Protein: RIN1
Ras and Rab interactor 1 (Ras inhibitor JC99) (Ras interaction/interference protein 1)

Gene: RIN1
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q13671

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

349304

RASH
GTPase HRas

11

15

Small-scale

0.982

High

905422

RRAS2
Ras-related protein R-Ras2

5

15

Small-scale

0.931

High

348653

RASN
GTPase NRas

5

15

High-throughput

0.924

High

350154

RASK
GTPase KRas

2

16

High-throughput

0.811

High

488071

RRAS
Ras-related protein R-Ras

2

16

High-throughput

0.811

High

592240

RAB5A
Ras-related protein Rab-5A

2

20

Small-scale

0.783

High

337469

ABL1
Tyrosine-protein kinase ABL1

5

20

Small-scale

0.717

High

909542

1433E
14-3-3 protein epsilon

5

6

Small-scale

0.711

High

1044803

LZTS2
Leucine zipper putative tumor suppressor 2

4

7

High-throughput

0.705

High

789065

ABL2
Tyrosine-protein kinase ABL2

4

20

Small-scale

0.704

High

897983

RAP2B
Ras-related protein Rap-2b

1

6

High-throughput

0.691

High

904541

1433G
14-3-3 protein gamma

4

20

High-throughput

0.691

High

981994

1433F
14-3-3 protein eta

4

20

High-throughput

0.691

High

1044783

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

4

7

High-throughput

0.683

High

1044796

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

3

5

High-throughput

0.669

High

601918

ERBB3
Receptor tyrosine-protein kinase erbB-3

3

20

High-throughput

0.641

High

1025372

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

4

High-throughput

0.640

High

1044804

CCM2
Cerebral cavernous malformations 2 protein

3

0

High-throughput

0.636

High

338400

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.634

High

927023

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.628

High

876379

AFAD
Afadin

1

4

Small-scale

0.621

High

895350

RAB5B
Ras-related protein Rab-5B

1

20

Small-scale

0.621

High

1044764

RIN1
Ras and Rab interactor 1

1

12

High-throughput

0.618

High

1044765

GRB7
Growth factor receptor-bound protein 7

1

20

Small-scale

0.618

High

277058

STAM2
Signal transducing adapter molecule 2

2

8

Small-scale

0.612

High

235502

VINEX
Vinexin

2

17

High-throughput

0.606

High

253007

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.606

High

280577

KRT34
Keratin, type I cuticular Ha4

2

5

High-throughput

0.606

High

536820

TRI27
Zinc finger protein RFP

2

9

High-throughput

0.606

High

734622

TRI23
E3 ubiquitin-protein ligase TRIM23

2

4

High-throughput

0.606

High

1020650

TRAF2
TNF receptor-associated factor 2

2

10

High-throughput

0.606

High

1044766

SNX17
Sorting nexin-17

2

1

High-throughput

0.606

High

1044768

CIP4
Cdc42-interacting protein 4

2

4

High-throughput

0.606

High

1044772

KR151
Keratin-associated protein 15-1

2

3

High-throughput

0.606

High

1044775

KLH12
Kelch-like protein 12

2

1

High-throughput

0.606

High

1044776

PKHG4
Puratrophin-1

2

4

High-throughput

0.606

High

1044782

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

2

3

High-throughput

0.606

High

1044785

TBCD1
TBC1 domain family member 1

2

1

High-throughput

0.606

High

1044799

CPNS2
Calpain small subunit 2

2

2

High-throughput

0.606

High

1044807

CAR10
Caspase recruitment domain-containing protein 10

2

2

High-throughput

0.606

High

1044809

TRIM7
E3 ubiquitin-protein ligase TRIM7

2

9

High-throughput

0.606

High

1044813

TFP11
Tuftelin-interacting protein 11

2

1

High-throughput

0.606

High

1044806

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

2

0

High-throughput

0.602

High

1021721

GNDS
Ral guanine nucleotide dissociation stimulator

1

0

Small-scale

0.589

High

1044818

NS1BP
Influenza virus NS1A-binding protein

2

4

High-throughput

0.584

High

124856

EIF3F
Eukaryotic translation initiation factor 3 subunit F

2

0

High-throughput

0.580

High

1044767

SC23B
Protein transport protein Sec23B

2

0

High-throughput

0.580

High

1044802

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

1044812

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

966537

OTUD4
OTU domain-containing protein 4

2

1

High-throughput

0.571

High

1044790

SH2D3
SH2 domain-containing protein 3C

2

20

High-throughput

0.571

High

62299

GG6L9
Golgin subfamily A member 6-like protein 9

2

7

High-throughput

0.553

High

330562

ZBED1
E3 SUMO-protein ligase ZBED1

2

2

High-throughput

0.553

High

994856

GOGA2
Golgin subfamily A member 2

2

4

High-throughput

0.553

High

1044789

EFC4A
EF-hand calcium-binding domain-containing protein 4A

2

8

High-throughput

0.553

High

1044811

HM20A
High mobility group protein 20A

2

4

High-throughput

0.553

High

1044800

MYCBP
c-Myc-binding protein

2

0

High-throughput

0.547

High

1044817

SPIN1
Spindlin-1

2

0

High-throughput

0.547

High

149857

RFXK
DNA-binding protein RFXANK

1

2

High-throughput

0.536

High

230502

TRAK2
Trafficking kinesin-binding protein 2

1

6

High-throughput

0.536

High

1044791

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

4

High-throughput

0.536

High

1044793

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

1

High-throughput

0.536

High

1044797

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

1044808

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1044815

HSPB8
Heat shock protein beta-8

1

2

High-throughput

0.536

High

489033

H14
Histone H1.4

2

1

High-throughput

0.521

High

958022

RBM10
RNA-binding protein 10

2

6

High-throughput

0.521

High

1044769

SMAD2
Mothers against decapentaplegic homolog 2

1

1

Small-scale

0.515

High

1044774

Q49AR9
ANKS1A protein

1

10

High-throughput

0.515

High

278610

DCTN3
Dynactin subunit 3

1

0

High-throughput

0.513

High

307972

ZWINT
ZW10 interactor

1

0

High-throughput

0.513

High

597504

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.513

High

602523

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.513

High

1044771

INF2
Inverted formin-2

1

0

High-throughput

0.513

High

1044777

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1044779

DPP8
Dipeptidyl peptidase 8

1

0

High-throughput

0.513

High

1044794

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.513

High

1044816

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

0

High-throughput

0.513

High

683332

1433B
14-3-3 protein beta/alpha

1

20

Small-scale

0.506

High

383793

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.501

High

645967

CRBB3
Beta-crystallin B3

1

1

High-throughput

0.489

High

975427

PPARD
Peroxisome proliferator-activated receptor delta

1

1

High-throughput

0.489

High

1044788

KLH34
Kelch-like protein 34

1

6

High-throughput

0.489

High

1044798

KLH29
Kelch-like protein 29

1

1

High-throughput

0.489

High

1044801

NPAS1
Neuronal PAS domain-containing protein 1

1

5

High-throughput

0.489

High

1044810

DNAI2
Dynein axonemal intermediate chain 2

1

2

High-throughput

0.489

High

1044784

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

High-throughput

0.481

High

1044787

KR131
Keratin-associated protein 13-1

1

3

High-throughput

0.481

High

1044795

TSC1
Hamartin

1

6

High-throughput

0.481

High

346731

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

411382

INSR
Insulin receptor

1

20

Small-scale

0.479

High

452419

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.479

High

507988

FGFR1
Fibroblast growth factor receptor 1

1

19

Small-scale

0.479

High

921557

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.479

High

980684

TLE2
Transducin-like enhancer protein 2

1

4

High-throughput

0.479

High

1044781

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.479

High

1044814

TES
Testin

1

8

High-throughput

0.479

High

1044786

Q86WV8
TSC complex subunit 1

1

3

High-throughput

0.470

High

1044778

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

1044792

FLCN
Folliculin

1

0

Small-scale

0.458

High

1044780

PKHG7
Pleckstrin homology domain-containing family G member 7

1

8

High-throughput

0.445

High

1044770

ITSN1
Intersectin-1

1

13

High-throughput

0.408

High

1044805

SPNDC
Spindlin interactor and repressor of chromatin-binding protein

2

0

High-throughput

0.298

High

224936

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.279

Low

245689

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

898010

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.279

Low

1044773

AMZ1
Archaemetzincin-1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024