

345061

VHL
von Hippel-Lindau disease tumor suppressor

1

1

High-throughput

0.479

High

345064

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

345078

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

345089

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

345099

UBN2
Ubinuclein-2

1

1

High-throughput

0.479

High

345105

FGD2
FYVE, RhoGEF and PH domain-containing protein 2

1

1

High-throughput

0.479

High

345108

TLK2
Serine/threonine-protein kinase tousled-like 2

1

2

High-throughput

0.479

High

345109

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

345110

MET23
Histone-arginine methyltransferase METTL23

1

1

High-throughput

0.479

High

345115

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

345119

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

345133

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

345141

UBN1
Ubinuclein-1

1

1

High-throughput

0.479

High

345148

RHG20
Rho GTPase-activating protein 20

1

4

High-throughput

0.479

High

345157

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.479

High

197168

SERA
D-3-phosphoglycerate dehydrogenase

1

0

Small-scale

0.458

High

282452

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

High-throughput

0.458

High

319683

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

345035

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

345037

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

345039

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

345042

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

345046

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.458

High

345049

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

345050

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

345056

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

345059

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

Small-scale

0.458

High

345066

HIRA
Protein HIRA

1

0

High-throughput

0.458

High

345069

TBA1B
Tubulin alpha-1B chain

1

0

High-throughput

0.458

High

345072

VIGLN
Vigilin

1

0

High-throughput

0.458

High

345073

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

345074

DSG1
Desmoglein-1

1

0

High-throughput

0.458

High

345076

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

345077

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.458

High

345081

DX39B
Spliceosome RNA helicase DDX39B

1

0

High-throughput

0.458

High

345083

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

345084

ELOC
Elongin-C

1

0

High-throughput

0.458

High

345085

ELOB
Elongin-B

1

0

High-throughput

0.458

High

345088

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

345091

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

345093

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

345098

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

345111

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.458

High

345114

CDAN1
Codanin-1

1

0

High-throughput

0.458

High

345122

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

345123

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

345126

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.458

High

345128

SPB12
Serpin B12

1

0

High-throughput

0.458

High

345134

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

345135

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

345142

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

345143

ANLN
Anillin

1

0

High-throughput

0.458

High

345146

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

345154

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

0

Small-scale

0.458

High

345155

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.458

High

345159

CABIN
Calcineurin-binding protein cabin-1

1

0

High-throughput

0.458

High

345068

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

4

High-throughput

0.445

High

345090

ODFP2
Outer dense fiber protein 2

1

1

High-throughput

0.445

High

345054

PTN
Pleiotrophin

1

0

High-throughput

0.438

High

345124

KISSR
KiSS-1 receptor

1

1

Small-scale

0.437

High

345092

RNLS
Renalase

1

0

Small-scale

0.426

High

345118

POC5
Centrosomal protein POC5

1

0

Small-scale

0.426

High

345120

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

345095

Z518A
Zinc finger protein 518A

1

0

High-throughput

0.279

Low

345116

PARP8
Protein mono-ADP-ribosyltransferase PARP8

1

0

High-throughput

0.279

Low

345125

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.279

Low

345144

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

345152

SCML2
Sex comb on midleg-like protein 2

1

0

High-throughput

0.279

Low

345100

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

0

High-throughput

0.269

Low

103690

G5E9A7
DM1 locus, WD repeat containing

1

0

High-throughput

0.268

Low

281496

WFS1
Wolframin

1

0

High-throughput

0.268

Low

345156

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

100361

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

345070

DCD
Dermcidin

1

0

High-throughput

0.249

Low

345096

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

345106

CLC14
C-type lectin domain family 14 member A

1

0

Small-scale

0.249

Low

345137

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.249

Low

345147

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.249

Low

345067

CD81
CD81 antigen

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024