Protein: TNPO2
Transportin-2 (Karyopherin beta-2b)

Gene: TNPO2
Organism: Homo sapiens
Interactions: 189
UniProt ID: O14787

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006606 - protein import into nucleus
GO:0008139 - nuclear localization sequence binding
GO:0031267 - small GTPase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155560

RAN
GTP-binding nuclear protein Ran

4

18

Small-scale

0.897

High

155571

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

3

High-throughput

0.811

High

155569

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

3

High-throughput

0.783

High

155570

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

3

High-throughput

0.783

High

155576

IMB1
Importin subunit beta-1

1

9

High-throughput

0.691

High

155621

TMA16
Translation machinery-associated protein 16

3

2

High-throughput

0.667

High

155497

XRP2
Protein XRP2

3

4

High-throughput

0.656

High

155579

MICA
MHC class I polypeptide-related sequence A

3

1

High-throughput

0.656

High

155663

TN13B
Tumor necrosis factor ligand superfamily member 13B

3

7

High-throughput

0.656

High

155500

KLHL2
Kelch-like protein 2

2

2

High-throughput

0.628

High

155656

NXF1
Nuclear RNA export factor 1

2

6

Small-scale

0.624

High

155639

Q9H4D1
Protein kinase

1

3

High-throughput

0.621

High

155512

H2A1B
Histone H2A type 1-B/E

1

6

High-throughput

0.618

High

155517

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

7

High-throughput

0.618

High

129993

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.613

High

155661

FZD10
Frizzled-10

2

2

High-throughput

0.611

High

155667

RNF11
RING finger protein 11

2

4

High-throughput

0.611

High

155492

GSC2
Homeobox protein goosecoid-2

2

1

High-throughput

0.606

High

155537

GCH1
GTP cyclohydrolase 1

2

1

High-throughput

0.606

High

155562

PO6F2
POU domain, class 6, transcription factor 2

2

6

High-throughput

0.606

High

155578

SF01
Splicing factor 1

2

3

High-throughput

0.606

High

155601

RBM45
RNA-binding protein 45

2

8

High-throughput

0.606

High

155620

BIRC7
Baculoviral IAP repeat-containing protein 7

2

8

High-throughput

0.606

High

155633

TRIM8
E3 ubiquitin-protein ligase TRIM8

2

6

High-throughput

0.606

High

155646

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

1

High-throughput

0.606

High

155622

MTNB
Methylthioribulose-1-phosphate dehydratase

2

0

High-throughput

0.601

High

155495

SCN2B
Sodium channel subunit beta-2

3

11

High-throughput

0.599

High

155501

LYPD3
Ly6/PLAUR domain-containing protein 3

3

1

High-throughput

0.599

High

155542

CD68
Macrosialin

3

1

High-throughput

0.599

High

155596

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

8

High-throughput

0.599

High

155602

TARG1
Trafficking regulator of GLUT4 1

3

2

High-throughput

0.599

High

155624

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

7

High-throughput

0.599

High

155653

PD1L1
Programmed cell death 1 ligand 1

3

18

High-throughput

0.599

High

155662

CAH14
Carbonic anhydrase 14

3

8

High-throughput

0.599

High

155558

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.590

High

155507

EGFR
Epidermal growth factor receptor

2

11

Small-scale

0.584

High

155604

PNKD
Probable hydrolase PNKD

2

4

High-throughput

0.584

High

155642

WDR76
WD repeat-containing protein 76

2

9

High-throughput

0.584

High

155514

FUMH
Fumarate hydratase, mitochondrial

2

0

High-throughput

0.580

High

155538

OTX2
Homeobox protein OTX2

2

0

High-throughput

0.580

High

155561

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.580

High

155566

TBX2
T-box transcription factor TBX2

2

0

High-throughput

0.580

High

155573

BLMH
Bleomycin hydrolase

2

0

High-throughput

0.580

High

155634

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

2

0

High-throughput

0.580

High

155658

SRTD3
SERTA domain-containing protein 3

2

0

High-throughput

0.580

High

155660

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

2

0

High-throughput

0.580

High

155521

NDKA
Nucleoside diphosphate kinase A

1

2

High-throughput

0.573

High

155519

TAU
Microtubule-associated protein tau

2

10

High-throughput

0.571

High

155554

TERF1
Telomeric repeat-binding factor 1

1

3

High-throughput

0.568

High

58410

F234B
Protein FAM234B

2

5

High-throughput

0.558

High

155513

GLPB
Glycophorin-B

2

4

High-throughput

0.558

High

155515

ACM4
Muscarinic acetylcholine receptor M4

2

7

High-throughput

0.558

High

155522

CD44
CD44 antigen

2

1

High-throughput

0.558

High

155528

EPHA1
Ephrin type-A receptor 1

2

6

High-throughput

0.558

High

155531

EDNRB
Endothelin receptor type B

2

3

High-throughput

0.558

High

155535

5HT2C
5-hydroxytryptamine receptor 2C

2

6

High-throughput

0.558

High

155551

BCAM
Basal cell adhesion molecule

2

2

High-throughput

0.558

High

155557

FCGRN
IgG receptor FcRn large subunit p51

2

1

High-throughput

0.558

High

155564

CD83
CD83 antigen

2

1

High-throughput

0.558

High

155587

VASN
Vasorin

2

3

High-throughput

0.558

High

155589

TM108
Transmembrane protein 108

2

1

High-throughput

0.558

High

155591

DLK2
Protein delta homolog 2

2

5

High-throughput

0.558

High

155599

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

8

High-throughput

0.558

High

155606

SIGL1
SIGLEC family-like protein 1

2

6

High-throughput

0.558

High

155610

F174A
Membrane protein FAM174A

2

5

High-throughput

0.558

High

155641

PACC1
Proton-activated chloride channel

2

5

High-throughput

0.558

High

155643

LRRC4
Leucine-rich repeat-containing protein 4

2

3

High-throughput

0.558

High

155504

K2C75
Keratin, type II cytoskeletal 75

2

1

High-throughput

0.553

High

155648

PDLI7
PDZ and LIM domain protein 7

2

18

High-throughput

0.553

High

155649

ANM8
Protein arginine N-methyltransferase 8

2

1

High-throughput

0.553

High

155657

KLHL3
Kelch-like protein 3

2

2

High-throughput

0.553

High

148133

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.553

High

155503

SIX3
Homeobox protein SIX3

1

2

High-throughput

0.536

High

155518

TACD2
Tumor-associated calcium signal transducer 2

1

2

High-throughput

0.536

High

155526

S1PR1
Sphingosine 1-phosphate receptor 1

1

4

High-throughput

0.536

High

155547

RANG
Ran-specific GTPase-activating protein

1

20

High-throughput

0.536

High

155550

NU153
Nuclear pore complex protein Nup153

1

20

High-throughput

0.536

High

155563

EFNB1
Ephrin-B1

1

6

High-throughput

0.536

High

155577

SUZ12
Polycomb protein SUZ12

1

2

High-throughput

0.536

High

155607

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.536

High

155613

AQP3
Aquaporin-3

1

5

High-throughput

0.536

High

155630

OVOL2
Transcription factor Ovo-like 2

1

20

High-throughput

0.536

High

155627

PNMA5
Paraneoplastic antigen-like protein 5

1

5

High-throughput

0.523

High

155527

5NTD
5'-nucleotidase

1

0

High-throughput

0.517

High

155496

TP4A3
Protein tyrosine phosphatase type IVA 3

1

20

High-throughput

0.515

High

2745

A0A0C4DGF1
Zinc finger and BTB domain containing 32

1

1

High-throughput

0.515

High

155616

KLK6
Kallikrein-6

1

4

High-throughput

0.515

High

155671

V9HW27
Alpha-crystallin B chain

1

2

High-throughput

0.515

High

155516

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

155520

PVR
Poliovirus receptor

1

0

High-throughput

0.513

High

155597

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.513

High

155623

SNF8
Vacuolar-sorting protein SNF8

1

0

High-throughput

0.513

High

155544

RL4
Large ribosomal subunit protein uL4

1

5

Small-scale

0.501

High

155553

NUP98
Nuclear pore complex protein Nup98-Nup96

1

20

Small-scale

0.501

High

155645

A1CF
APOBEC1 complementation factor

1

4

Small-scale

0.501

High

126557

P2Y10
Putative P2Y purinoceptor 10

1

20

High-throughput

0.489

High

155493

CYB5B
Cytochrome b5 type B

1

2

High-throughput

0.489

High

155499

VAMP5
Vesicle-associated membrane protein 5

1

2

High-throughput

0.489

High

155502

MPZL1
Myelin protein zero-like protein 1

1

11

High-throughput

0.489

High

155510

GLPA
Glycophorin-A

1

4

High-throughput

0.489

High

155529

DRD4
D(4) dopamine receptor

1

7

High-throughput

0.489

High

155533

TNR5
Tumor necrosis factor receptor superfamily member 5

1

12

High-throughput

0.489

High

155536

V2R
Vasopressin V2 receptor

1

10

High-throughput

0.489

High

155540

CD70
CD70 antigen

1

2

High-throughput

0.489

High

155541

CD80
T-lymphocyte activation antigen CD80

1

18

High-throughput

0.489

High

155543

BASI
Basigin

1

11

High-throughput

0.489

High

155545

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

2

High-throughput

0.489

High

155552

EFNA4
Ephrin-A4

1

6

High-throughput

0.489

High

155555

ARSF
Arylsulfatase F

1

1

High-throughput

0.489

High

155556

PAR2
Proteinase-activated receptor 2

1

18

High-throughput

0.489

High

155568

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

18

High-throughput

0.489

High

155574

MAP7
Ensconsin

1

11

High-throughput

0.489

High

155575

FXYD3
FXYD domain-containing ion transport regulator 3

1

2

High-throughput

0.489

High

155590

BTNL9
Butyrophilin-like protein 9

1

4

High-throughput

0.489

High

155595

ARMX6
Protein ARMCX6

1

4

High-throughput

0.489

High

155626

OPALI
Opalin

1

2

High-throughput

0.489

High

155629

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

5

High-throughput

0.489

High

155636

FXYD6
FXYD domain-containing ion transport regulator 6

1

2

High-throughput

0.489

High

155637

F234A
Protein FAM234A

1

5

High-throughput

0.489

High

155638

UN93B
Protein unc-93 homolog B1

1

5

High-throughput

0.489

High

155647

GPR84
G-protein coupled receptor 84

1

10

High-throughput

0.489

High

155654

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.489

High

155668

GPR45
Probable G-protein coupled receptor 45

1

11

High-throughput

0.489

High

155669

NPTN
Neuroplastin

1

10

High-throughput

0.489

High

155509

CRYAB
Alpha-crystallin B chain

1

2

High-throughput

0.481

High

155625

BIRC8
Baculoviral IAP repeat-containing protein 8

1

8

High-throughput

0.481

High

155665

KLH20
Kelch-like protein 20

1

3

High-throughput

0.481

High

155666

ZBT32
Zinc finger and BTB domain-containing protein 32

1

20

High-throughput

0.481

High

155530

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

11

High-throughput

0.479

High

155532

BRD2
Bromodomain-containing protein 2

1

13

High-throughput

0.479

High

155534

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

155559

H4
Histone H4

1

5

High-throughput

0.479

High

155565

KIF23
Kinesin-like protein KIF23

1

10

High-throughput

0.479

High

155567

G3BP1
Ras GTPase-activating protein-binding protein 1

1

7

High-throughput

0.479

High

155572

CUL3
Cullin-3

1

9

High-throughput

0.479

High

155584

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.479

High

155592

DPPA3
Developmental pluripotency-associated protein 3

1

2

High-throughput

0.479

High

155594

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

155614

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

155617

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.479

High

155640

PKHA4
Pleckstrin homology domain-containing family A member 4

1

17

High-throughput

0.479

High

155651

TLS1
Splicing factor C9orf78

1

6

High-throughput

0.479

High

155664

R3HD2
R3H domain-containing protein 2

1

2

High-throughput

0.479

High

155670

NEMO
NF-kappa-B essential modulator

1

2

Small-scale

0.479

High

155631

Q9BS75
KLHL20 protein

1

3

High-throughput

0.470

High

155491

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

155525

TAL1
T-cell acute lymphocytic leukemia protein 1

1

0

High-throughput

0.458

High

155583

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

155652

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.458

High

155505

PTBP3
Polypyrimidine tract-binding protein 3

1

4

High-throughput

0.445

High

155582

CD158
Coiled-coil domain-containing protein 158

1

1

High-throughput

0.439

High

126185

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

0

High-throughput

0.438

High

155194

NRP1
Neuropilin-1

1

2

High-throughput

0.437

High

155511

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.437

High

155546

PE2R3
Prostaglandin E2 receptor EP3 subtype

1

8

High-throughput

0.437

High

155548

LPAR6
Lysophosphatidic acid receptor 6

1

18

High-throughput

0.437

High

155580

AR13B
ADP-ribosylation factor-like protein 13B

1

1

High-throughput

0.437

High

155585

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.437

High

155586

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

10

High-throughput

0.437

High

155608

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

10

High-throughput

0.437

High

155612

DCAF4
DDB1- and CUL4-associated factor 4

1

3

High-throughput

0.437

High

155615

LAR4B
La-related protein 4B

1

2

High-throughput

0.437

High

155644

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

5

High-throughput

0.437

High

155650

SLX9
Ribosome biogenesis protein SLX9 homolog

1

1

Small-scale

0.437

High

155549

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.408

High

155539

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

2

0

High-throughput

0.316

High

155581

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.316

High

155598

RDIC1
Regulator of DNA class I crossover intermediates 1

2

0

High-throughput

0.316

High

155600

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

155605

BEND7
BEN domain-containing protein 7

2

0

High-throughput

0.316

High

155609

THAP6
THAP domain-containing protein 6

2

0

High-throughput

0.316

High

155619

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

2

0

High-throughput

0.316

High

155632

FUCO2
Plasma alpha-L-fucosidase

2

0

High-throughput

0.316

High

155588

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

68032

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

155494

SNG1
Synaptogyrin-1

1

0

High-throughput

0.279

Low

155498

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

155508

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.279

Low

155523

LEUK
Leukosialin

1

0

High-throughput

0.279

Low

155524

DPEP1
Dipeptidase 1

1

0

High-throughput

0.279

Low

155603

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

155618

P2RX5
P2X purinoceptor 5

1

0

High-throughput

0.279

Low

155628

TR13C
Tumor necrosis factor receptor superfamily member 13C

1

0

High-throughput

0.279

Low

155635

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

155655

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

155659

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

155593

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.249

Low

155611

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.249

Low

155506

TCL1B
T-cell leukemia/lymphoma protein 1B

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024