Protein: RN213
E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (ALK lymphoma oligomerization partner on chromosome 17) (E3 ubiquitin-lipopolysaccharide ligase RNF213) (EC 2.3.2.-) (Mysterin) (RING finger protein 213)

Gene: RN213, RNF213
Organism: Homo sapiens
Interactions: 140
UniProt ID: Q63HN8

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002040 - sprouting angiogenesis
GO:0002376 - immune system process
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475903

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

1

Small-scale

0.834

High

932533

UB2L3
Ubiquitin-conjugating enzyme E2 L3

2

2

Small-scale

0.778

High

734655

TRI23
E3 ubiquitin-protein ligase TRIM23

2

0

High-throughput

0.773

High

398003

ISG15
Ubiquitin-like protein ISG15

1

1

Small-scale

0.724

High

896462

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

2

Small-scale

0.713

High

536876

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.702

High

1072357

ELOB
Elongin-B

1

0

High-throughput

0.656

High

895812

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

2

Small-scale

0.647

High

896315

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

3

Small-scale

0.647

High

919751

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

2

High-throughput

0.647

High

1144472

RN213
E3 ubiquitin-protein ligase RNF213

3

1

Small-scale

0.647

High

573743

PTN1
Tyrosine-protein phosphatase non-receptor type 1

3

0

High-throughput

0.638

High

1138877

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

Small-scale

0.621

High

227744

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.618

High

668754

PML
Protein PML

1

1

High-throughput

0.618

High

896124

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.618

High

1144477

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.618

High

488256

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

1

High-throughput

0.611

High

1144476

DLK2
Protein delta homolog 2

2

0

High-throughput

0.602

High

981606

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.549

High

1076426

TRIP6
Thyroid receptor-interacting protein 6

1

0

High-throughput

0.549

High

1132520

UBX11
UBX domain-containing protein 11

1

0

High-throughput

0.549

High

1144474

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.549

High

1144485

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

335125

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

Small-scale

0.537

High

172040

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

598960

FPR1
fMet-Leu-Phe receptor

1

2

High-throughput

0.536

High

726246

BASI
Basigin

1

1

High-throughput

0.536

High

164396

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.517

High

68062

HIDE1
Protein HIDE1

1

0

High-throughput

0.513

High

149656

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.513

High

274239

STK16
Serine/threonine-protein kinase 16

1

0

High-throughput

0.513

High

360035

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

454711

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

631183

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

814260

GLR
Glucagon receptor

1

0

High-throughput

0.513

High

865146

SMTN
Smoothelin

1

0

High-throughput

0.513

High

912483

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

957855

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

1060998

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.513

High

1083570

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

1144478

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1144481

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.513

High

1144482

CPNE8
Copine-8

1

0

High-throughput

0.513

High

1144483

AHNK2
Protein AHNAK2

1

0

High-throughput

0.513

High

1144484

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1144486

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.513

High

1144489

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

1144501

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

0

High-throughput

0.513

High

1144512

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1144518

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.513

High

1144521

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

779582

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

156843

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.489

High

600774

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

1

High-throughput

0.489

High

639596

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.489

High

1059160

CBX2
Chromobox protein homolog 2

1

2

High-throughput

0.489

High

1144523

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

435670

IGF1R
Insulin-like growth factor 1 receptor

1

0

High-throughput

0.479

High

338549

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

434390

TPM2
Tropomyosin beta chain

1

1

High-throughput

0.479

High

438779

SRPRA
Signal recognition particle receptor subunit alpha

1

1

High-throughput

0.479

High

487514

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

572643

VGFR1
Vascular endothelial growth factor receptor 1

1

1

High-throughput

0.479

High

738226

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

1

High-throughput

0.479

High

920987

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

High-throughput

0.479

High

921607

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.479

High

1144488

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.479

High

148933

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

393235

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

High-throughput

0.458

High

651434

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

832520

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

903984

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.458

High

1043051

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1055736

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

0

Small-scale

0.458

High

1066248

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1069701

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.458

High

1085771

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1140525

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1144473

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1144479

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

1144493

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1144495

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1144496

MCRS1
Microspherule protein 1

1

0

High-throughput

0.458

High

1144497

AURKB
Aurora kinase B

1

0

High-throughput

0.458

High

1144500

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

1144504

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1144505

GAN
Gigaxonin

1

0

High-throughput

0.458

High

1144508

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1144510

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

1144511

LYAR
Cell growth-regulating nucleolar protein

1

0

Small-scale

0.458

High

1144514

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1144515

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

1144519

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1144520

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

Small-scale

0.458

High

69755

B1AKQ8
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

2

High-throughput

0.445

High

354477

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.445

High

1144475

Q6IAX9
SRPR protein

1

1

High-throughput

0.445

High

1144506

Q9H932
cDNA FLJ13051 fis, clone NT2RP3001447

1

1

High-throughput

0.445

High

123263

CBX4
E3 SUMO-protein ligase CBX4

1

2

High-throughput

0.437

High

316062

CBX6
Chromobox protein homolog 6

1

2

High-throughput

0.437

High

831898

CEBPD
CCAAT/enhancer-binding protein delta

1

1

High-throughput

0.437

High

1144491

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

529250

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1144499

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1136451

Q5TCU3
Tropomyosin beta chain

1

1

High-throughput

0.407

High

246359

SCN2B
Sodium channel subunit beta-2

3

0

High-throughput

0.347

High

1144502

CD244
Natural killer cell receptor 2B4

3

0

High-throughput

0.347

High

713101

SDC2
Syndecan-2

2

0

High-throughput

0.328

High

1144487

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1144517

LAMP3
Lysosome-associated membrane glycoprotein 3

2

0

High-throughput

0.328

High

994947

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.299

High

1127749

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.282

High

129921

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

0

High-throughput

0.279

Low

131907

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

1030957

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1049976

SCRIB
Protein scribble homolog

1

0

High-throughput

0.279

Low

1101857

S35G1
Solute carrier family 35 member G1

1

0

High-throughput

0.279

Low

1136016

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.279

Low

1144480

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.279

Low

1144490

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1144494

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

0

High-throughput

0.279

Low

1144498

OPALI
Opalin

1

0

High-throughput

0.279

Low

1144503

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1144507

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1144509

NPDC1
Neural proliferation differentiation and control protein 1

1

0

High-throughput

0.279

Low

1144513

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1144516

CLC4A
C-type lectin domain family 4 member A

1

0

High-throughput

0.279

Low

1144522

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

971209

H11
Histone H1.1

1

0

High-throughput

0.269

Low

902626

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.261

Low

205519

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

244562

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.249

Low

297634

RHBT1
Rho-related BTB domain-containing protein 1

1

0

High-throughput

0.249

Low

552933

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

720678

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1144492

ATOH1
Transcription factor ATOH1

1

0

Small-scale

0.249

Low

353948

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

484457

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024