Protein: DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (EC 2.7.12.1) (Minibrain-related kinase) (Mirk protein kinase)

Gene: DYR1B, DYRK1B
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q9Y463

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity
GO:0004713 - protein tyrosine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

568843

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

2

17

High-throughput

0.811

High

590241

CCNA2
Cyclin-A2

2

20

High-throughput

0.811

High

952902

FOXK1
Forkhead box protein K1

2

10

High-throughput

0.811

High

1268313

ZN516
Zinc finger protein 516

2

3

High-throughput

0.811

High

805496

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

20

Small-scale

0.806

High

432392

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.789

High

438648

HS90B
Heat shock protein HSP 90-beta

2

20

High-throughput

0.789

High

1082660

MK14
Mitogen-activated protein kinase 14

2

19

Small-scale

0.768

High

903063

DCAF7
DDB1- and CUL4-associated factor 7

10

20

Small-scale

0.758

High

659097

MK01
Mitogen-activated protein kinase 1

1

17

Small-scale

0.735

High

498382

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

8

High-throughput

0.726

High

1348462

FA53C
Protein FAM53C

5

2

High-throughput

0.722

High

1026253

PAK1
Serine/threonine-protein kinase PAK 1

1

20

High-throughput

0.698

High

260405

ZN217
Zinc finger protein 217

1

3

High-throughput

0.691

High

625652

CDK2
Cyclin-dependent kinase 2

1

17

High-throughput

0.691

High

861999

PLK1
Serine/threonine-protein kinase PLK1

1

20

High-throughput

0.691

High

1028457

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

20

Small-scale

0.691

High

1035069

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

19

High-throughput

0.691

High

1082467

DDB1
DNA damage-binding protein 1

1

3

High-throughput

0.691

High

1134669

KIF24
Kinesin-like protein KIF24

1

13

High-throughput

0.691

High

1069576

TEBP
Prostaglandin E synthase 3

3

7

High-throughput

0.675

High

1241783

RN169
E3 ubiquitin-protein ligase RNF169

3

4

Small-scale

0.667

High

1310236

LZTS2
Leucine zipper putative tumor suppressor 2

5

20

High-throughput

0.666

High

414404

RB
Retinoblastoma-associated protein

2

14

High-throughput

0.657

High

660172

RBL1
Retinoblastoma-like protein 1

2

14

High-throughput

0.657

High

1017071

TROAP
Tastin

4

1

High-throughput

0.648

High

1377781

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

17

Small-scale

0.647

High

1158434

F117B
Protein FAM117B

4

5

High-throughput

0.643

High

595964

HNF1A
Hepatocyte nuclear factor 1-alpha

2

8

Small-scale

0.637

High

126181

BMAL1
Basic helix-loop-helix ARNT-like protein 1

2

4

High-throughput

0.628

High

881350

CTBP2
C-terminal-binding protein 2

2

11

High-throughput

0.628

High

928539

DYL1
Dynein light chain 1, cytoplasmic

2

4

High-throughput

0.628

High

997144

RBL2
Retinoblastoma-like protein 2

2

14

High-throughput

0.628

High

999248

EP300
Histone acetyltransferase p300

2

16

High-throughput

0.628

High

1135375

ATD3B
ATPase family AAA domain-containing protein 3B

2

11

High-throughput

0.628

High

1266631

LPIN2
Phosphatidate phosphatase LPIN2

2

6

High-throughput

0.628

High

1268568

K0232
Uncharacterized protein KIAA0232

2

1

High-throughput

0.628

High

1270845

CBP
CREB-binding protein

2

16

High-throughput

0.628

High

1296860

EP400
E1A-binding protein p400

2

4

High-throughput

0.628

High

1356357

AKA11
A-kinase anchor protein 11

2

1

High-throughput

0.628

High

1377783

ARIP4
Helicase ARIP4

2

10

High-throughput

0.628

High

229151

PRKN
E3 ubiquitin-protein ligase parkin

1

15

High-throughput

0.618

High

1078204

MK11
Mitogen-activated protein kinase 11

1

19

Small-scale

0.618

High

1329785

HIPK2
Homeodomain-interacting protein kinase 2

1

20

Small-scale

0.618

High

181013

GSC2
Homeobox protein goosecoid-2

2

6

High-throughput

0.606

High

1301842

RANB9
Ran-binding protein 9

1

14

Small-scale

0.594

High

230558

LZTS3
Leucine zipper putative tumor suppressor 3

2

20

High-throughput

0.574

High

1170395

PPR3F
Protein phosphatase 1 regulatory subunit 3F

2

1

High-throughput

0.574

High

1174499

CEFIP
Cardiac-enriched FHL2-interacting protein

2

1

High-throughput

0.574

High

1202293

GLCI1
Glucocorticoid-induced transcript 1 protein

2

5

High-throughput

0.574

High

1217927

MISP
Mitotic interactor and substrate of PLK1

2

1

High-throughput

0.574

High

1318740

F117A
Protein FAM117A

2

5

High-throughput

0.574

High

1350321

SI1L2
Signal-induced proliferation-associated 1-like protein 2

2

11

High-throughput

0.574

High

970616

ID2
DNA-binding protein inhibitor ID-2

1

6

Small-scale

0.561

High

900091

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

1

Small-scale

0.552

High

1327955

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

1

Small-scale

0.552

High

230289

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

13

High-throughput

0.536

High

262134

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.536

High

521319

SKI
Ski oncogene

1

4

High-throughput

0.536

High

657457

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.536

High

850246

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

16

High-throughput

0.536

High

952784

SKOR1
SKI family transcriptional corepressor 1

1

4

High-throughput

0.536

High

1032708

CTBP1
C-terminal-binding protein 1

1

11

High-throughput

0.536

High

1101041

RFX7
DNA-binding protein RFX7

1

3

High-throughput

0.536

High

1145675

ICE2
Little elongation complex subunit 2

1

1

High-throughput

0.536

High

1333263

KAT8
Histone acetyltransferase KAT8

1

4

High-throughput

0.536

High

1348795

TECR
Very-long-chain enoyl-CoA reductase

1

2

High-throughput

0.536

High

1356921

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.536

High

1377199

ICE1
Little elongation complex subunit 1

1

2

High-throughput

0.536

High

1377782

TRRAP
Transformation/transcription domain-associated protein

1

8

High-throughput

0.536

High

1256730

ARH40
Rho guanine nucleotide exchange factor 40

2

4

High-throughput

0.521

High

1235318

MS3L1
MSL complex subunit 3

1

0

High-throughput

0.513

High

1357903

HDAC5
Histone deacetylase 5

1

10

Small-scale

0.501

High

196536

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

11

High-throughput

0.489

High

1176357

KNDC1
Kinase non-catalytic C-lobe domain-containing protein 1

1

15

High-throughput

0.489

High

1237906

ENAH
Protein enabled homolog

1

13

High-throughput

0.489

High

1299568

FACOS
FANCD2 opposite strand protein

1

1

High-throughput

0.489

High

1342219

WDR6
tRNA

1

20

High-throughput

0.489

High

684420

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

790909

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

15

High-throughput

0.479

High

910197

1433E
14-3-3 protein epsilon

1

15

High-throughput

0.479

High

1060980

IMB1
Importin subunit beta-1

1

4

High-throughput

0.479

High

1069244

TCAL1
Transcription elongation factor A protein-like 1

1

1

High-throughput

0.479

High

1260968

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

1296550

EGLN2
Prolyl hydroxylase EGLN2

1

6

Small-scale

0.479

High

1301016

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1357486

CHIP
E3 ubiquitin-protein ligase CHIP

1

12

High-throughput

0.479

High

65047

P121C
Nuclear envelope pore membrane protein POM 121C

1

15

High-throughput

0.445

High

709127

MCM7
DNA replication licensing factor MCM7

1

7

Small-scale

0.445

High

1236879

ARF
Tumor suppressor ARF

1

1

High-throughput

0.445

High

72776

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

10

High-throughput

0.437

High

1101394

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

1169928

PKHG7
Pleckstrin homology domain-containing family G member 7

1

9

High-throughput

0.437

High

1299927

PKH4B
Pleckstrin homology domain-containing family G member 4B

1

6

High-throughput

0.437

High

1299811

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

8

High-throughput

0.407

High

215500

SCO2
Protein SCO2 homolog, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024