Protein: NPM3
Nucleoplasmin-3

Gene: NPM3
Organism: Homo sapiens
Interactions: 249
UniProt ID: O75607

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

271250

NPM
Nucleophosmin

8

6

Small-scale

0.975

High

271352

NPM2
Nucleoplasmin-2

4

8

High-throughput

0.909

High

271289

RL15
Large ribosomal subunit protein eL15

3

1

High-throughput

0.675

High

271342

NEPRO
Nucleolus and neural progenitor protein

3

1

High-throughput

0.675

High

271461

LAS1L
Ribosomal biogenesis protein LAS1L

3

1

High-throughput

0.675

High

271312

RL6
Large ribosomal subunit protein eL6

3

2

High-throughput

0.667

High

271314

KPCZ
Protein kinase C zeta type

3

7

High-throughput

0.633

High

271234

SRP72
Signal recognition particle subunit SRP72

2

1

High-throughput

0.628

High

271256

RL17
Large ribosomal subunit protein uL22

2

2

High-throughput

0.628

High

271267

RL13A
Large ribosomal subunit protein uL13

2

2

High-throughput

0.628

High

271269

KI67
Proliferation marker protein Ki-67

2

5

High-throughput

0.628

High

271292

RS8
Small ribosomal subunit protein eS8

2

1

High-throughput

0.628

High

271294

RL23A
Large ribosomal subunit protein uL23

2

1

High-throughput

0.628

High

271321

BOP1
Ribosome biogenesis protein BOP1

2

4

High-throughput

0.628

High

271339

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

2

1

High-throughput

0.628

High

271341

RL7L
Ribosomal protein uL30-like

2

3

High-throughput

0.628

High

271360

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

2

2

High-throughput

0.628

High

271371

BRX1
Ribosome biogenesis protein BRX1 homolog

2

8

High-throughput

0.628

High

271384

SENP5
Sentrin-specific protease 5

2

3

High-throughput

0.628

High

271391

POP1
Ribonucleases P/MRP protein subunit POP1

2

1

High-throughput

0.628

High

271394

EBP2
Probable rRNA-processing protein EBP2

2

1

High-throughput

0.628

High

271400

WDR18
WD repeat-containing protein 18

2

7

High-throughput

0.628

High

271404

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

2

3

High-throughput

0.628

High

271406

WDR12
Ribosome biogenesis protein WDR12

2

8

High-throughput

0.628

High

271411

SENP3
Sentrin-specific protease 3

2

3

High-throughput

0.628

High

271422

E41L5
Band 4.1-like protein 5

2

4

High-throughput

0.628

High

271436

TEX10
Testis-expressed protein 10

2

1

High-throughput

0.628

High

271453

MAGD2
Melanoma-associated antigen D2

2

2

High-throughput

0.628

High

271288

RS3A
Small ribosomal subunit protein eS1

2

4

High-throughput

0.611

High

271442

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

1

High-throughput

0.611

High

271322

RRP1B
Ribosomal RNA processing protein 1 homolog B

2

4

High-throughput

0.601

High

271235

RECQ4
ATP-dependent DNA helicase Q4

2

6

High-throughput

0.584

High

271244

MYC
Myc proto-oncogene protein

2

4

High-throughput

0.584

High

271295

RS6
Small ribosomal subunit protein eS6

2

2

High-throughput

0.584

High

271381

UPP
Uracil phosphoribosyltransferase homolog

2

0

High-throughput

0.580

High

271245

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

271246

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

5

High-throughput

0.571

High

271272

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

6

High-throughput

0.571

High

271311

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

6

High-throughput

0.571

High

131352

IMA4
Importin subunit alpha-4

1

4

High-throughput

0.536

High

132070

PESC
Pescadillo homolog

1

1

High-throughput

0.536

High

133098

MPP10
U3 small nucleolar ribonucleoprotein protein MPP10

1

1

High-throughput

0.536

High

172321

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.536

High

177427

NVL
Nuclear valosin-containing protein-like

1

3

High-throughput

0.536

High

195998

RRP8
Ribosomal RNA-processing protein 8

1

1

High-throughput

0.536

High

229992

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

1

High-throughput

0.536

High

269583

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

10

High-throughput

0.536

High

271231

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

271232

RPP40
Ribonuclease P protein subunit p40

1

1

High-throughput

0.536

High

271233

RL1D1
Ribosomal L1 domain-containing protein 1

1

4

High-throughput

0.536

High

271238

RPP14
Ribonuclease P protein subunit p14

1

1

High-throughput

0.536

High

271239

NSA2
Ribosome biogenesis protein NSA2 homolog

1

1

High-throughput

0.536

High

271240

NET1
Netrin-1

1

1

High-throughput

0.536

High

271241

RPP29
Ribonuclease P protein subunit p29

1

1

High-throughput

0.536

High

271242

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

10

High-throughput

0.536

High

271243

NSD2
Histone-lysine N-methyltransferase NSD2

1

6

High-throughput

0.536

High

271247

RLA2
Large ribosomal subunit protein P2

1

1

High-throughput

0.536

High

271248

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.536

High

271252

H2AX
Histone H2AX

1

8

High-throughput

0.536

High

271253

YBOX3
Y-box-binding protein 3

1

4

High-throughput

0.536

High

271254

ZNF16
Zinc finger protein 16

1

7

High-throughput

0.536

High

271255

ZNF22
Zinc finger protein 22

1

5

High-throughput

0.536

High

271257

NUCL
Nucleolin

1

3

High-throughput

0.536

High

271261

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.536

High

271262

RL10
Large ribosomal subunit protein uL16

1

2

High-throughput

0.536

High

271264

RL9
Large ribosomal subunit protein uL6

1

1

High-throughput

0.536

High

271265

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.536

High

271268

RBM34
RNA-binding protein 34

1

3

High-throughput

0.536

High

271270

NOP2
Probable 28S rRNA

1

3

High-throughput

0.536

High

271273

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.536

High

271274

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

271275

RS9
Small ribosomal subunit protein uS4

1

3

High-throughput

0.536

High

271277

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.536

High

271279

CTCF
Transcriptional repressor CTCF

1

8

High-throughput

0.536

High

271282

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.536

High

271284

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

3

High-throughput

0.536

High

271285

PRD15
PR domain zinc finger protein 15

1

8

High-throughput

0.536

High

271287

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.536

High

271290

RL27
Large ribosomal subunit protein eL27

1

2

High-throughput

0.536

High

271291

RL37A
Large ribosomal subunit protein eL43

1

1

High-throughput

0.536

High

271298

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.536

High

271300

RL10A
Large ribosomal subunit protein uL1

1

3

High-throughput

0.536

High

271301

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.536

High

271302

RL11
Large ribosomal subunit protein uL5

1

1

High-throughput

0.536

High

271303

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.536

High

271304

RPP38
Ribonuclease P protein subunit p38

1

1

High-throughput

0.536

High

271305

RPP30
Ribonuclease P protein subunit p30

1

1

High-throughput

0.536

High

271307

RL19
Large ribosomal subunit protein eL19

1

2

High-throughput

0.536

High

271308

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.536

High

271313

CEBPZ
CCAAT/enhancer-binding protein zeta

1

1

High-throughput

0.536

High

271315

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.536

High

271316

DDX10
Probable ATP-dependent RNA helicase DDX10

1

9

High-throughput

0.536

High

271317

SRSF5
Serine/arginine-rich splicing factor 5

1

3

High-throughput

0.536

High

271320

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.536

High

271323

BMS1
Ribosome biogenesis protein BMS1 homolog

1

2

High-throughput

0.536

High

271324

RRS1
Ribosome biogenesis regulatory protein homolog

1

1

High-throughput

0.536

High

271325

WDR43
WD repeat-containing protein 43

1

8

High-throughput

0.536

High

271326

TTF1
Transcription termination factor 1

1

1

High-throughput

0.536

High

271327

PUM3
Pumilio homolog 3

1

1

High-throughput

0.536

High

271328

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

1

High-throughput

0.536

High

271329

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

1

1

High-throughput

0.536

High

271332

GLYR1
Cytokine-like nuclear factor N-PAC

1

4

High-throughput

0.536

High

271335

PDCD4
Programmed cell death protein 4

1

3

High-throughput

0.536

High

271336

GLE1
mRNA export factor GLE1

1

2

High-throughput

0.536

High

271343

CC137
Coiled-coil domain-containing protein 137

1

1

High-throughput

0.536

High

271344

WDR74
WD repeat-containing protein 74

1

8

High-throughput

0.536

High

271350

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

4

High-throughput

0.536

High

271351

CENPV
Centromere protein V

1

1

High-throughput

0.536

High

271353

KTN1
Kinectin

1

4

High-throughput

0.536

High

271356

RIOX2
Ribosomal oxygenase 2

1

3

High-throughput

0.536

High

271357

RM41
Large ribosomal subunit protein mL41

1

1

High-throughput

0.536

High

271358

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

2

High-throughput

0.536

High

271361

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

4

High-throughput

0.536

High

271362

RP25L
Ribonuclease P protein subunit p25-like protein

1

3

High-throughput

0.536

High

271363

DDX51
ATP-dependent RNA helicase DDX51

1

12

High-throughput

0.536

High

271364

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.536

High

271366

HJURP
Holliday junction recognition protein

1

1

High-throughput

0.536

High

271368

PAPD5
Terminal nucleotidyltransferase 4B

1

3

High-throughput

0.536

High

271369

WDR36
WD repeat-containing protein 36

1

6

High-throughput

0.536

High

271370

DDX54
ATP-dependent RNA helicase DDX54

1

6

High-throughput

0.536

High

271373

NOC3L
Nucleolar complex protein 3 homolog

1

3

High-throughput

0.536

High

271375

RT27
Small ribosomal subunit protein mS27

1

1

High-throughput

0.536

High

271380

RM24
Large ribosomal subunit protein uL24m

1

1

High-throughput

0.536

High

271383

DDX27
Probable ATP-dependent RNA helicase DDX27

1

6

High-throughput

0.536

High

271389

F111A
Serine protease FAM111A

1

1

High-throughput

0.536

High

271392

ZN184
Zinc finger protein 184

1

5

High-throughput

0.536

High

271395

DDX50
ATP-dependent RNA helicase DDX50

1

5

High-throughput

0.536

High

271396

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.536

High

271397

CG050
Uncharacterized protein C7orf50

1

1

High-throughput

0.536

High

271398

NOL10
Nucleolar protein 10

1

1

High-throughput

0.536

High

271399

RPP25
Ribonuclease P protein subunit p25

1

3

High-throughput

0.536

High

271401

MAK16
Protein MAK16 homolog

1

1

High-throughput

0.536

High

271402

RM20
Large ribosomal subunit protein bL20m

1

1

High-throughput

0.536

High

271405

GTPB4
GTP-binding protein 4

1

3

High-throughput

0.536

High

271407

REXO4
RNA exonuclease 4

1

3

High-throughput

0.536

High

271408

DDX24
ATP-dependent RNA helicase DDX24

1

7

High-throughput

0.536

High

271409

NAT10
RNA cytidine acetyltransferase

1

1

High-throughput

0.536

High

271410

E41LB
Band 4.1-like protein 4B

1

5

High-throughput

0.536

High

271413

ZN768
Zinc finger protein 768

1

4

High-throughput

0.536

High

271414

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

1

1

High-throughput

0.536

High

271415

RIOX1
Ribosomal oxygenase 1

1

3

High-throughput

0.536

High

271416

WDR55
WD repeat-containing protein 55

1

7

High-throughput

0.536

High

271417

RPF2
Ribosome production factor 2 homolog

1

1

High-throughput

0.536

High

271418

DDX31
ATP-dependent DNA helicase DDX31

1

9

High-throughput

0.536

High

271419

RPF1
Ribosome production factor 1

1

4

High-throughput

0.536

High

271420

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

1

High-throughput

0.536

High

271425

SSF1
Suppressor of SWI4 1 homolog

1

1

High-throughput

0.536

High

271426

TF7L2
Transcription factor 7-like 2

1

5

High-throughput

0.536

High

271427

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.536

High

271428

PNO1
RNA-binding protein PNO1

1

1

High-throughput

0.536

High

271429

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

3

High-throughput

0.536

High

271430

DDX18
ATP-dependent RNA helicase DDX18

1

11

High-throughput

0.536

High

271431

SDA1
Protein SDA1 homolog

1

1

High-throughput

0.536

High

271432

NLE1
Notchless protein homolog 1

1

5

High-throughput

0.536

High

271433

RBM28
RNA-binding protein 28

1

3

High-throughput

0.536

High

271435

PK1IP
p21-activated protein kinase-interacting protein 1

1

8

High-throughput

0.536

High

271437

AATF
Protein AATF

1

1

High-throughput

0.536

High

271438

DDX56
Probable ATP-dependent RNA helicase DDX56

1

8

High-throughput

0.536

High

271439

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.536

High

271440

TAP26
Thyroid transcription factor 1-associated protein 26

1

1

High-throughput

0.536

High

271445

ZNF70
Zinc finger protein 70

1

4

High-throughput

0.536

High

271447

NOL12
Nucleolar protein 12

1

1

High-throughput

0.536

High

271448

RLP24
Probable ribosome biogenesis protein RLP24

1

2

High-throughput

0.536

High

271449

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

271452

SCML1
Sex comb on midleg-like protein 1

1

1

High-throughput

0.536

High

271455

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

1

High-throughput

0.536

High

271458

NOP16
Nucleolar protein 16

1

1

High-throughput

0.536

High

271459

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.536

High

271460

NOC2L
Nucleolar complex protein 2 homolog

1

1

High-throughput

0.536

High

271463

RT18B
Small ribosomal subunit protein mS40

1

1

High-throughput

0.536

High

271443

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.518

High

271263

RL12
Large ribosomal subunit protein uL11

1

0

High-throughput

0.513

High

271337

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

1

0

High-throughput

0.513

High

271359

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.513

High

271378

POP5
Ribonuclease P/MRP protein subunit POP5

1

0

High-throughput

0.513

High

271387

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.513

High

271424

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.513

High

271451

UTP16
U3 small nucleolar RNA-associated protein NOL7

1

0

High-throughput

0.513

High

271462

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

271258

WT1
Wilms tumor protein

1

4

High-throughput

0.508

High

271271

CRK
Adapter molecule crk

1

2

High-throughput

0.501

High

271286

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.501

High

196546

ZBT24
Zinc finger and BTB domain-containing protein 24

1

8

High-throughput

0.489

High

271251

H2A1
Histone H2A type 1

1

7

High-throughput

0.489

High

271259

H1T
Histone H1t

1

5

High-throughput

0.489

High

271331

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

271338

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

High-throughput

0.489

High

271345

ZN574
Zinc finger protein 574

1

8

High-throughput

0.489

High

271355

H2A2B
Histone H2A type 2-B

1

7

High-throughput

0.489

High

271365

ZFP62
Zinc finger protein 62 homolog

1

7

High-throughput

0.489

High

271382

NSUN4
5-methylcytosine rRNA methyltransferase NSUN4

1

3

High-throughput

0.489

High

271386

ZN668
Zinc finger protein 668

1

9

High-throughput

0.489

High

271388

ZN512
Zinc finger protein 512

1

10

High-throughput

0.489

High

271423

RM47
Large ribosomal subunit protein uL29m

1

1

High-throughput

0.489

High

271441

NHSL3
NHS-like protein 3

1

4

High-throughput

0.489

High

271444

ZN624
Zinc finger protein 624

1

5

High-throughput

0.489

High

271456

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.489

High

271457

RRP15
RRP15-like protein

1

1

High-throughput

0.489

High

271348

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.480

High

122409

MEN1
Menin

1

1

High-throughput

0.479

High

182485

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

267813

EED
Polycomb protein EED

1

8

High-throughput

0.479

High

271236

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

271237

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

271266

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

271276

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.479

High

271280

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

271281

CDK9
Cyclin-dependent kinase 9

1

4

High-throughput

0.479

High

271293

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

271296

H4
Histone H4

1

2

High-throughput

0.479

High

271297

H2B1C
Histone H2B type 1-C/E/F/G/I

1

5

High-throughput

0.479

High

271299

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

271306

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

271309

EWS
RNA-binding protein EWS

1

2

High-throughput

0.479

High

271318

TIF1B
Transcription intermediary factor 1-beta

1

6

High-throughput

0.479

High

271319

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

271330

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

271333

LARP7
La-related protein 7

1

9

High-throughput

0.479

High

271334

MIDN
Midnolin

1

1

High-throughput

0.479

High

271340

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

271346

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

271347

H32
Histone H3.2

1

5

Small-scale

0.479

High

271349

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.479

High

271354

ZCH18
Zinc finger CCCH domain-containing protein 18

1

5

High-throughput

0.479

High

271372

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

271376

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

271377

KAT6A
Histone acetyltransferase KAT6A

1

4

High-throughput

0.479

High

271379

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.479

High

271385

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

271390

CIC
Protein capicua homolog

1

5

High-throughput

0.479

High

271393

BARD1
BRCA1-associated RING domain protein 1

1

3

High-throughput

0.479

High

271412

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

271421

SP110
Sp110 nuclear body protein

1

9

High-throughput

0.479

High

271434

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.479

High

271446

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

271450

FZR1
Fizzy-related protein homolog

1

8

High-throughput

0.479

High

271454

RL26L
Ribosomal protein uL24-like

1

1

High-throughput

0.479

High

271260

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

271278

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

271374

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

90054

D6RAT0
Small ribosomal subunit protein eS1

1

4

High-throughput

0.445

High

101618

F8VR69
Ribosomal protein L6

1

2

High-throughput

0.445

High

271249

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

271310

HEN1
Helix-loop-helix protein 1

1

1

High-throughput

0.437

High

271403

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

64131

ZN729
Zinc finger protein 729

1

5

High-throughput

0.407

High

203078

P52K
52 kDa repressor of the inhibitor of the protein kinase

1

0

High-throughput

0.279

Low

271283

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.279

Low

271367

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024