Protein: MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)

Gene: MACF1
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q9UPN3

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1077170

MARE1
Microtubule-associated protein RP/EB family member 1

6

13

Small-scale

0.948

High

282289

CDKL5
Cyclin-dependent kinase-like 5

2

14

High-throughput

0.789

High

836093

GSK3B
Glycogen synthase kinase-3 beta

2

18

High-throughput

0.754

High

1356411

TNIK
TRAF2 and NCK-interacting protein kinase

2

20

High-throughput

0.743

High

234595

DSCAM
Cell adhesion molecule DSCAM

1

10

High-throughput

0.698

High

800961

MK09
Mitogen-activated protein kinase 9

1

11

High-throughput

0.698

High

363350

FINC
Fibronectin

1

13

High-throughput

0.691

High

1296190

SCYL1
N-terminal kinase-like protein

1

13

High-throughput

0.691

High

1357666

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

5

High-throughput

0.691

High

1271386

NRCAM
Neuronal cell adhesion molecule

1

9

Small-scale

0.656

High

370715

ESR1
Estrogen receptor

3

20

High-throughput

0.650

High

943023

SRPK2
SRSF protein kinase 2

1

12

High-throughput

0.647

High

984550

KPCD
Protein kinase C delta type

1

4

Small-scale

0.647

High

1330882

Q9H4D1
Protein kinase

1

20

High-throughput

0.621

High

1292298

AURKB
Aurora kinase B

1

6

High-throughput

0.618

High

149428

CTRO
Citron Rho-interacting kinase

1

15

High-throughput

0.618

High

411889

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.618

High

434078

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.618

High

647985

MARK3
MAP/microtubule affinity-regulating kinase 3

1

6

Small-scale

0.618

High

725073

MYH9
Myosin-9

1

10

High-throughput

0.618

High

742612

SYUA
Alpha-synuclein

1

3

High-throughput

0.618

High

835567

GSK3A
Glycogen synthase kinase-3 alpha

1

17

High-throughput

0.618

High

892113

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.618

High

934560

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.618

High

1068700

PLEC
Plectin

1

16

High-throughput

0.618

High

1071717

KS6A2
Ribosomal protein S6 kinase alpha-2

1

3

High-throughput

0.618

High

1168748

SYNE3
Nesprin-3

1

20

High-throughput

0.618

High

1172280

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

1357665

MARE3
Microtubule-associated protein RP/EB family member 3

1

13

High-throughput

0.618

High

1303862

CDC5L
Cell division cycle 5-like protein

2

10

High-throughput

0.614

High

320446

SNP29
Synaptosomal-associated protein 29

2

1

High-throughput

0.611

High

719790

RADI
Radixin

2

17

High-throughput

0.611

High

1042847

CUL3
Cullin-3

2

12

High-throughput

0.611

High

581890

VCAM1
Vascular cell adhesion protein 1

2

14

High-throughput

0.601

High

883671

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

20

High-throughput

0.590

High

1285924

CHP3
Calcineurin B homologous protein 3

1

3

High-throughput

0.590

High

1344836

DISC1
Disrupted in schizophrenia 1 protein

2

10

High-throughput

0.590

High

1346356

EXOC1
Exocyst complex component 1

2

3

High-throughput

0.590

High

256153

OBSL1
Obscurin-like protein 1

2

20

High-throughput

0.584

High

348245

MYC
Myc proto-oncogene protein

2

14

High-throughput

0.584

High

683813

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.584

High

910159

1433E
14-3-3 protein epsilon

2

4

High-throughput

0.584

High

927659

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.584

High

1298096

CEP63
Centrosomal protein of 63 kDa

3

20

High-throughput

0.576

High

965174

ANK2
Ankyrin-2

1

20

High-throughput

0.575

High

870933

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

10

Small-scale

0.561

High

1356997

HECD1
E3 ubiquitin-protein ligase HECTD1

1

17

High-throughput

0.553

High

1273964

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

11

Small-scale

0.543

High

317377

PCNT
Pericentrin

1

20

High-throughput

0.541

High

402627

JUN
Transcription factor Jun

1

6

High-throughput

0.541

High

626291

APC
Adenomatous polyposis coli protein

1

19

High-throughput

0.541

High

878153

PKNX1
Homeobox protein PKNOX1

1

1

High-throughput

0.541

High

1044584

FHL1
Four and a half LIM domains protein 1

1

8

High-throughput

0.541

High

529917

CFTR
Cystic fibrosis transmembrane conductance regulator

1

9

High-throughput

0.536

High

565990

AATC
Aspartate aminotransferase, cytoplasmic

1

4

High-throughput

0.536

High

818611

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.536

High

970613

ID2
DNA-binding protein inhibitor ID-2

1

1

High-throughput

0.536

High

1127209

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

20

High-throughput

0.536

High

1255339

MIPT3
TRAF3-interacting protein 1

2

6

High-throughput

0.526

High

415541

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.515

High

973289

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.515

High

1061289

NUMA1
Nuclear mitotic apparatus protein 1

1

20

High-throughput

0.515

High

1312791

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

521407

SKIL
Ski-like protein

1

3

High-throughput

0.508

High

825763

MTR1B
Melatonin receptor type 1B

1

9

High-throughput

0.508

High

1290416

DTBP1
Dysbindin

1

4

High-throughput

0.508

High

1355322

CNTP2
Contactin-associated protein-like 2

1

10

Small-scale

0.508

High

1357667

PLXD1
Plexin-D1

1

5

Small-scale

0.508

High

476576

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

13

High-throughput

0.501

High

311021

SNAPN
SNARE-associated protein Snapin

1

4

High-throughput

0.494

High

819684

NRIP1
Nuclear receptor-interacting protein 1

1

3

High-throughput

0.494

High

63951

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

1

High-throughput

0.489

High

304502

ALX3
Homeobox protein aristaless-like 3

1

3

High-throughput

0.489

High

1357669

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.489

High

1318933

TNG6
Transport and Golgi organization protein 6 homolog

1

0

Small-scale

0.486

High

510045

ERR1
Steroid hormone receptor ERR1

1

20

High-throughput

0.481

High

885673

NRX1B
Neurexin-1-beta

1

3

Small-scale

0.481

High

885678

NRX2B
Neurexin-2-beta

1

3

Small-scale

0.481

High

1356681

TEN1
Teneurin-1

1

5

Small-scale

0.481

High

151258

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

14

High-throughput

0.479

High

213064

STX6
Syntaxin-6

1

7

High-throughput

0.479

High

233687

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

236136

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

High-throughput

0.479

High

279760

FLOT1
Flotillin-1

1

7

High-throughput

0.479

High

303536

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

309164

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

323313

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

430383

PROF1
Profilin-1

1

4

High-throughput

0.479

High

448857

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.479

High

489344

H14
Histone H1.4

1

4

High-throughput

0.479

High

507315

LAMP1
Lysosome-associated membrane glycoprotein 1

1

13

High-throughput

0.479

High

522274

CADH1
Cadherin-1

1

13

High-throughput

0.479

High

531305

EF2
Elongation factor 2

1

8

High-throughput

0.479

High

539189

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

1

High-throughput

0.479

High

547281

EZRI
Ezrin

1

20

High-throughput

0.479

High

567331

CXA1
Gap junction alpha-1 protein

1

14

High-throughput

0.479

High

575872

VINC
Vinculin

1

13

High-throughput

0.479

High

592583

RAB5A
Ras-related protein Rab-5A

1

13

High-throughput

0.479

High

610110

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.479

High

647380

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

657563

TMOD1
Tropomodulin-1

1

3

High-throughput

0.479

High

684396

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

716807

CTNA1
Catenin alpha-1

1

11

High-throughput

0.479

High

803811

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.479

High

813212

CAZA2
F-actin-capping protein subunit alpha-2

1

7

High-throughput

0.479

High

823516

PAXI
Paxillin

1

11

High-throughput

0.479

High

825884

NASP
Nuclear autoantigenic sperm protein

1

4

High-throughput

0.479

High

832781

MCM2
DNA replication licensing factor MCM2

1

11

High-throughput

0.479

High

843098

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.479

High

897860

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.479

High

905261

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

970070

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

975113

CAV1
Caveolin-1

1

15

High-throughput

0.479

High

982620

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

997237

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

8

High-throughput

0.479

High

1029357

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.479

High

1030557

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1051517

DCTN1
Dynactin subunit 1

1

16

High-throughput

0.479

High

1056166

NBR1
Next to BRCA1 gene 1 protein

1

4

High-throughput

0.479

High

1061690

CUL7
Cullin-7

1

9

High-throughput

0.479

High

1064839

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.479

High

1066880

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

1080815

ZYX
Zyxin

1

11

High-throughput

0.479

High

1084242

OCLN
Occludin

1

7

High-throughput

0.479

High

1148273

RNF43
E3 ubiquitin-protein ligase RNF43

1

6

High-throughput

0.479

High

1169511

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

20

High-throughput

0.479

High

1190204

CLAP1
CLIP-associating protein 1

1

3

High-throughput

0.479

High

1267260

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

11

High-throughput

0.479

High

1271274

GOGA1
Golgin subfamily A member 1

1

14

High-throughput

0.479

High

1281478

FBXW7
F-box/WD repeat-containing protein 7

1

13

High-throughput

0.479

High

1286754

CHM4C
Charged multivesicular body protein 4c

1

19

High-throughput

0.479

High

1287432

OPTN
Optineurin

1

20

High-throughput

0.479

High

1299417

RBM14
RNA-binding protein 14

1

1

High-throughput

0.479

High

1304437

DNJC2
DnaJ homolog subfamily C member 2

1

1

High-throughput

0.479

High

1319134

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

4

High-throughput

0.479

High

1328305

CCDC8
Coiled-coil domain-containing protein 8

1

8

High-throughput

0.479

High

1331636

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1333811

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

1343798

ANLN
Anillin

1

14

High-throughput

0.479

High

1344536

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

13

High-throughput

0.479

High

1350503

HECW2
E3 ubiquitin-protein ligase HECW2

1

6

High-throughput

0.479

High

1354871

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1355078

TES
Testin

1

19

High-throughput

0.479

High

1357668

LOXL2
Lysyl oxidase homolog 2

1

2

High-throughput

0.479

High

1318793

CNTP4
Contactin-associated protein-like 4

1

10

Small-scale

0.464

High

1356730

RAB21
Ras-related protein Rab-21

1

14

Small-scale

0.462

High

127895

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

922469

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

1184386

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1231079

S39AB
Zinc transporter ZIP11

1

0

High-throughput

0.458

High

1238853

TTC29
Tetratricopeptide repeat protein 29

1

0

High-throughput

0.458

High

989194

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.457

High

1350554

NRX2A
Neurexin-2

1

13

Small-scale

0.457

High

1356807

NRX1A
Neurexin-1

1

13

Small-scale

0.457

High

1357670

CD2AP
CD2-associated protein

1

16

High-throughput

0.457

High

378217

PRIO
Major prion protein

1

1

High-throughput

0.445

High

882642

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

10

High-throughput

0.445

High

1245642

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

4

High-throughput

0.445

High

1313659

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

1

14

High-throughput

0.445

High

1318902

ZDHC5
Palmitoyltransferase ZDHHC5

1

3

High-throughput

0.445

High

1131039

SNP47
Synaptosomal-associated protein 47

1

0

Small-scale

0.438

High

101291

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

330019

AGR2
Anterior gradient protein 2 homolog

1

9

High-throughput

0.437

High

554062

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.437

High

652612

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.437

High

721787

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.437

High

831805

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

Small-scale

0.437

High

903607

WDR5
WD repeat-containing protein 5

1

14

High-throughput

0.437

High

909332

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

8

High-throughput

0.437

High

1075030

TERF2
Telomeric repeat-binding factor 2

1

10

High-throughput

0.437

High

1159471

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

1200759

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.437

High

1239770

NHLC2
NHL repeat-containing protein 2

1

2

High-throughput

0.437

High

1256080

RHBL4
Rhomboid-related protein 4

1

3

Small-scale

0.437

High

1269937

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1271857

ATOH1
Transcription factor ATOH1

1

6

Small-scale

0.437

High

1354573

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.437

High

886365

DSCR9
Down syndrome critical region protein 9

1

3

High-throughput

0.417

High

1167137

MCAF1
Activating transcription factor 7-interacting protein 1

1

10

High-throughput

0.417

High

718318

BMI1
Polycomb complex protein BMI-1

1

19

High-throughput

0.407

High

1150095

AMERL
AMMECR1-like protein

3

0

High-throughput

0.347

High

1295505

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

666433

3MG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024