Protein: UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin-specific peptidase 53)

Gene: UBP53, USP53
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q70EK8

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0005911 - cell-cell junction
GO:0005923 - bicellular tight junction
GO:0007605 - sensory perception of sound
GO:0010996 - response to auditory stimulus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

802636

CRK
Adapter molecule crk

4

9

High-throughput

0.642

High

1173990

DDB2
DNA damage-binding protein 2

1

11

Small-scale

0.637

High

475955

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.579

High

802864

CRKL
Crk-like protein

2

10

High-throughput

0.553

High

1173983

RPTOR
Regulatory-associated protein of mTOR

1

8

Small-scale

0.553

High

1173986

COP1
E3 ubiquitin-protein ligase COP1

1

16

High-throughput

0.553

High

924661

GRB2
Growth factor receptor-bound protein 2

1

8

High-throughput

0.541

High

1173991

NECT2
Nectin-2

1

1

High-throughput

0.541

High

958469

CYC
Cytochrome c

1

1

Small-scale

0.512

High

1020757

TRAF2
TNF receptor-associated factor 2

1

20

High-throughput

0.494

High

519022

PIP
Prolactin-inducible protein

1

1

High-throughput

0.489

High

409130

K2C8
Keratin, type II cytoskeletal 8

1

2

Small-scale

0.479

High

717176

CTNB1
Catenin beta-1

1

10

Small-scale

0.479

High

885263

EPIPL
Epiplakin

1

13

Small-scale

0.479

High

1173988

PDC6I
Programmed cell death 6-interacting protein

1

9

Small-scale

0.479

High

1174012

ZO2
Tight junction protein ZO-2

1

1

High-throughput

0.479

High

1174019

PKP3
Plakophilin-3

1

12

Small-scale

0.479

High

672440

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

4

High-throughput

0.470

High

683103

CASPE
Caspase-14

1

2

High-throughput

0.470

High

848240

HCFC1
Host cell factor 1

1

5

High-throughput

0.470

High

893697

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.470

High

898659

RL26
Large ribosomal subunit protein uL24

1

2

High-throughput

0.470

High

1046232

BLMH
Bleomycin hydrolase

1

1

High-throughput

0.470

High

1052894

FLNC
Filamin-C

1

6

High-throughput

0.470

High

1173993

RAD50
DNA repair protein RAD50

1

9

High-throughput

0.470

High

1174011

CPNE7
Copine-7

1

1

High-throughput

0.470

High

269160

DAB1
Disabled homolog 1

1

6

High-throughput

0.439

High

64118

AXA2L
Putative annexin A2-like protein

1

3

High-throughput

0.437

High

92250

E9PAV9
G patch domain-containing protein 4

1

1

Small-scale

0.437

High

133542

NOP56
Nucleolar protein 56

1

4

Small-scale

0.437

High

136034

ACACB
Acetyl-CoA carboxylase 2

1

8

Small-scale

0.437

High

150228

AP3D1
AP-3 complex subunit delta-1

1

2

Small-scale

0.437

High

164631

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

6

Small-scale

0.437

High

165511

SR140
U2 snRNP-associated SURP motif-containing protein

1

3

Small-scale

0.437

High

181710

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

8

Small-scale

0.437

High

257637

ANR17
Ankyrin repeat domain-containing protein 17

1

3

Small-scale

0.437

High

320131

RAB3D
Ras-related protein Rab-3D

1

2

Small-scale

0.437

High

349423

RASH
GTPase HRas

1

3

High-throughput

0.437

High

398265

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

8

Small-scale

0.437

High

408848

K1C18
Keratin, type I cytoskeletal 18

1

8

Small-scale

0.437

High

430989

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

1

Small-scale

0.437

High

453971

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

1

Small-scale

0.437

High

513592

PYC
Pyruvate carboxylase, mitochondrial

1

8

Small-scale

0.437

High

514027

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

Small-scale

0.437

High

524964

XRCC5
X-ray repair cross-complementing protein 5

1

3

Small-scale

0.437

High

561607

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

2

Small-scale

0.437

High

573331

TCPA
T-complex protein 1 subunit alpha

1

5

Small-scale

0.437

High

585494

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

4

Small-scale

0.437

High

603567

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

Small-scale

0.437

High

684151

1433S
14-3-3 protein sigma

1

20

High-throughput

0.437

High

708472

MCM4
DNA replication licensing factor MCM4

1

7

Small-scale

0.437

High

708955

MCM7
DNA replication licensing factor MCM7

1

7

Small-scale

0.437

High

722255

RFC1
Replication factor C subunit 1

1

3

Small-scale

0.437

High

727277

NU214
Nuclear pore complex protein Nup214

1

9

Small-scale

0.437

High

741061

ZEB1
Zinc finger E-box-binding homeobox 1

1

7

Small-scale

0.437

High

801215

KI67
Proliferation marker protein Ki-67

1

10

Small-scale

0.437

High

806056

RL5
Large ribosomal subunit protein uL18

1

1

Small-scale

0.437

High

858001

NUP98
Nuclear pore complex protein Nup98-Nup96

1

6

Small-scale

0.437

High

863254

COPB
Coatomer subunit beta

1

2

Small-scale

0.437

High

873442

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

1

Small-scale

0.437

High

904760

1433G
14-3-3 protein gamma

1

20

High-throughput

0.437

High

916662

RS6
Small ribosomal subunit protein eS6

1

2

Small-scale

0.437

High

919431

RL23
Large ribosomal subunit protein uL14

1

1

Small-scale

0.437

High

940708

NOP14
Nucleolar protein 14

1

1

Small-scale

0.437

High

966426

EXOSX
Exosome complex component 10

1

2

Small-scale

0.437

High

980420

NOTC2
Neurogenic locus notch homolog protein 2

1

5

Small-scale

0.437

High

982186

1433F
14-3-3 protein eta

1

20

High-throughput

0.437

High

983389

DYN1
Dynamin-1

1

1

Small-scale

0.437

High

1001519

Q0IIN1
Keratin 77

1

6

High-throughput

0.437

High

1024038

ACACA
Acetyl-CoA carboxylase 1

1

8

Small-scale

0.437

High

1034909

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

2

Small-scale

0.437

High

1045610

NOG2
Nucleolar GTP-binding protein 2

1

3

Small-scale

0.437

High

1051586

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

4

Small-scale

0.437

High

1051969

ELOA1
Elongin-A

1

6

Small-scale

0.437

High

1052691

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

17

Small-scale

0.437

High

1056583

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

11

Small-scale

0.437

High

1068581

PLEC
Plectin

1

11

Small-scale

0.437

High

1080058

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

Small-scale

0.437

High

1129759

TDIF2
Deoxynucleotidyltransferase terminal-interacting protein 2

1

1

Small-scale

0.437

High

1131340

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

Small-scale

0.437

High

1160343

ALKB5
RNA demethylase ALKBH5

1

1

Small-scale

0.437

High

1173976

DDX46
Probable ATP-dependent RNA helicase DDX46

1

9

Small-scale

0.437

High

1173977

K2C1B
Keratin, type II cytoskeletal 1b

1

5

High-throughput

0.437

High

1173978

DDX42
ATP-dependent RNA helicase DDX42

1

8

Small-scale

0.437

High

1173979

INLR1
Interferon lambda receptor 1

1

2

Small-scale

0.437

High

1173981

SUGP2
SURP and G-patch domain-containing protein 2

1

1

Small-scale

0.437

High

1173982

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

4

Small-scale

0.437

High

1173985

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

9

Small-scale

0.437

High

1173987

BICD2
Protein bicaudal D homolog 2

1

10

High-throughput

0.437

High

1173989

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

4

Small-scale

0.437

High

1173992

SYN2
Synapsin-2

1

2

Small-scale

0.437

High

1173994

BICD1
Protein bicaudal D homolog 1

1

12

High-throughput

0.437

High

1173995

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

12

Small-scale

0.437

High

1173996

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

1

Small-scale

0.437

High

1173997

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

8

Small-scale

0.437

High

1173998

TCHP
Trichoplein keratin filament-binding protein

1

5

Small-scale

0.437

High

1173999

PCGF6
Polycomb group RING finger protein 6

1

18

Small-scale

0.437

High

1174000

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.437

High

1174001

GTPB4
GTP-binding protein 4

1

2

Small-scale

0.437

High

1174002

DDX24
ATP-dependent RNA helicase DDX24

1

16

Small-scale

0.437

High

1174003

SYF1
Pre-mRNA-splicing factor SYF1

1

4

Small-scale

0.437

High

1174005

HELLS
Lymphoid-specific helicase

1

11

Small-scale

0.437

High

1174006

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

2

Small-scale

0.437

High

1174007

DDX18
ATP-dependent RNA helicase DDX18

1

14

Small-scale

0.437

High

1174008

RBM28
RNA-binding protein 28

1

5

Small-scale

0.437

High

1174009

SLTM
SAFB-like transcription modulator

1

11

Small-scale

0.437

High

1174010

TMOD2
Tropomodulin-2

1

1

Small-scale

0.437

High

1174013

BAZ1B
Tyrosine-protein kinase BAZ1B

1

18

Small-scale

0.437

High

1174014

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

10

Small-scale

0.437

High

1174015

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

1

Small-scale

0.437

High

1174016

NINL
Ninein-like protein

1

13

High-throughput

0.437

High

1174017

ZN281
Zinc finger protein 281

1

2

Small-scale

0.437

High

1174018

NOC2L
Nucleolar complex protein 2 homolog

1

1

Small-scale

0.437

High

1129561

SMAG2
Protein Smaug homolog 2

2

0

High-throughput

0.316

High

816818

IREB2
Iron-responsive element-binding protein 2

1

0

High-throughput

0.282

High

345100

CYTA
Cystatin-A

1

0

High-throughput

0.269

Low

373397

CATA
Catalase

1

0

High-throughput

0.269

Low

396255

ARGI1
Arginase-1

1

0

High-throughput

0.269

Low

629146

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.269

Low

970802

DSG1
Desmoglein-1

1

0

High-throughput

0.269

Low

993964

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.269

Low

1174004

YAE1
Protein YAE1 homolog

1

0

High-throughput

0.269

Low

314346

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

337246

AATM
Aspartate aminotransferase, mitochondrial

1

0

Small-scale

0.249

Low

453433

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

0

Small-scale

0.249

Low

506189

PYGB
Glycogen phosphorylase, brain form

1

0

Small-scale

0.249

Low

534119

T2FB
General transcription factor IIF subunit 2

1

0

Small-scale

0.249

Low

622683

ERD21
ER lumen protein-retaining receptor 1

1

0

Small-scale

0.249

Low

718947

PHB1
Prohibitin 1

1

0

Small-scale

0.249

Low

827449

EFTU
Elongation factor Tu, mitochondrial

1

0

Small-scale

0.249

Low

855499

MSH6
DNA mismatch repair protein Msh6

1

0

Small-scale

0.249

Low

907700

RS15A
Small ribosomal subunit protein uS8

1

0

Small-scale

0.249

Low

959243

S25A3
Solute carrier family 25 member 3

1

0

Small-scale

0.249

Low

1140900

FBX31
F-box only protein 31

1

0

Small-scale

0.249

Low

1173980

CREG2
Protein CREG2

1

0

Small-scale

0.249

Low

1173984

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024