Protein: PDCD4
Programmed cell death protein 4 (Neoplastic transformation inhibitor protein) (Nuclear antigen H731-like) (Protein 197/15a)

Gene: PDCD4
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q53EL6

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892823

IF4A1
Eukaryotic initiation factor 4A-I

9

15

Small-scale

0.976

High

1051874

IF4A2
Eukaryotic initiation factor 4A-II

5

15

High-throughput

0.930

High

757641

IF4A3
Eukaryotic initiation factor 4A-III

4

17

High-throughput

0.903

High

979920

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

2

3

Small-scale

0.776

High

1120036

FBW1A
F-box/WD repeat-containing protein 1A

9

5

Small-scale

0.754

High

1120031

FBW1B
F-box/WD repeat-containing protein 11

7

5

Small-scale

0.742

High

1120002

DDX60
Probable ATP-dependent RNA helicase DDX60

1

2

High-throughput

0.691

High

806038

RL5
Large ribosomal subunit protein uL18

2

1

Small-scale

0.636

High

1120019

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

5

High-throughput

0.618

High

1120000

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

1

High-throughput

0.609

High

1105458

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

4

High-throughput

0.602

High

1120001

TF2LY
Homeobox protein TGIF2LY

2

0

High-throughput

0.602

High

1120006

H2B1H
Histone H2B type 1-H

2

8

High-throughput

0.601

High

834982

PSN2
Presenilin-2

1

2

High-throughput

0.590

High

125504

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

2

Small-scale

0.584

High

552874

RFA2
Replication protein A 32 kDa subunit

2

2

High-throughput

0.584

High

918409

H2B1C
Histone H2B type 1-C/E/F/G/I

2

8

High-throughput

0.584

High

998796

EP300
Histone acetyltransferase p300

2

2

High-throughput

0.584

High

1119998

SLN11
Schlafen family member 11

2

1

Small-scale

0.584

High

398890

HMGN2
Non-histone chromosomal protein HMG-17

2

0

High-throughput

0.576

High

805434

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

1

High-throughput

0.571

High

616712

KS6B1
Ribosomal protein S6 kinase beta-1

1

3

Small-scale

0.569

High

934214

CSK21
Casein kinase II subunit alpha

1

6

High-throughput

0.569

High

361492

APOE
Apolipoprotein E

1

0

High-throughput

0.565

High

1031211

SKP2
S-phase kinase-associated protein 2

1

1

Small-scale

0.561

High

1120015

MEP50
Methylosome protein WDR77

1

2

Small-scale

0.561

High

1120024

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

Small-scale

0.561

High

1120010

EP400
E1A-binding protein p400

1

1

High-throughput

0.553

High

911154

RS13
Small ribosomal subunit protein uS15

1

1

Small-scale

0.552

High

1120003

ABI1
Abl interactor 1

2

0

High-throughput

0.547

High

271335

NPM3
Nucleoplasmin-3

1

3

High-throughput

0.536

High

275889

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

6

High-throughput

0.536

High

283537

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.536

High

380302

HG2A
HLA class II histocompatibility antigen gamma chain

1

2

High-throughput

0.536

High

403249

LA
Lupus La protein

1

4

High-throughput

0.536

High

418336

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

447952

SRP19
Signal recognition particle 19 kDa protein

1

1

High-throughput

0.536

High

828780

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

907948

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

911406

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.536

High

923045

RL11
Large ribosomal subunit protein uL5

1

2

High-throughput

0.536

High

929491

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.536

High

1062353

CND2
Condensin complex subunit 2

1

1

High-throughput

0.536

High

1120004

PSPC1
Paraspeckle component 1

1

7

High-throughput

0.536

High

1120016

RBM42
RNA-binding protein 42

1

4

High-throughput

0.536

High

1120025

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

2

High-throughput

0.536

High

1120030

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

1120033

G3BP2
Ras GTPase-activating protein-binding protein 2

1

4

High-throughput

0.536

High

1120035

DRG1
Developmentally-regulated GTP-binding protein 1

1

1

High-throughput

0.536

High

1120037

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.536

High

883024

H2BFS
Histone H2B type F-S

1

8

High-throughput

0.515

High

886122

H2B1D
Histone H2B type 1-D

1

8

High-throughput

0.515

High

1087161

H2B2E
Histone H2B type 2-E

1

8

High-throughput

0.515

High

1120014

H2B1M
Histone H2B type 1-M

1

8

High-throughput

0.515

High

978779

TF65
Transcription factor p65

1

0

Small-scale

0.513

High

153690

ANM5
Protein arginine N-methyltransferase 5

1

2

Small-scale

0.501

High

174942

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

681882

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.501

High

902615

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

1073430

KS6A1
Ribosomal protein S6 kinase alpha-1

1

3

Small-scale

0.501

High

1119994

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.501

High

360004

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.493

High

1120032

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

High-throughput

0.489

High

834297

PSN1
Presenilin-1

1

2

High-throughput

0.481

High

123961

SPT5H
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

162815

XPO1
Exportin-1

1

6

High-throughput

0.479

High

227645

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

230761

AQR
RNA helicase aquarius

1

1

High-throughput

0.479

High

241547

H2B1K
Histone H2B type 1-K

1

8

High-throughput

0.479

High

384949

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

420840

H2B1J
Histone H2B type 1-J

1

8

High-throughput

0.479

High

453397

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

3

High-throughput

0.479

High

651368

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

779527

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

809323

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

1

High-throughput

0.479

High

813517

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

874999

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

917379

H4
Histone H4

1

1

High-throughput

0.479

High

924021

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

3

High-throughput

0.479

High

924317

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

High-throughput

0.479

High

925052

TRA2B
Transformer-2 protein homolog beta

1

5

High-throughput

0.479

High

934832

H31
Histone H3.1

1

1

High-throughput

0.479

High

973346

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.479

High

1036630

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

1043030

CUL4A
Cullin-4A

1

2

Small-scale

0.479

High

1063841

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

1064374

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1119996

ATAD2
ATPase family AAA domain-containing protein 2

1

4

High-throughput

0.479

High

1119997

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1119999

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1120008

H2B1A
Histone H2B type 1-A

1

8

High-throughput

0.479

High

1120012

RSF1
Remodeling and spacing factor 1

1

4

High-throughput

0.479

High

1120013

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

1120017

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

1

Small-scale

0.479

High

1120020

ANLN
Anillin

1

1

High-throughput

0.479

High

1120023

DTL
Denticleless protein homolog

1

2

Small-scale

0.479

High

1120026

KS6B2
Ribosomal protein S6 kinase beta-2

1

3

High-throughput

0.479

High

1120028

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1120038

RBM8A
RNA-binding protein 8A

1

5

High-throughput

0.479

High

838873

EMD
Emerin

1

0

Small-scale

0.458

High

1062155

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1120005

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1120009

INT12
Integrator complex subunit 12

1

0

High-throughput

0.458

High

1120011

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1120018

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.458

High

1120022

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1120027

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

1120029

TCF20
Transcription factor 20

1

0

High-throughput

0.458

High

1120034

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.458

High

988921

FMR1
Fragile X messenger ribonucleoprotein 1

1

5

High-throughput

0.445

High

400324

RLA1
Large ribosomal subunit protein P1

1

0

Small-scale

0.438

High

720619

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

824079

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.437

High

484134

CALM3
Calmodulin-3

1

0

High-throughput

0.426

High

1120021

TMM51
Transmembrane protein 51

3

0

High-throughput

0.347

High

62943

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.249

Low

887871

CD81
CD81 antigen

1

0

High-throughput

0.249

Low

1119995

ARID2
AT-rich interactive domain-containing protein 2

1

0

High-throughput

0.249

Low

1120007

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024