Protein: TGS1
Trimethylguanosine synthase (EC 2.1.1.-) (CLL-associated antigen KW-2) (Cap-specific guanine-N2 methyltransferase) (Hepatocellular carcinoma-associated antigen 137) (Nuclear receptor coactivator 6-interacting protein) (PRIP-interacting protein with methyltransferase motif) (PIMT) (PIPMT)

Gene: TGS1
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q96RS0

Gene Ontology (top 5):
GO:0000387 - spliceosomal snRNP assembly
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

603659

FBRL
rRNA 2'-O-methyltransferase fibrillarin

5

0

Small-scale

0.688

High

911938

RUXF
Small nuclear ribonucleoprotein F

3

1

High-throughput

0.675

High

453892

RU2A
U2 small nuclear ribonucleoprotein A'

3

1

High-throughput

0.667

High

1057786

NCOA6
Nuclear receptor coactivator 6

3

0

Small-scale

0.650

High

1301362

NOP58
Nucleolar protein 58

2

1

Small-scale

0.639

High

539115

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.628

High

928002

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

2

High-throughput

0.628

High

998997

EP300
Histone acetyltransferase p300

2

1

Small-scale

0.624

High

1301352

TGS1
Trimethylguanosine synthase

1

1

Small-scale

0.621

High

912097

RUXG
Small nuclear ribonucleoprotein G

2

4

High-throughput

0.611

High

1116474

LARP7
La-related protein 7

2

1

High-throughput

0.611

High

442413

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

0

High-throughput

0.602

High

448786

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.602

High

911723

RUXE
Small nuclear ribonucleoprotein E

2

0

High-throughput

0.602

High

163170

XPO1
Exportin-1

2

1

Small-scale

0.595

High

735095

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.580

High

1199961

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.580

High

750431

COIL
Coilin

2

0

High-throughput

0.575

High

1270768

CBP
CREB-binding protein

1

1

Small-scale

0.561

High

1076190

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

Small-scale

0.537

High

403317

LA
Lupus La protein

1

1

High-throughput

0.536

High

441353

RU2B
U2 small nuclear ribonucleoprotein B''

1

1

High-throughput

0.536

High

446755

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

522634

MYH7
Myosin-7

1

1

High-throughput

0.536

High

912710

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.536

High

1063174

SEPT2
Septin-2

1

3

High-throughput

0.536

High

1076387

IKBB
NF-kappa-B inhibitor beta

1

1

High-throughput

0.536

High

1080973

SEPT7
Septin-7

1

3

High-throughput

0.536

High

1281668

LSM10
U7 snRNA-associated Sm-like protein LSm10

1

2

High-throughput

0.536

High

1301364

MYH4
Myosin-4

1

1

High-throughput

0.536

High

167003

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

0

High-throughput

0.518

High

529601

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

200229

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

0

High-throughput

0.513

High

215375

U3IP2
U3 small nucleolar RNA-interacting protein 2

1

0

High-throughput

0.513

High

572524

IBP3
Insulin-like growth factor-binding protein 3

1

0

High-throughput

0.513

High

659938

ERCC5
DNA excision repair protein ERCC-5

1

0

High-throughput

0.513

High

742482

SYUA
Alpha-synuclein

1

0

High-throughput

0.513

High

853687

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.513

High

912544

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

949209

LSM11
U7 snRNA-associated Sm-like protein LSm11

1

0

High-throughput

0.513

High

1050036

SCRIB
Protein scribble homolog

1

0

High-throughput

0.513

High

1082142

CRY1
Cryptochrome-1

1

0

High-throughput

0.513

High

1131600

ZMYM1
Zinc finger MYM-type protein 1

1

0

High-throughput

0.513

High

1193021

ZN467
Zinc finger protein 467

1

0

High-throughput

0.513

High

1222372

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

0

High-throughput

0.513

High

1297313

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

1301353

SRBS1
Sorbin and SH3 domain-containing protein 1

1

0

High-throughput

0.513

High

1301358

DNJB4
DnaJ homolog subfamily B member 4

1

0

High-throughput

0.513

High

1301360

MAGD2
Melanoma-associated antigen D2

1

0

High-throughput

0.513

High

1301361

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.513

High

268234

EED
Polycomb protein EED

1

0

Small-scale

0.504

High

1039437

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

0

High-throughput

0.493

High

782639

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

Small-scale

0.480

High

1294803

RSRC1
Serine/Arginine-related protein 53

1

1

High-throughput

0.479

High

1171334

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1301354

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1301355

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.458

High

1301356

DCA13
DDB1- and CUL4-associated factor 13

1

0

Small-scale

0.458

High

1301359

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

68449

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

4

High-throughput

0.445

High

110878

H7C5Q0
Arginine and serine rich coiled-coil 1

1

1

High-throughput

0.445

High

1075730

SF01
Splicing factor 1

1

0

High-throughput

0.438

High

1218920

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

1301357

SEP10
Septin-10

1

3

High-throughput

0.437

High

91557

E7EW69
Septin

1

3

High-throughput

0.407

High

1230101

F177A
Protein FAM177A1

3

0

High-throughput

0.347

High

195743

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

661403

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1027876

MYBPH
Myosin-binding protein H

1

0

High-throughput

0.279

Low

1223498

TEFF1
Tomoregulin-1

1

0

High-throughput

0.279

Low

1301363

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024