Protein: SNX18
Sorting nexin-18 (SH3 and PX domain-containing protein 3B)

Gene: SNX18
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q96RF0

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0009898 - cytoplasmic side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924801

GRB2
Growth factor receptor-bound protein 2

5

20

High-throughput

0.716

High

1261042

SNX33
Sorting nexin-33

1

18

High-throughput

0.691

High

275222

GRAP2
GRB2-related adapter protein 2

3

20

High-throughput

0.667

High

167002

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

6

High-throughput

0.640

High

160723

AURKA
Aurora kinase A

4

7

High-throughput

0.638

High

555182

CD44
CD44 antigen

2

1

High-throughput

0.628

High

713135

SDC2
Syndecan-2

2

1

High-throughput

0.628

High

840797

DYN2
Dynamin-2

1

14

Small-scale

0.618

High

992490

SOS1
Son of sevenless homolog 1

1

3

Small-scale

0.618

High

992517

SOS2
Son of sevenless homolog 2

1

3

Small-scale

0.618

High

1300849

SNX18
Sorting nexin-18

1

16

Small-scale

0.618

High

1300858

SNX9
Sorting nexin-9

1

17

Small-scale

0.618

High

1300859

SNX8
Sorting nexin-8

1

16

Small-scale

0.618

High

71003

ZBT42
Zinc finger and BTB domain-containing protein 42

2

6

High-throughput

0.606

High

1216901

RELL1
RELT-like protein 1

2

0

High-throughput

0.602

High

815707

TNFL6
Tumor necrosis factor ligand superfamily member 6

2

2

Small-scale

0.601

High

67299

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

995158

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.580

High

1022971

CDC16
Cell division cycle protein 16 homolog

2

3

High-throughput

0.574

High

182195

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

3

High-throughput

0.571

High

152323

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

19

Small-scale

0.561

High

1300852

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

3

Small-scale

0.561

High

267539

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

2

2

High-throughput

0.553

High

991651

KRA11
Keratin-associated protein 1-1

2

1

High-throughput

0.553

High

1087928

PTN21
Tyrosine-protein phosphatase non-receptor type 21

2

2

High-throughput

0.553

High

1183756

DPPA4
Developmental pluripotency-associated protein 4

2

2

High-throughput

0.553

High

1300855

ABI2
Abl interactor 2

2

14

High-throughput

0.553

High

228425

PRKN
E3 ubiquitin-protein ligase parkin

1

11

High-throughput

0.553

High

1034718

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

19

Small-scale

0.536

High

245205

RAMP1
Receptor activity-modifying protein 1

1

1

High-throughput

0.536

High

672723

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.536

High

1041155

CUL1
Cullin-1

1

3

High-throughput

0.536

High

1251891

RIN3
Ras and Rab interactor 3

1

3

High-throughput

0.536

High

1300856

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

13

High-throughput

0.536

High

1294839

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

3

Small-scale

0.515

High

578230

LAG3
Lymphocyte activation gene 3 protein

1

0

High-throughput

0.513

High

729160

K22E
Keratin, type II cytoskeletal 2 epidermal

1

0

High-throughput

0.513

High

957918

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

1300851

RFIP5
Rab11 family-interacting protein 5

1

0

Small-scale

0.505

High

306279

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

3

Small-scale

0.501

High

941716

ADAM8
Disintegrin and metalloproteinase domain-containing protein 8

1

19

Small-scale

0.501

High

312957

SLU7
Pre-mRNA-splicing factor SLU7

1

1

High-throughput

0.489

High

509978

VDR
Vitamin D3 receptor

1

4

High-throughput

0.489

High

520087

BMP2
Bone morphogenetic protein 2

1

3

High-throughput

0.489

High

1241289

ZN784
Zinc finger protein 784

1

2

High-throughput

0.489

High

1241829

ZBT44
Zinc finger and BTB domain-containing protein 44

1

4

High-throughput

0.489

High

1300853

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.489

High

323024

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

610487

CBL
E3 ubiquitin-protein ligase CBL

1

1

Small-scale

0.479

High

944518

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

19

Small-scale

0.479

High

967373

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

1146754

A16L1
Autophagy-related protein 16-1

1

3

Small-scale

0.479

High

1291688

BICD1
Protein bicaudal D homolog 1

1

4

High-throughput

0.479

High

391852

H2A1B
Histone H2A type 1-B/E

1

0

High-throughput

0.458

High

882515

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

5

High-throughput

0.445

High

1300854

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.438

High

163168

XPO1
Exportin-1

1

6

High-throughput

0.437

High

244816

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.437

High

246606

MCE1
mRNA-capping enzyme

1

4

High-throughput

0.437

High

631556

BRD2
Bromodomain-containing protein 2

1

6

High-throughput

0.437

High

652012

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

721213

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

779950

CCNF
Cyclin-F

1

1

High-throughput

0.437

High

818372

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

1044075

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.437

High

1171327

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1236450

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.437

High

1300857

ARI1
E3 ubiquitin-protein ligase ARIH1

1

10

High-throughput

0.437

High

989070

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.417

High

718124

BMI1
Polycomb complex protein BMI-1

1

6

High-throughput

0.407

High

1293103

ZN764
Zinc finger protein 764

2

0

High-throughput

0.328

High

253165

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

1080889

HSPB2
Heat shock protein beta-2

2

0

High-throughput

0.316

High

1118907

MSS51
Putative protein MSS51 homolog, mitochondrial

2

0

High-throughput

0.316

High

1235780

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

2

0

High-throughput

0.316

High

1300850

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

785683

ASIP
Agouti-signaling protein

1

0

High-throughput

0.279

Low

921399

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.279

Low

929039

SKP1
S-phase kinase-associated protein 1

1

0

High-throughput

0.279

Low

991112

PIGF
Phosphatidylinositol-glycan biosynthesis class F protein

1

0

High-throughput

0.279

Low

1083637

ZNF74
Zinc finger protein 74

1

0

High-throughput

0.279

Low

1191834

CE024
UPF0461 protein C5orf24

1

0

High-throughput

0.279

Low

1204453

FBX11
F-box only protein 11

1

0

High-throughput

0.279

Low

1109349

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

1168820

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.249

Low

1219635

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.249

Low

275462

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

High-throughput

0.232

Low

1233157

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024