Protein: FANCA
Fanconi anemia group A protein (Protein FACA)

Gene: FANCA
Organism: Homo sapiens
Interactions: 167
UniProt ID: O15360

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

174326

FANCG
Fanconi anemia group G protein

53

2

Small-scale

0.772

High

176615

FANCM
Fanconi anemia group M protein

12

1

Small-scale

0.756

High

176584

FANCC
Fanconi anemia group C protein

33

0

Small-scale

0.736

High

176645

FANCF
Fanconi anemia group F protein

23

0

Small-scale

0.733

High

176643

FANCE
Fanconi anemia group E protein

15

0

Small-scale

0.727

High

176647

FANCL
E3 ubiquitin-protein ligase FANCL

15

0

Small-scale

0.727

High

176609

FAP20
Fanconi anemia core complex-associated protein 20

11

0

Small-scale

0.727

High

176620

FANCB
Fanconi anemia group B protein

7

0

Small-scale

0.714

High

176511

FANCA
Fanconi anemia group A protein

8

0

Small-scale

0.709

High

176591

FP100
Fanconi anemia core complex-associated protein 100

5

0

Small-scale

0.684

High

176577

BLM
RecQ-like DNA helicase BLM

5

0

Small-scale

0.678

High

176596

TOP3A
DNA topoisomerase 3-alpha

5

0

Small-scale

0.676

High

176567

BRCA1
Breast cancer type 1 susceptibility protein

3

0

Small-scale

0.654

High

176554

RFA1
Replication protein A 70 kDa DNA-binding subunit

4

0

Small-scale

0.648

High

176599

SPTN1
Spectrin alpha chain, non-erythrocytic 1

3

1

Small-scale

0.643

High

176634

FAP24
Fanconi anemia core complex-associated protein 24

3

0

Small-scale

0.628

High

176558

AKT1
RAC-alpha serine/threonine-protein kinase

2

1

Small-scale

0.625

High

158347

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

2

Small-scale

0.617

High

67721

CENPX
Centromere protein X

3

0

Small-scale

0.613

High

176617

CENPS
Centromere protein S

3

0

Small-scale

0.613

High

176636

FACD2
Fanconi anemia group D2 protein

3

0

Small-scale

0.613

High

167418

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

2

2

Small-scale

0.606

High

176575

SMCA4
Transcription activator BRG1

2

0

Small-scale

0.606

High

176595

CTBP1
C-terminal-binding protein 1

2

0

Small-scale

0.593

High

176602

HES1
Transcription factor HES-1

2

0

Small-scale

0.593

High

176535

HS90A
Heat shock protein HSP 90-alpha

2

2

Small-scale

0.586

High

176526

SPTA1
Spectrin alpha chain, erythrocytic 1

2

2

Small-scale

0.584

High

176593

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

1

Small-scale

0.578

High

176562

OPRM
Mu-type opioid receptor

2

3

High-throughput

0.574

High

176563

APJ
Apelin receptor

2

3

High-throughput

0.574

High

176573

NPY2R
Neuropeptide Y receptor type 2

2

2

High-throughput

0.574

High

176576

NEK2
Serine/threonine-protein kinase Nek2

1

2

Small-scale

0.573

High

160259

AURKA
Aurora kinase A

1

1

Small-scale

0.561

High

176530

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.559

High

176561

CTNB1
Catenin beta-1

2

0

Small-scale

0.559

High

176642

RMI1
RecQ-mediated genome instability protein 1

2

0

Small-scale

0.559

High

176614

P2RY8
P2Y purinoceptor 8

2

6

High-throughput

0.558

High

176585

CENPE
Centromere-associated protein E

1

0

Small-scale

0.549

High

176551

FPR1
fMet-Leu-Phe receptor

1

4

High-throughput

0.536

High

176566

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

176579

CXCR4
C-X-C chemokine receptor type 4

1

4

High-throughput

0.536

High

176534

CAN1
Calpain-1 catalytic subunit

1

0

Small-scale

0.529

High

176658

SNX5
Sorting nexin-5

1

0

Small-scale

0.529

High

149802

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

176522

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

176586

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.513

High

176603

IKBB
NF-kappa-B inhibitor beta

1

0

High-throughput

0.513

High

176605

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

176608

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

176610

PLBL1
Phospholipase B-like 1

1

0

High-throughput

0.513

High

176626

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

176629

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

176633

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

176637

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

176638

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

176646

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

176657

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

126559

P2Y10
Putative P2Y purinoceptor 10

1

6

High-throughput

0.489

High

171883

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.489

High

176557

V2R
Vasopressin V2 receptor

1

2

High-throughput

0.489

High

176594

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.489

High

176631

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.489

High

176654

GPR55
G-protein coupled receptor 55

1

7

High-throughput

0.489

High

176660

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

176661

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

116944

SGK1
Serine/threonine-protein kinase Sgk1

1

1

Small-scale

0.481

High

176548

TCPA
T-complex protein 1 subunit alpha

1

1

Small-scale

0.481

High

176574

TCPG
T-complex protein 1 subunit gamma

1

1

Small-scale

0.481

High

159113

CSKP
Peripheral plasma membrane protein CASK

1

0

High-throughput

0.480

High

176597

ATR
Serine/threonine-protein kinase ATR

1

0

Small-scale

0.480

High

176512

MSH5
MutS protein homolog 5

1

1

Small-scale

0.479

High

176514

XRCC3
DNA repair protein XRCC3

1

2

Small-scale

0.479

High

176519

RA51D
DNA repair protein RAD51 homolog 4

1

2

Small-scale

0.479

High

176529

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.479

High

176537

HS90B
Heat shock protein HSP 90-beta

1

2

Small-scale

0.479

High

176541

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.479

High

176543

ENPL
Endoplasmin

1

2

Small-scale

0.479

High

176545

NCK1
SH2/SH3 adapter protein NCK1

1

4

High-throughput

0.479

High

176559

MCM5
DNA replication licensing factor MCM5

1

1

Small-scale

0.479

High

176560

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.479

High

176568

MSH2
DNA mismatch repair protein Msh2

1

1

Small-scale

0.479

High

176570

CRK
Adapter molecule crk

1

3

High-throughput

0.479

High

176582

GRB2
Growth factor receptor-bound protein 2

1

3

High-throughput

0.479

High

176588

RAD51
DNA repair protein RAD51 homolog 1

1

2

Small-scale

0.479

High

176619

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

Small-scale

0.479

High

176624

XPF
DNA repair endonuclease XPF

1

1

Small-scale

0.479

High

176640

SIK2
Serine/threonine-protein kinase SIK2

1

1

Small-scale

0.479

High

176662

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

1

Small-scale

0.479

High

154705

TCRG1
Transcription elongation regulator 1

1

0

Small-scale

0.460

High

157395

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

0

Small-scale

0.460

High

161748

AZIN1
Antizyme inhibitor 1

1

0

Small-scale

0.460

High

176523

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

Small-scale

0.460

High

176527

ALDOA
Fructose-bisphosphate aldolase A

1

0

Small-scale

0.460

High

176528

K2C1
Keratin, type II cytoskeletal 1

1

0

Small-scale

0.460

High

176531

ATPB
ATP synthase subunit beta, mitochondrial

1

0

Small-scale

0.460

High

176532

ENOA
Alpha-enolase

1

0

Small-scale

0.460

High

176542

TCTP
Translationally-controlled tumor protein

1

0

Small-scale

0.460

High

176547

ZNF24
Zinc finger protein 24

1

0

Small-scale

0.460

High

176550

MX1
Interferon-induced GTP-binding protein Mx1

1

0

Small-scale

0.460

High

176553

DNJB1
DnaJ homolog subfamily B member 1

1

0

Small-scale

0.460

High

176556

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.460

High

176569

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

Small-scale

0.460

High

176581

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

Small-scale

0.460

High

176589

RL18
Large ribosomal subunit protein eL18

1

0

Small-scale

0.460

High

176592

TAF10
Transcription initiation factor TFIID subunit 10

1

0

Small-scale

0.460

High

176600

DX39B
Spliceosome RNA helicase DDX39B

1

0

Small-scale

0.460

High

176623

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

Small-scale

0.460

High

176635

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

0

Small-scale

0.460

High

176650

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.460

High

176656

NUB1
NEDD8 ultimate buster 1

1

0

Small-scale

0.460

High

122372

MEN1
Menin

1

0

Small-scale

0.458

High

176513

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

176516

PRKN
E3 ubiquitin-protein ligase parkin

1

0

Small-scale

0.458

High

176517

HUS1
Checkpoint protein HUS1

1

0

Small-scale

0.458

High

176518

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

176520

REC8
Meiotic recombination protein REC8 homolog

1

0

Small-scale

0.458

High

176533

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

176538

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.458

High

176540

PCNA
Proliferating cell nuclear antigen

1

0

Small-scale

0.458

High

176544

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

176546

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.458

High

176549

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.458

High

176552

TBG1
Tubulin gamma-1 chain

1

0

Small-scale

0.458

High

176555

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

High-throughput

0.458

High

176565

DDIT3
DNA damage-inducible transcript 3 protein

1

0

Small-scale

0.458

High

176571

NOTC1
Neurogenic locus notch homolog protein 1

1

0

Small-scale

0.458

High

176572

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

0

Small-scale

0.458

High

176578

PER3
Period circadian protein homolog 3

1

0

Small-scale

0.458

High

176580

H4
Histone H4

1

0

High-throughput

0.458

High

176583

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

Small-scale

0.458

High

176587

SUH
Recombining binding protein suppressor of hairless

1

0

Small-scale

0.458

High

176598

TDG
G/T mismatch-specific thymine DNA glycosylase

1

0

Small-scale

0.458

High

176607

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

176611

BRAT1
BRCA1-associated ATM activator 1

1

0

Small-scale

0.458

High

176613

DPOLN
DNA polymerase nu

1

0

Small-scale

0.458

High

176616

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

Small-scale

0.458

High

176621

SMCR8
Guanine nucleotide exchange protein SMCR8

1

0

Small-scale

0.458

High

176622

CTF18
Chromosome transmission fidelity protein 18 homolog

1

0

Small-scale

0.458

High

176625

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

0

Small-scale

0.458

High

176627

RMI2
RecQ-mediated genome instability protein 2

1

0

Small-scale

0.458

High

176628

DDX11
ATP-dependent DNA helicase DDX11

1

0

Small-scale

0.458

High

176632

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

Small-scale

0.458

High

176644

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

0

Small-scale

0.458

High

176651

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

176655

TRAF6
TNF receptor-associated factor 6

1

0

Small-scale

0.458

High

176515

PRKY
Putative serine/threonine-protein kinase PRKY

1

2

High-throughput

0.445

High

176564

BASI
Basigin

1

1

High-throughput

0.437

High

176601

SPIDR
DNA repair-scaffolding protein

1

0

Small-scale

0.426

High

176652

TTC7A
Tetratricopeptide repeat protein 7A

1

0

Small-scale

0.426

High

176536

ACM4
Muscarinic acetylcholine receptor M4

2

0

High-throughput

0.328

High

176606

CF118
Uncharacterized protein C6orf118

2

0

High-throughput

0.328

High

176604

AMZ1
Archaemetzincin-1

1

0

High-throughput

0.279

Low

176618

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

176630

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

176639

DNAI2
Dynein axonemal intermediate chain 2

1

0

High-throughput

0.279

Low

176641

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low

176649

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

176653

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.279

Low

176521

DUS4L
tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like

1

0

Small-scale

0.251

Low

176539

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

Small-scale

0.251

Low

176659

LIPG
Endothelial lipase

1

0

Small-scale

0.251

Low

176612

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

176524

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

176525

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.232

Low

176590

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

176648

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024