Protein: DOCK6
Dedicator of cytokinesis protein 6

Gene: DOCK6
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q96HP0

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0007264 - small GTPase-mediated signal transduction
GO:0048471 - perinuclear region of cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1244070

DOCK8
Dedicator of cytokinesis protein 8

3

11

High-throughput

0.871

High

1293664

DOCK7
Dedicator of cytokinesis protein 7

3

11

High-throughput

0.861

High

1293663

LRCH3
DISP complex protein LRCH3

5

12

High-throughput

0.716

High

1044509

RAB32
Ras-related protein Rab-32

1

5

High-throughput

0.691

High

895227

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.656

High

1185492

MOB1B
MOB kinase activator 1B

2

11

High-throughput

0.621

High

1293667

MOB1A
MOB kinase activator 1A

2

11

High-throughput

0.621

High

845163

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.618

High

925518

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1293670

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

3

12

High-throughput

0.593

High

66692

ZN785
Zinc finger protein 785

2

2

High-throughput

0.574

High

122068

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

0

High-throughput

0.547

High

176838

EIF3D
Eukaryotic translation initiation factor 3 subunit D

2

0

High-throughput

0.547

High

1293672

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

2

0

High-throughput

0.547

High

264515

LRCH4
Leucine-rich repeat and calponin homology domain-containing protein 4

2

12

High-throughput

0.543

High

528388

MYH6
Myosin-6

1

1

High-throughput

0.536

High

1216618

CRLF3
Cytokine receptor-like factor 3

1

2

High-throughput

0.536

High

1284760

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

275282

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

500855

CLUS
Clusterin

1

0

High-throughput

0.513

High

1138362

CBPC6
Cytosolic carboxypeptidase 6

1

0

High-throughput

0.513

High

1293665

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.513

High

476202

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

1052924

FLNC
Filamin-C

1

0

High-throughput

0.493

High

215372

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

2

High-throughput

0.489

High

1101524

KIF7
Kinesin-like protein KIF7

1

1

High-throughput

0.489

High

1151810

ISM2
Isthmin-2

1

1

High-throughput

0.489

High

1293668

RTN4
Reticulon-4

1

2

High-throughput

0.489

High

163143

XPO1
Exportin-1

1

3

High-throughput

0.479

High

982379

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1035543

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.479

High

1061558

CUL7
Cullin-7

1

3

High-throughput

0.479

High

1219359

CUL9
Cullin-9

1

3

High-throughput

0.479

High

1293671

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.470

High

718102

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

440671

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.437

High

1044046

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.437

High

1138578

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

12

High-throughput

0.437

High

1166858

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

1171237

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1174281

MOB3C
MOB kinase activator 3C

1

11

High-throughput

0.437

High

1293666

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.437

High

240136

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.407

High

1293669

ZN331
Zinc finger protein 331

2

0

High-throughput

0.328

High

489791

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

0

High-throughput

0.298

High

126845

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.279

Low

961777

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.279

Low

1048450

LRP8
Low-density lipoprotein receptor-related protein 8

1

0

High-throughput

0.279

Low

1104168

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

0

High-throughput

0.269

Low

241063

RT14
Small ribosomal subunit protein uS14m

1

0

High-throughput

0.249

Low

262544

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

266410

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024