Protein: SRPK3
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)

Gene: SRPK3
Organism: Homo sapiens
Interactions: 190
UniProt ID: Q9UPE1

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1037914

PRP4K
Serine/threonine-protein kinase PRP4 homolog

3

20

High-throughput

0.871

High

1302101

SRPK1
SRSF protein kinase 1

2

18

High-throughput

0.855

High

442596

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

20

High-throughput

0.811

High

446842

SNRPA
U1 small nuclear ribonucleoprotein A

2

20

High-throughput

0.811

High

1058069

RRP5
Protein RRP5 homolog

2

11

High-throughput

0.811

High

789582

RBM34
RNA-binding protein 34

2

20

High-throughput

0.726

High

1054671

RBM39
RNA-binding protein 39

2

20

High-throughput

0.726

High

1347054

RBM28
RNA-binding protein 28

2

20

High-throughput

0.726

High

165594

SR140
U2 snRNP-associated SURP motif-containing protein

1

19

High-throughput

0.691

High

202321

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

15

High-throughput

0.691

High

304673

SCAF4
SR-related and CTD-associated factor 4

1

6

High-throughput

0.691

High

582563

NUCL
Nucleolin

1

18

High-throughput

0.691

High

641982

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

High-throughput

0.691

High

745345

RBMX
RNA-binding motif protein, X chromosome

1

20

High-throughput

0.691

High

833992

CLK2
Dual specificity protein kinase CLK2

1

17

High-throughput

0.691

High

836092

GSK3B
Glycogen synthase kinase-3 beta

1

20

High-throughput

0.691

High

841354

CDK7
Cyclin-dependent kinase 7

1

19

High-throughput

0.691

High

853125

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

20

High-throughput

0.691

High

883311

PRD15
PR domain zinc finger protein 15

1

4

High-throughput

0.691

High

943022

SRPK2
SRSF protein kinase 2

1

18

High-throughput

0.691

High

952178

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.691

High

964081

SRSF2
Serine/arginine-rich splicing factor 2

1

20

High-throughput

0.691

High

984136

SRS11
Serine/arginine-rich splicing factor 11

1

16

High-throughput

0.691

High

992994

SRSF1
Serine/arginine-rich splicing factor 1

1

20

High-throughput

0.691

High

993871

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.691

High

1040444

TRA2A
Transformer-2 protein homolog alpha

1

20

High-throughput

0.691

High

1047648

CDK13
Cyclin-dependent kinase 13

1

19

High-throughput

0.691

High

1060650

ZN638
Zinc finger protein 638

1

15

High-throughput

0.691

High

1073653

SF3B4
Splicing factor 3B subunit 4

1

20

High-throughput

0.691

High

1198931

RBM23
Probable RNA-binding protein 23

1

20

High-throughput

0.691

High

1288224

MSI2H
RNA-binding protein Musashi homolog 2

1

20

High-throughput

0.691

High

1316936

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

20

High-throughput

0.691

High

1328441

GZF1
GDNF-inducible zinc finger protein 1

1

8

High-throughput

0.691

High

1356523

RALY
RNA-binding protein Raly

1

14

High-throughput

0.691

High

1332284

CCD86
Coiled-coil domain-containing protein 86

3

2

High-throughput

0.675

High

323312

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

19

High-throughput

0.628

High

448856

RU1C
U1 small nuclear ribonucleoprotein C

2

5

High-throughput

0.628

High

878382

NH2L1
NHP2-like protein 1

2

5

High-throughput

0.628

High

1040734

KRR1
KRR1 small subunit processome component homolog

2

2

High-throughput

0.628

High

1045735

NOG2
Nucleolar GTP-binding protein 2

2

5

High-throughput

0.628

High

1057726

RRP1B
Ribosomal RNA processing protein 1 homolog B

2

15

High-throughput

0.628

High

1162484

CC137
Coiled-coil domain-containing protein 137

2

1

High-throughput

0.628

High

1186279

PHF5A
PHD finger-like domain-containing protein 5A

2

3

High-throughput

0.628

High

1254847

DDX54
ATP-dependent RNA helicase DDX54

2

20

High-throughput

0.628

High

1326376

DDX24
ATP-dependent RNA helicase DDX24

2

20

High-throughput

0.628

High

963288

U2AF1
Splicing factor U2AF 35 kDa subunit

1

9

High-throughput

0.618

High

1028875

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.618

High

1029162

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.618

High

1294319

SPF45
Splicing factor 45

1

20

High-throughput

0.618

High

1355615

PUF60
Poly(U)-binding-splicing factor PUF60

1

20

High-throughput

0.618

High

432368

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

438626

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

864852

MK12
Mitogen-activated protein kinase 12

1

18

High-throughput

0.618

High

577707

SON
Protein SON

3

20

High-throughput

0.616

High

1222438

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

3

7

High-throughput

0.616

High

1306847

EBP2
Probable rRNA-processing protein EBP2

3

2

High-throughput

0.616

High

1357646

CHTOP
Chromatin target of PRMT1 protein

2

3

High-throughput

0.601

High

273310

SURF6
Surfeit locus protein 6

2

4

High-throughput

0.574

High

281469

RL1D1
Ribosomal L1 domain-containing protein 1

2

7

High-throughput

0.574

High

802268

NOP2
Probable 28S rRNA

2

3

High-throughput

0.574

High

1065909

RRS1
Ribosome biogenesis regulatory protein homolog

2

2

High-throughput

0.574

High

1073296

PUM3
Pumilio homolog 3

2

12

High-throughput

0.574

High

1255240

BRX1
Ribosome biogenesis protein BRX1 homolog

2

10

High-throughput

0.574

High

1259537

NOC3L
Nucleolar complex protein 3 homolog

2

5

High-throughput

0.574

High

1310617

LLPH
Protein LLP homolog

2

1

High-throughput

0.574

High

1332937

RPF2
Ribosome production factor 2 homolog

2

3

High-throughput

0.574

High

1343079

LUC7L
Putative RNA-binding protein Luc7-like 1

2

15

High-throughput

0.574

High

1357643

RRP15
RRP15-like protein

2

2

High-throughput

0.574

High

1263320

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

9

Small-scale

0.553

High

117862

MYO1C
Unconventional myosin-Ic

1

20

High-throughput

0.536

High

133731

NOP56
Nucleolar protein 56

1

3

High-throughput

0.536

High

172537

NKRF
NF-kappa-B-repressing factor

1

2

High-throughput

0.536

High

177560

NVL
Nuclear valosin-containing protein-like

1

6

High-throughput

0.536

High

195575

DHX15
ATP-dependent RNA helicase DHX15

1

10

High-throughput

0.536

High

214692

MYO1B
Unconventional myosin-Ib

1

18

High-throughput

0.536

High

242604

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

3

High-throughput

0.536

High

269938

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

19

High-throughput

0.536

High

300289

PRP6
Pre-mRNA-processing factor 6

1

13

High-throughput

0.536

High

308274

LC7L3
Luc7-like protein 3

1

16

High-throughput

0.536

High

331905

NSD2
Histone-lysine N-methyltransferase NSD2

1

5

High-throughput

0.536

High

376340

ANXA1
Annexin A1

1

5

High-throughput

0.536

High

509165

TOP2A
DNA topoisomerase 2-alpha

1

5

High-throughput

0.536

High

539188

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

8

High-throughput

0.536

High

560009

H12
Histone H1.2

1

13

High-throughput

0.536

High

563222

YBOX3
Y-box-binding protein 3

1

13

High-throughput

0.536

High

578195

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.536

High

608662

H1T
Histone H1t

1

13

High-throughput

0.536

High

642679

RL13
Large ribosomal subunit protein eL13

1

7

High-throughput

0.536

High

675067

KPYR
Pyruvate kinase PKLR

1

6

High-throughput

0.536

High

722059

RFC4
Replication factor C subunit 4

1

7

High-throughput

0.536

High

773631

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

853754

IMA5
Importin subunit alpha-5

1

9

High-throughput

0.536

High

865096

TTC3
E3 ubiquitin-protein ligase TTC3

1

13

High-throughput

0.536

High

875766

MFAP1
Microfibrillar-associated protein 1

1

3

High-throughput

0.536

High

880071

RRP1
Ribosomal RNA processing protein 1 homolog A

1

8

High-throughput

0.536

High

899408

RL15
Large ribosomal subunit protein eL15

1

3

High-throughput

0.536

High

900317

RL37A
Large ribosomal subunit protein eL43

1

1

High-throughput

0.536

High

911998

RUXF
Small nuclear ribonucleoprotein F

1

7

High-throughput

0.536

High

912399

SMD1
Small nuclear ribonucleoprotein Sm D1

1

9

High-throughput

0.536

High

913835

RL7A
Large ribosomal subunit protein eL8

1

5

High-throughput

0.536

High

960589

PURA
Transcriptional activator protein Pur-alpha

1

8

High-throughput

0.536

High

977338

CEBPZ
CCAAT/enhancer-binding protein zeta

1

3

High-throughput

0.536

High

994400

DHX9
ATP-dependent RNA helicase A

1

18

High-throughput

0.536

High

998222

NCBP1
Nuclear cap-binding protein subunit 1

1

5

High-throughput

0.536

High

1017101

TROP
Trophinin

1

7

High-throughput

0.536

High

1040853

PWP1
Periodic tryptophan protein 1 homolog

1

20

High-throughput

0.536

High

1058180

BMS1
Ribosome biogenesis protein BMS1 homolog

1

3

High-throughput

0.536

High

1071762

TTF1
Transcription termination factor 1

1

7

High-throughput

0.536

High

1121217

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

16

High-throughput

0.536

High

1135365

ATD3B
ATPase family AAA domain-containing protein 3B

1

12

High-throughput

0.536

High

1164158

WDR74
WD repeat-containing protein 74

1

20

High-throughput

0.536

High

1184093

DHX30
ATP-dependent RNA helicase DHX30

1

17

High-throughput

0.536

High

1187858

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

11

High-throughput

0.536

High

1202186

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

14

High-throughput

0.536

High

1222877

SRRM1
Serine/arginine repetitive matrix protein 1

1

20

High-throughput

0.536

High

1224549

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

16

High-throughput

0.536

High

1239291

PR38A
Pre-mRNA-splicing factor 38A

1

5

High-throughput

0.536

High

1260493

CATIN
Splicing factor Cactin

1

2

High-throughput

0.536

High

1284172

LRC59
Leucine-rich repeat-containing protein 59

1

15

High-throughput

0.536

High

1292686

DDX27
Probable ATP-dependent RNA helicase DDX27

1

20

High-throughput

0.536

High

1303861

CDC5L
Cell division cycle 5-like protein

1

20

High-throughput

0.536

High

1304770

SCAFB
Protein SCAF11

1

20

High-throughput

0.536

High

1309673

MBB1A
Myb-binding protein 1A

1

1

High-throughput

0.536

High

1314113

GNL3
Guanine nucleotide-binding protein-like 3

1

5

High-throughput

0.536

High

1315619

SRRT
Serrate RNA effector molecule homolog

1

4

High-throughput

0.536

High

1317936

GTPB4
GTP-binding protein 4

1

5

High-throughput

0.536

High

1326284

REXO4
RNA exonuclease 4

1

2

High-throughput

0.536

High

1327382

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.536

High

1327552

XRN2
5'-3' exoribonuclease 2

1

3

High-throughput

0.536

High

1328105

DDX47
Probable ATP-dependent RNA helicase DDX47

1

20

High-throughput

0.536

High

1333564

DDX31
ATP-dependent DNA helicase DDX31

1

20

High-throughput

0.536

High

1336009

MOV10
Helicase MOV-10

1

5

High-throughput

0.536

High

1343167

SSF1
Suppressor of SWI4 1 homolog

1

2

High-throughput

0.536

High

1343594

EXOS5
Exosome complex component RRP46

1

1

High-throughput

0.536

High

1344170

DDX21
Nucleolar RNA helicase 2

1

20

High-throughput

0.536

High

1345033

RNC
Ribonuclease 3

1

8

High-throughput

0.536

High

1346782

DDX18
ATP-dependent RNA helicase DDX18

1

20

High-throughput

0.536

High

1347797

LYAR
Cell growth-regulating nucleolar protein

1

4

High-throughput

0.536

High

1348280

DDX56
Probable ATP-dependent RNA helicase DDX56

1

20

High-throughput

0.536

High

1353892

TFP11
Tuftelin-interacting protein 11

1

1

High-throughput

0.536

High

1356399

MRT4
mRNA turnover protein 4 homolog

1

8

High-throughput

0.536

High

1356598

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

20

High-throughput

0.536

High

1357638

SRRM2
Serine/arginine repetitive matrix protein 2

1

20

High-throughput

0.536

High

1357642

EXOS1
Exosome complex component CSL4

1

1

High-throughput

0.536

High

1357645

NOC2L
Nucleolar complex protein 2 homolog

1

3

High-throughput

0.536

High

1357648

PAXB1
PAX3- and PAX7-binding protein 1

1

1

High-throughput

0.536

High

966503

EXOSX
Exosome complex component 10

1

0

High-throughput

0.513

High

1076240

ZNHI3
Zinc finger HIT domain-containing protein 3

1

0

High-throughput

0.513

High

1314749

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.513

High

1334772

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.513

High

1357644

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

127607

RPOM
DNA-directed RNA polymerase, mitochondrial

1

2

High-throughput

0.489

High

196232

RRP8
Ribosomal RNA-processing protein 8

1

2

High-throughput

0.489

High

315448

NSA2
Ribosome biogenesis protein NSA2 homolog

1

2

High-throughput

0.489

High

828943

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.489

High

1016346

TBL3
Transducin beta-like protein 3

1

20

High-throughput

0.489

High

1115602

GLYR1
Cytokine-like nuclear factor N-PAC

1

6

High-throughput

0.489

High

1121038

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

1

High-throughput

0.489

High

1150384

RL7L
Ribosomal protein uL30-like

1

3

High-throughput

0.489

High

1238734

KRI1
Protein KRI1 homolog

1

4

High-throughput

0.489

High

1246503

WDR36
WD repeat-containing protein 36

1

14

High-throughput

0.489

High

1268823

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.489

High

1297929

RIPR3
RIPOR family member 3

1

1

High-throughput

0.489

High

1310066

CG050
Uncharacterized protein C7orf50

1

2

High-throughput

0.489

High

1315972

MAK16
Protein MAK16 homolog

1

1

High-throughput

0.489

High

1334504

RPF1
Ribosome production factor 1

1

3

High-throughput

0.489

High

1342712

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

1

High-throughput

0.489

High

1346014

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

19

High-throughput

0.489

High

1346969

NLE1
Notchless protein homolog 1

1

17

High-throughput

0.489

High

1348127

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

2

High-throughput

0.489

High

1349307

NOP53
Ribosome biogenesis protein NOP53

1

2

High-throughput

0.489

High

1355307

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.489

High

1357573

DIM1
Probable dimethyladenosine transferase

1

2

High-throughput

0.489

High

1357639

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

2

High-throughput

0.489

High

1357641

LC7L2
Putative RNA-binding protein Luc7-like 2

1

17

High-throughput

0.489

High

1357647

LAS1L
Ribosomal biogenesis protein LAS1L

1

2

High-throughput

0.489

High

1357649

RT18B
Small ribosomal subunit protein mS40

1

2

High-throughput

0.489

High

684395

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

760390

RL3
Large ribosomal subunit protein uL3

1

4

High-throughput

0.479

High

898795

RL26
Large ribosomal subunit protein uL24

1

3

High-throughput

0.479

High

910158

1433E
14-3-3 protein epsilon

1

15

High-throughput

0.479

High

1072065

PCBP1
Poly(rC)-binding protein 1

1

20

High-throughput

0.479

High

1281976

RL36L
Ribosomal protein eL42-like

1

3

High-throughput

0.479

High

1357640

TR150
Thyroid hormone receptor-associated protein 3

1

20

High-throughput

0.479

High

882641

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.445

High

1357590

RL26L
Ribosomal protein uL24-like

1

3

High-throughput

0.437

High

68469

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

12

High-throughput

0.407

High

230100

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.279

Low

1282223

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

1

0

High-throughput

0.279

Low

1336598

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024