Protein: PKD2
Polycystin-2 (PC2) (Autosomal dominant polycystic kidney disease type II protein) (Polycystic kidney disease 2 protein) (Polycystwin) (R48321) (Transient receptor potential cation channel subfamily P member 2)

Gene: PKD2
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q13563

Gene Ontology (top 5):
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0001889 - liver development
GO:0001892 - embryonic placenta development
GO:0001947 - heart looping
GO:0002133 - polycystin complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957575

PKD1
Polycystin-1

8

10

Small-scale

0.982

High

1039381

PKD2
Polycystin-2

7

15

Small-scale

0.980

High

823174

TRPC1
Short transient receptor potential channel 1

2

18

Small-scale

0.825

High

1039413

PK2L2
Polycystin-2-like protein 2

2

14

High-throughput

0.811

High

1039392

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

2

0

High-throughput

0.770

High

1039384

CNGA3
Cyclic nucleotide-gated channel alpha-3

1

2

High-throughput

0.691

High

1039395

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

2

High-throughput

0.691

High

1039411

PICK1
PRKCA-binding protein

3

3

High-throughput

0.667

High

1039400

BCAS4
Breast carcinoma-amplified sequence 4

3

0

High-throughput

0.638

High

1039419

ALG5
Dolichyl-phosphate beta-glucosyltransferase

3

0

High-throughput

0.638

High

793181

PI2R
Prostacyclin receptor

2

1

High-throughput

0.628

High

989614

ACHD
Acetylcholine receptor subunit delta

2

1

High-throughput

0.628

High

1039415

CRYL1
Lambda-crystallin homolog

2

1

High-throughput

0.628

High

1039390

CE170
Centrosomal protein of 170 kDa

2

8

High-throughput

0.611

High

67064

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.606

High

237971

EXOC3
Exocyst complex component 3

2

0

High-throughput

0.602

High

1039394

TMPSC
Transmembrane protease serine 12

2

0

High-throughput

0.602

High

616628

GLRA2
Glycine receptor subunit alpha-2

2

0

High-throughput

0.585

High

253002

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1039387

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1039409

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

584295

TNNI3
Troponin I, cardiac muscle

1

2

Small-scale

0.573

High

889469

KR108
Keratin-associated protein 10-8

1

3

High-throughput

0.573

High

1039391

K1C40
Keratin, type I cytoskeletal 40

1

8

High-throughput

0.573

High

170070

PLS1
Phospholipid scramblase 1

1

0

High-throughput

0.549

High

161061

CLGN
Calmegin

1

1

High-throughput

0.536

High

233982

NMD3B
Glutamate receptor ionotropic, NMDA 3B

1

1

High-throughput

0.536

High

598733

S1PR1
Sphingosine 1-phosphate receptor 1

1

3

High-throughput

0.536

High

600760

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

1

High-throughput

0.536

High

677591

NTR1
Neurotensin receptor type 1

1

1

High-throughput

0.536

High

833591

NUMB
Protein numb homolog

1

1

High-throughput

0.536

High

1039402

RN133
E3 ubiquitin-protein ligase RNF133

1

2

High-throughput

0.536

High

1039418

VATD
V-type proton ATPase subunit D

1

1

High-throughput

0.536

High

970567

ID2
DNA-binding protein inhibitor ID-2

1

1

Small-scale

0.529

High

64152

IFM5
Interferon-induced transmembrane protein 5

1

0

High-throughput

0.513

High

847942

CP2J2
Cytochrome P450 2J2

1

0

High-throughput

0.513

High

949219

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.513

High

1039382

C1D
Nuclear nucleic acid-binding protein C1D

1

0

High-throughput

0.513

High

1039383

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1039388

CLM2
CMRF35-like molecule 2

1

0

High-throughput

0.513

High

1039389

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1039393

TMC4
Transmembrane channel-like protein 4

1

0

High-throughput

0.513

High

1039397

LSME2
Leucine-rich single-pass membrane protein 2

1

0

High-throughput

0.513

High

1039398

OR6T1
Olfactory receptor 6T1

1

0

High-throughput

0.513

High

1039399

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

0

High-throughput

0.513

High

1039401

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

1039403

NAR4
Ecto-ADP-ribosyltransferase 4

1

0

High-throughput

0.513

High

1039404

DACT3
Dapper homolog 3

1

0

High-throughput

0.513

High

1039406

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

1039410

CENPH
Centromere protein H

1

0

High-throughput

0.513

High

1039414

FBX2
F-box only protein 2

1

0

High-throughput

0.513

High

1039417

O10H1
Olfactory receptor 10H1

1

0

High-throughput

0.513

High

1039420

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.513

High

359920

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

5

High-throughput

0.481

High

617110

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

8

Small-scale

0.481

High

888862

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.481

High

205368

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

237594

DIAP1
Protein diaphanous homolog 1

1

1

Small-scale

0.479

High

438758

SRPRA
Signal recognition particle receptor subunit alpha

1

1

High-throughput

0.479

High

681834

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.479

High

1039396

GCC2
GRIP and coiled-coil domain-containing protein 2

1

3

High-throughput

0.479

High

1039412

TM248
Transmembrane protein 248

1

1

High-throughput

0.479

High

390870

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

1039408

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

118298

HAX1
HCLS1-associated protein X-1

1

0

Small-scale

0.438

High

1039407

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.426

High

1039405

FAM3D
Protein FAM3D

3

0

High-throughput

0.345

High

1039416

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.328

High

795956

MAGA8
Melanoma-associated antigen 8

2

0

High-throughput

0.327

High

1039385

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1039386

CO032
Uncharacterized protein C15orf32

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024