Protein: FREM2
FRAS1-related extracellular matrix protein 2 (ECM3 homolog)

Gene: FREM2
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q5SZK8

Gene Ontology (top 5):
GO:0001654 - eye development
GO:0001822 - kidney development
GO:0002009 - morphogenesis of an epithelium
GO:0005604 - basement membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350975

PDGFB
Platelet-derived growth factor subunit B

2

6

High-throughput

0.628

High

519338

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

4

High-throughput

0.628

High

1132303

DKKL1
Dickkopf-like protein 1

2

9

High-throughput

0.628

High

1132304

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

17

High-throughput

0.628

High

1132309

PCDGD
Protocadherin gamma-B1

2

19

High-throughput

0.628

High

1125873

FREM1
FRAS1-related extracellular matrix protein 1

1

12

Small-scale

0.618

High

439338

CATG
Cathepsin G

2

17

High-throughput

0.611

High

713820

RYK
Tyrosine-protein kinase RYK

2

14

Small-scale

0.611

High

305219

NXPH2
Neurexophilin-2

3

11

High-throughput

0.609

High

67759

ZBBX
Zinc finger B-box domain-containing protein 1

2

4

High-throughput

0.574

High

328134

SG1D1
Secretoglobin family 1D member 1

2

3

High-throughput

0.574

High

965238

DEF5
Defensin alpha 5

2

2

High-throughput

0.574

High

1132295

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

4

High-throughput

0.574

High

1132298

TAFA4
Chemokine-like protein TAFA-4

2

4

High-throughput

0.574

High

1132302

XAGE1
X antigen family member 1

2

9

High-throughput

0.549

High

159759

LECT2
Leukocyte cell-derived chemotaxin-2

1

1

High-throughput

0.536

High

449285

LEG1
Galectin-1

1

11

High-throughput

0.536

High

578226

LAG3
Lymphocyte activation gene 3 protein

1

4

High-throughput

0.536

High

621371

CMA1
Chymase

1

18

High-throughput

0.536

High

685251

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

17

High-throughput

0.536

High

726521

TIMP3
Metalloproteinase inhibitor 3

1

2

High-throughput

0.536

High

806553

RL28
Large ribosomal subunit protein eL28

1

4

High-throughput

0.536

High

1132290

ATS17
A disintegrin and metalloproteinase with thrombospondin motifs 17

1

12

High-throughput

0.536

High

1132291

DCNP1
Dendritic cell nuclear protein 1

1

7

High-throughput

0.536

High

1132307

HYOU1
Hypoxia up-regulated protein 1

1

4

High-throughput

0.536

High

453404

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.515

High

1132299

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.513

High

63925

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

9

High-throughput

0.489

High

1020714

TRAF2
TNF receptor-associated factor 2

1

3

High-throughput

0.489

High

1132286

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

14

High-throughput

0.489

High

1132287

TAFA5
Chemokine-like protein TAFA-5

1

4

High-throughput

0.489

High

1132288

TAFA2
Chemokine-like protein TAFA-2

1

4

High-throughput

0.489

High

1132293

BMAL2
Basic helix-loop-helix ARNT-like protein 2

1

1

High-throughput

0.489

High

1132296

UCN3
Urocortin-3

1

4

High-throughput

0.489

High

352637

TNFA
Tumor necrosis factor

1

2

High-throughput

0.479

High

903976

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

High-throughput

0.479

High

1084710

TAZ
Tafazzin

1

4

High-throughput

0.479

High

1132283

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.479

High

1132292

LIPH
Lipase member H

1

3

High-throughput

0.479

High

1132297

CALR3
Calreticulin-3

1

2

High-throughput

0.479

High

117157

DX39A
ATP-dependent RNA helicase DDX39A

1

4

High-throughput

0.437

High

890197

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.437

High

1132285

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1132289

DTWD2
tRNA-uridine aminocarboxypropyltransferase 2

1

2

High-throughput

0.437

High

1132294

DNS2B
Deoxyribonuclease-2-beta

1

2

High-throughput

0.437

High

1132300

CHST8
Carbohydrate sulfotransferase 8

1

1

High-throughput

0.437

High

1132301

WDR76
WD repeat-containing protein 76

1

1

High-throughput

0.437

High

1132306

KLK5
Kallikrein-5

1

9

High-throughput

0.437

High

624922

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.279

Low

1132284

TRI68
E3 ubiquitin-protein ligase TRIM68

1

0

High-throughput

0.279

Low

1132305

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

1132308

INSL6
Insulin-like peptide INSL6

1

0

High-throughput

0.279

Low

71147

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024