Protein: HEAT3
HEAT repeat-containing protein 3

Gene: HEAT3, HEATR3
Organism: Homo sapiens
Interactions: 169
UniProt ID: Q7Z4Q2

Gene Ontology (top 5):
GO:0006606 - protein import into nucleus
GO:0042273 - ribosomal large subunit biogenesis
GO:0043249 - erythrocyte maturation
GO:0051082 - unfolded protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1190554

TNPO1
Transportin-1

1

0

High-throughput

0.656

High

806065

RL5
Large ribosomal subunit protein uL18

2

0

High-throughput

0.602

High

923088

RL11
Large ribosomal subunit protein uL5

2

0

High-throughput

0.602

High

409786

GLPB
Glycophorin-B

2

1

High-throughput

0.574

High

436929

ACM4
Muscarinic acetylcholine receptor M4

2

1

High-throughput

0.574

High

591226

ACM3
Muscarinic acetylcholine receptor M3

2

1

High-throughput

0.574

High

453443

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

2

High-throughput

0.553

High

1104158

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

3

High-throughput

0.514

High

418411

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

1020476

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

0

High-throughput

0.513

High

198110

MTLR
Motilin receptor

1

1

High-throughput

0.489

High

334230

LDHA
L-lactate dehydrogenase A chain

1

2

High-throughput

0.489

High

362234

GLPA
Glycophorin-A

1

1

High-throughput

0.489

High

403271

LA
Lupus La protein

1

1

High-throughput

0.489

High

422050

LDHB
L-lactate dehydrogenase B chain

1

2

High-throughput

0.489

High

623955

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

1

High-throughput

0.489

High

675193

CLIP1
CAP-Gly domain-containing linker protein 1

1

1

High-throughput

0.489

High

777620

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

856408

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

876001

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

1

High-throughput

0.489

High

957875

EFNB1
Ephrin-B1

1

1

High-throughput

0.489

High

994231

DHX9
ATP-dependent RNA helicase A

1

2

High-throughput

0.489

High

1026080

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

3

High-throughput

0.489

High

1048123

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

2

High-throughput

0.489

High

1092849

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

0.489

High

1190566

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

2

High-throughput

0.489

High

1190568

YTDC2
3'-5' RNA helicase YTHDC2

1

2

High-throughput

0.489

High

681919

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.480

High

260573

TP4A3
Protein tyrosine phosphatase type IVA 3

1

1

High-throughput

0.437

High

879813

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.437

High

1088206

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

1

High-throughput

0.437

High

1116362

LARP7
La-related protein 7

1

2

High-throughput

0.437

High

1140569

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

1130258

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

246362

SCN2B
Sodium channel subunit beta-2

3

0

High-throughput

0.347

High

295738

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

3

0

High-throughput

0.347

High

793120

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

0

High-throughput

0.347

High

1020038

LMAN2
Vesicular integral-membrane protein VIP36

3

0

High-throughput

0.347

High

1074683

SURF2
Surfeit locus protein 2

3

0

High-throughput

0.347

High

1149840

SCAR3
Scavenger receptor class A member 3

3

0

High-throughput

0.347

High

1190541

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

0

High-throughput

0.347

High

1190553

TM171
Transmembrane protein 171

3

0

High-throughput

0.347

High

338629

EGFR
Epidermal growth factor receptor

3

0

Small-scale

0.330

High

600602

EPHA1
Ephrin type-A receptor 1

2

0

High-throughput

0.328

High

658254

5HT2C
5-hydroxytryptamine receptor 2C

2

0

High-throughput

0.328

High

702244

CD70
CD70 antigen

2

0

High-throughput

0.328

High

783669

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

0

High-throughput

0.328

High

1190547

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1190550

UXS1
UDP-glucuronic acid decarboxylase 1

2

0

High-throughput

0.328

High

1190555

TM186
Transmembrane protein 186

2

0

High-throughput

0.328

High

1190569

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.328

High

1190583

FZD10
Frizzled-10

2

0

High-throughput

0.328

High

310307

LYPD3
Ly6/PLAUR domain-containing protein 3

2

0

High-throughput

0.318

High

1190546

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.318

High

1190557

DDRGK
DDRGK domain-containing protein 1

2

0

Small-scale

0.305

High

68071

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

161540

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.279

Low

208608

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.279

Low

210664

NDUB3
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3

1

0

High-throughput

0.279

Low

217573

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

238882

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

242180

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

0

High-throughput

0.279

Low

262871

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.279

Low

300675

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

306410

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low

307392

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

315017

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

316076

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.279

Low

325253

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.279

Low

378547

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.279

Low

454723

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.279

Low

489770

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.279

Low

499402

ESTD
S-formylglutathione hydrolase

1

0

High-throughput

0.279

Low

507627

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

530380

CSPG2
Versican core protein

1

0

High-throughput

0.279

Low

534314

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase

1

0

High-throughput

0.279

Low

542532

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.279

Low

551407

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

1

0

High-throughput

0.279

Low

551756

DESP
Desmoplakin

1

0

High-throughput

0.279

Low

557727

NCK1
SH2/SH3 adapter protein NCK1

1

0

High-throughput

0.279

Low

559796

H12
Histone H1.2

1

0

High-throughput

0.279

Low

579559

ATP5J
ATP synthase-coupling factor 6, mitochondrial

1

0

High-throughput

0.279

Low

594921

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.279

Low

595610

HXA5
Homeobox protein Hox-A5

1

0

High-throughput

0.279

Low

600785

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.279

Low

602117

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.279

Low

676690

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

0

High-throughput

0.279

Low

713109

SDC2
Syndecan-2

1

0

High-throughput

0.279

Low

737390

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.279

Low

744428

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.279

Low

778199

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

815392

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.279

Low

816030

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.279

Low

828818

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

854239

DGKE
Diacylglycerol kinase epsilon

1

0

High-throughput

0.279

Low

856186

SPSY
Spermine synthase

1

0

High-throughput

0.279

Low

891466

CTXN1
Cortexin-1

1

0

High-throughput

0.279

Low

964116

CD83
CD83 antigen

1

0

High-throughput

0.279

Low

990146

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.279

Low

1030098

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.279

Low

1030991

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1032983

PLD1
Phospholipase D1

1

0

High-throughput

0.279

Low

1057521

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.279

Low

1062365

CND2
Condensin complex subunit 2

1

0

High-throughput

0.279

Low

1086896

THTR
Thiosulfate sulfurtransferase

1

0

High-throughput

0.279

Low

1102457

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.279

Low

1121062

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.279

Low

1156174

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

1156253

TYW1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B

1

0

High-throughput

0.279

Low

1162223

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

0

High-throughput

0.279

Low

1166500

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1184451

CENPQ
Centromere protein Q

1

0

High-throughput

0.279

Low

1187572

TRM1L
TRMT1-like protein

1

0

High-throughput

0.279

Low

1190015

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.279

Low

1190249

LRP10
Low-density lipoprotein receptor-related protein 10

1

0

High-throughput

0.279

Low

1190539

TMED4
Transmembrane emp24 domain-containing protein 4

1

0

High-throughput

0.279

Low

1190540

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

0

High-throughput

0.279

Low

1190542

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1190543

TM192
Transmembrane protein 192

1

0

High-throughput

0.279

Low

1190544

ASTRC
Protein Aster-C

1

0

High-throughput

0.279

Low

1190545

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

1

0

High-throughput

0.279

Low

1190548

KDM1B
Lysine-specific histone demethylase 2

1

0

High-throughput

0.279

Low

1190549

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.279

Low

1190551

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1190552

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

1190556

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

0

High-throughput

0.279

Low

1190558

DNJC1
DnaJ homolog subfamily C member 1

1

0

High-throughput

0.279

Low

1190559

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

1190560

SEC62
Translocation protein SEC62

1

0

High-throughput

0.279

Low

1190561

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

High-throughput

0.279

Low

1190562

SEM4C
Semaphorin-4C

1

0

High-throughput

0.279

Low

1190564

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1190565

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1190570

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

0

High-throughput

0.279

Low

1190572

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1190573

RBM28
RNA-binding protein 28

1

0

High-throughput

0.279

Low

1190575

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1190576

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

High-throughput

0.279

Low

1190578

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.279

Low

1190579

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.279

Low

1190580

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

1190581

FEM1B
Protein fem-1 homolog B

1

0

High-throughput

0.279

Low

1190582

ZN346
Zinc finger protein 346

1

0

High-throughput

0.279

Low

1190584

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.279

Low

1190585

EXOG
Nuclease EXOG, mitochondrial

1

0

High-throughput

0.279

Low

1190587

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.279

Low

779662

CCNF
Cyclin-F

1

0

High-throughput

0.269

Low

1069721

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.269

Low

227903

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

294978

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

299404

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.249

Low

347177

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

553059

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

573766

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

651562

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

720800

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1087556

CAH9
Carbonic anhydrase 9

1

0

Small-scale

0.249

Low

1165712

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1170592

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1184184

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

1190563

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

High-throughput

0.249

Low

1190567

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1190574

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1190577

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1190586

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.249

Low

1190588

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.249

Low

1190571

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

402200

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

831459

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.213

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024