Protein: INT4
Integrator complex subunit 4 (Int4)

Gene: INT4, INTS4
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q96HW7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005768 - endosome
GO:0010496 - intercellular transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

930960

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

3

1

High-throughput

0.871

High

672241

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

3

0

High-throughput

0.827

High

1293889

INT9
Integrator complex subunit 9

2

3

Small-scale

0.811

High

1135522

INT11
Integrator complex subunit 11

2

3

Small-scale

0.776

High

1293888

BMP2K
BMP-2-inducible protein kinase

2

0

High-throughput

0.770

High

915259

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.691

High

160141

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

3

0

High-throughput

0.648

High

205834

TGON2
Trans-Golgi network integral membrane protein 2

3

0

High-throughput

0.638

High

1293902

VSIG4
V-set and immunoglobulin domain-containing protein 4

3

1

High-throughput

0.609

High

124044

SPT5H
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

1293884

MEIS3
Homeobox protein Meis3

2

0

High-throughput

0.580

High

1293895

LHX3
LIM/homeobox protein Lhx3

2

0

High-throughput

0.580

High

906779

NCS1
Neuronal calcium sensor 1

1

0

High-throughput

0.578

High

321618

AP2A1
AP-2 complex subunit alpha-1

2

1

High-throughput

0.574

High

1204513

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

1

High-throughput

0.574

High

1237310

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.574

High

1253276

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

1

High-throughput

0.574

High

1293896

CLC2D
C-type lectin domain family 2 member D

2

2

High-throughput

0.574

High

1231107

INT1
Integrator complex subunit 1

2

0

High-throughput

0.559

High

1293891

INT10
Integrator complex subunit 10

2

0

Small-scale

0.559

High

1293898

INT6
Integrator complex subunit 6

2

0

Small-scale

0.559

High

1030750

SLAF1
Signaling lymphocytic activation molecule

2

1

High-throughput

0.558

High

1201270

Q86V94
LOC554223 protein

2

2

High-throughput

0.558

High

1244104

ZMIZ2
Zinc finger MIZ domain-containing protein 2

1

0

High-throughput

0.549

High

893590

SEM1
26S proteasome complex subunit SEM1

2

0

Small-scale

0.547

High

1236680

USBP1
Harmonin-binding protein USHBP1

1

1

High-throughput

0.523

High

149170

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.517

High

452468

PGFRB
Platelet-derived growth factor receptor beta

1

0

High-throughput

0.513

High

454743

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

583767

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

676968

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

0

High-throughput

0.513

High

864971

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

897600

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

957912

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

996828

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1293883

INT14
Integrator complex subunit 14

1

0

High-throughput

0.513

High

1293886

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.513

High

354537

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

1

High-throughput

0.504

High

177604

SIGL5
Sialic acid-binding Ig-like lectin 5

1

1

High-throughput

0.489

High

253953

ADA11
Disintegrin and metalloproteinase domain-containing protein 11

1

1

High-throughput

0.489

High

302194

AP2A2
AP-2 complex subunit alpha-2

1

1

High-throughput

0.489

High

355052

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.489

High

488341

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.489

High

1020141

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

3

High-throughput

0.489

High

1259486

CLC4C
C-type lectin domain family 4 member C

1

2

High-throughput

0.489

High

1293899

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.489

High

487677

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

980839

TLE3
Transducin-like enhancer protein 3

1

1

High-throughput

0.479

High

1246143

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.479

High

1269357

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1068861

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.460

High

326747

SNAI1
Zinc finger protein SNAI1

1

0

High-throughput

0.458

High

726986

FUS
RNA-binding protein FUS

1

0

High-throughput

0.458

High

917744

H4
Histone H4

1

0

High-throughput

0.458

High

1052004

ELOA1
Elongin-A

1

0

Small-scale

0.458

High

1055450

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.458

High

1080234

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1148320

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1160527

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

1221345

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.458

High

1288237

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1293890

INT13
Integrator complex subunit 13

1

0

Small-scale

0.458

High

1293892

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1203565

STING
Stimulator of interferon genes protein

1

0

Small-scale

0.426

High

1287136

FAF2
FAS-associated factor 2

3

0

High-throughput

0.347

High

702279

CD70
CD70 antigen

2

0

High-throughput

0.328

High

771228

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.328

High

778594

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.328

High

1067937

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.328

High

1293887

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

506259

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.282

High

68087

HIDE1
Protein HIDE1

1

0

High-throughput

0.279

Low

131942

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

217348

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.279

Low

353083

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.279

Low

595560

GRAH
Granzyme H

1

0

High-throughput

0.279

Low

686359

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.279

Low

726050

ADDB
Beta-adducin

1

0

High-throughput

0.279

Low

795380

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

1083591

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

1121321

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.279

Low

1166531

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.279

Low

1198011

CLC14
C-type lectin domain family 14 member A

1

0

High-throughput

0.279

Low

1202529

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1232057

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1254630

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1293885

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.279

Low

1293893

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1293897

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

1293900

PCDAC
Protocadherin alpha-12

1

0

High-throughput

0.279

Low

1293901

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.279

Low

1293903

PCDB3
Protocadherin beta-3

1

0

High-throughput

0.279

Low

146381

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.249

Low

385346

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

1171240

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1173040

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

1293894

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024