Protein: DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial (EC 1.1.1.-) (Dicarbonyl reductase HEP27) (Protein D) (Short chain dehydrogenase/reductase family 25C member 1) (Protein SDR25C1)

Gene: DHRS2
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q13268

Gene Ontology (top 5):
GO:0004090 - carbonyl reductase (NADPH) activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578842

SDC1
Syndecan-1

2

2

High-throughput

0.628

High

555138

CD44
CD44 antigen

2

0

High-throughput

0.602

High

1030131

GMEB1
Glucocorticoid modulatory element-binding protein 1

2

0

High-throughput

0.602

High

713087

SDC2
Syndecan-2

2

2

High-throughput

0.574

High

369531

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

529067

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.571

High

935771

HBB
Hemoglobin subunit beta

2

1

High-throughput

0.549

High

1030106

APBP2
Amyloid protein-binding protein 2

1

0

High-throughput

0.549

High

659655

MZF1
Myeloid zinc finger 1

1

1

High-throughput

0.536

High

679445

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

2

High-throughput

0.536

High

778133

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.536

High

803107

IF2M
Translation initiation factor IF-2, mitochondrial

1

2

High-throughput

0.536

High

1030088

PPCEL
Prolyl endopeptidase-like

1

1

High-throughput

0.536

High

1030116

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

1

High-throughput

0.536

High

1030121

SYTM
Threonine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

1030083

TCEA2
Transcription elongation factor A protein 2

1

0

High-throughput

0.518

High

1030125

EXOS5
Exosome complex component RRP46

1

0

High-throughput

0.518

High

1030133

ZHX2
Zinc fingers and homeoboxes protein 2

1

0

High-throughput

0.518

High

1030117

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.515

High

153914

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

High-throughput

0.513

High

827187

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.513

High

867865

HIRA
Protein HIRA

1

0

High-throughput

0.513

High

1030089

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

0

High-throughput

0.513

High

1030112

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

0

High-throughput

0.513

High

1030113

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.513

High

1030115

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

High-throughput

0.513

High

1030127

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.513

High

154795

TCRG1
Transcription elongation regulator 1

1

0

High-throughput

0.493

High

428579

INVO
Involucrin

1

0

High-throughput

0.493

High

486907

MYBB
Myb-related protein B

1

0

High-throughput

0.493

High

881732

PER3
Period circadian protein homolog 3

1

0

High-throughput

0.493

High

1030082

SAFB2
Scaffold attachment factor B2

1

0

High-throughput

0.493

High

1030086

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.493

High

1030091

AMERL
AMMECR1-like protein

1

0

High-throughput

0.493

High

1030094

FXL19
F-box/LRR-repeat protein 19

1

0

High-throughput

0.493

High

1030095

CC141
Coiled-coil domain-containing protein 141

1

0

High-throughput

0.493

High

1030109

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

1

0

High-throughput

0.493

High

1030110

STMN2
Stathmin-2

1

0

High-throughput

0.493

High

1030119

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.493

High

672661

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

680360

SDC4
Syndecan-4

1

2

High-throughput

0.489

High

1030129

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

338368

EGFR
Epidermal growth factor receptor

1

1

Small-scale

0.479

High

346693

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

374169

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

887546

APC15
Anaphase-promoting complex subunit 15

1

1

High-throughput

0.479

High

1030084

RBBP7
Histone-binding protein RBBP7

1

1

High-throughput

0.479

High

1030085

SMU1
WD40 repeat-containing protein SMU1

1

1

High-throughput

0.479

High

1030101

COP1
E3 ubiquitin-protein ligase COP1

1

2

High-throughput

0.479

High

1030107

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1030124

WDR76
WD repeat-containing protein 76

1

2

High-throughput

0.479

High

1030128

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1030130

PPME1
Protein phosphatase methylesterase 1

1

1

Small-scale

0.479

High

1030132

TACC3
Transforming acidic coiled-coil-containing protein 3

1

2

High-throughput

0.479

High

1030118

MA7D2
MAP7 domain-containing protein 2

1

1

High-throughput

0.470

High

67865

ZN724
Zinc finger protein 724

1

0

High-throughput

0.458

High

125428

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

150977

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

227350

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

322567

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

472854

H2AB2
Histone H2A-Bbd type 2/3

1

0

High-throughput

0.458

High

832422

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

842114

R144A
E3 ubiquitin-protein ligase RNF144A

1

0

Small-scale

0.458

High

921550

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

962761

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1030092

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

1030093

CDC73
Parafibromin

1

0

High-throughput

0.458

High

1030097

DET1
DET1 homolog

1

0

High-throughput

0.458

High

1030103

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1030104

ASB15
Ankyrin repeat and SOCS box protein 15

1

0

High-throughput

0.458

High

1030108

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.458

High

1030111

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1030120

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1030122

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

936035

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.437

High

1030090

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1030099

TEFF1
Tomoregulin-1

3

0

High-throughput

0.347

High

1030105

AP3S1
AP-3 complex subunit sigma-1

2

0

High-throughput

0.328

High

1030098

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

150482

ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3

1

0

High-throughput

0.269

Low

537242

SUIS
Sucrase-isomaltase, intestinal [Cleaved into: Sucrase

1

0

High-throughput

0.269

Low

1030100

PHTF2
Protein PHTF2

1

0

High-throughput

0.269

Low

1030102

DYH3
Dynein axonemal heavy chain 3

1

0

High-throughput

0.269

Low

1030114

FXL18
F-box/LRR-repeat protein 18

1

0

High-throughput

0.269

Low

1030123

ELOV4
Very long chain fatty acid elongase 4

1

0

High-throughput

0.269

Low

1030126

TRM13
tRNA:m(4)X modification enzyme TRM13 homolog

1

0

High-throughput

0.269

Low

353288

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.249

Low

1030087

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

Small-scale

0.249

Low

1030096

ASB18
Ankyrin repeat and SOCS box protein 18

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024