Protein: FANCC
Fanconi anemia group C protein (Protein FACC)

Gene: FANCC
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q00597

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0002262 - myeloid cell homeostasis
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

174380

FANCG
Fanconi anemia group G protein

9

1

Small-scale

0.745

High

176584

FANCA
Fanconi anemia group A protein

33

0

Small-scale

0.736

High

960710

FANCE
Fanconi anemia group E protein

15

0

Small-scale

0.731

High

960712

FANCF
Fanconi anemia group F protein

8

0

Small-scale

0.714

High

960686

CTBP1
C-terminal-binding protein 1

4

0

Small-scale

0.661

High

960697

FANCM
Fanconi anemia group M protein

4

0

Small-scale

0.657

High

538198

ENPL
Endoplasmin

2

2

Small-scale

0.651

High

960688

SPTN1
Spectrin alpha chain, non-erythrocytic 1

3

1

Small-scale

0.650

High

786309

STAT1
Signal transducer and activator of transcription 1-alpha/beta

3

0

Small-scale

0.636

High

714186

HSP74
Heat shock 70 kDa protein 4

2

1

Small-scale

0.624

High

960714

FANCL
E3 ubiquitin-protein ligase FANCL

3

0

Small-scale

0.613

High

414866

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.598

High

503903

HSP7C
Heat shock cognate 71 kDa protein

2

0

Small-scale

0.598

High

448319

GSTP1
Glutathione S-transferase P

2

1

Small-scale

0.586

High

960693

FAP20
Fanconi anemia core complex-associated protein 20

2

0

Small-scale

0.585

High

960699

FANCB
Fanconi anemia group B protein

2

0

Small-scale

0.585

High

960701

STMN2
Stathmin-2

2

1

Small-scale

0.584

High

560190

NCPR
NADPH--cytochrome P450 reductase

1

1

Small-scale

0.581

High

960719

ZBT32
Zinc finger and BTB domain-containing protein 32

2

0

Small-scale

0.561

High

585445

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

2

0

Small-scale

0.559

High

716998

CTNB1
Catenin beta-1

2

0

Small-scale

0.559

High

960683

FP100
Fanconi anemia core complex-associated protein 100

2

0

Small-scale

0.559

High

960707

FACD2
Fanconi anemia group D2 protein

2

0

Small-scale

0.559

High

348620

RASN
GTPase NRas

1

1

High-throughput

0.541

High

350081

RASK
GTPase KRas

1

1

High-throughput

0.541

High

622430

CCND1
G1/S-specific cyclin-D1

1

1

High-throughput

0.541

High

739951

TGFR2
TGF-beta receptor type-2

1

1

High-throughput

0.541

High

869867

PMS2
Mismatch repair endonuclease PMS2

1

1

High-throughput

0.541

High

960681

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

1

High-throughput

0.541

High

960711

CAN10
Calpain-10

1

1

High-throughput

0.541

High

960717

MLH3
DNA mismatch repair protein Mlh3

1

1

High-throughput

0.541

High

636305

DNJB1
DnaJ homolog subfamily B member 1

1

0

Small-scale

0.537

High

358496

CO1A1
Collagen alpha-1(I) chain

1

1

High-throughput

0.536

High

562915

STMN1
Stathmin

1

1

Small-scale

0.527

High

211002

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

0

High-throughput

0.518

High

338287

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.518

High

414248

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.518

High

522914

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.518

High

626098

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

787206

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.518

High

960687

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.518

High

960702

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.518

High

960705

RHG07
Rho GTPase-activating protein 7

1

0

High-throughput

0.518

High

960718

MUTYH
Adenine DNA glycosylase

1

0

High-throughput

0.518

High

848833

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.513

High

960690

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.513

High

960713

SPS2L
SPATS2-like protein

1

0

High-throughput

0.513

High

960715

SLTM
SAFB-like transcription modulator

1

0

High-throughput

0.513

High

738331

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.494

High

71098

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.493

High

960708

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.493

High

436028

CO1A2
Collagen alpha-2(I) chain

1

1

High-throughput

0.489

High

431744

HS90A
Heat shock protein HSP 90-alpha

1

2

Small-scale

0.481

High

837931

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.481

High

306110

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

Small-scale

0.479

High

360637

SPTA1
Spectrin alpha chain, erythrocytic 1

1

1

Small-scale

0.479

High

427878

CAN1
Calpain-1 catalytic subunit

1

1

Small-scale

0.479

High

891082

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

2

Small-scale

0.479

High

960695

Q6PK50
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

960709

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

2

Small-scale

0.479

High

154783

TCRG1
Transcription elongation regulator 1

1

0

Small-scale

0.460

High

161755

AZIN1
Antizyme inhibitor 1

1

0

Small-scale

0.460

High

380594

K2C1
Keratin, type II cytoskeletal 1

1

0

Small-scale

0.460

High

590165

CCNA2
Cyclin-A2

1

0

Small-scale

0.460

High

670931

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

0

Small-scale

0.460

High

870755

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

Small-scale

0.460

High

898274

RS3A
Small ribosomal subunit protein eS1

1

0

Small-scale

0.460

High

960680

FANCC
Fanconi anemia group C protein

1

0

Small-scale

0.460

High

960682

RL18
Large ribosomal subunit protein eL18

1

0

Small-scale

0.460

High

960685

RED
Protein Red

1

0

Small-scale

0.460

High

960700

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

0

Small-scale

0.460

High

67728

CENPX
Centromere protein X

1

0

Small-scale

0.458

High

227184

PRKN
E3 ubiquitin-protein ligase parkin

1

0

Small-scale

0.458

High

418176

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

749379

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

804207

NOTC1
Neurogenic locus notch homolog protein 1

1

0

Small-scale

0.458

High

960689

HES1
Transcription factor HES-1

1

0

Small-scale

0.458

High

960698

CENPS
Centromere protein S

1

0

Small-scale

0.458

High

960692

Q6FHY5
MEOX2 protein

1

2

High-throughput

0.457

High

960703

Q96BE0
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.437

High

960696

UNC5A
Netrin receptor UNC5A

1

0

Small-scale

0.288

High

960684

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

0

High-throughput

0.282

High

960691

PGFRL
Platelet-derived growth factor receptor-like protein

1

0

High-throughput

0.282

High

960704

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.279

Low

960706

TMM43
Transmembrane protein 43

1

0

High-throughput

0.279

Low

960716

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

342168

ATP6
ATP synthase subunit a

1

0

Small-scale

0.251

Low

960694

EBLN2
Endogenous Bornavirus-like nucleoprotein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024