Protein: PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)

Gene: PLOD1
Organism: Homo sapiens
Interactions: 195
UniProt ID: Q02809

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0005506 - iron ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008475 - procollagen-lysine 5-dioxygenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

129911

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

2

10

High-throughput

0.811

High

237047

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

2

10

Small-scale

0.799

High

972725

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

10

Small-scale

0.778

High

453301

ROA1
Heterogeneous nuclear ribonucleoprotein A1

3

3

High-throughput

0.667

High

441060

CO4A2

2

20

High-throughput

0.628

High

517941

CO6A1

2

20

High-throughput

0.628

High

517998

CO6A2

2

20

High-throughput

0.628

High

760524

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

2

20

High-throughput

0.628

High

972779

P3H3
Prolyl 3-hydroxylase 3

2

1

High-throughput

0.628

High

972797

SC65
Endoplasmic reticulum protein SC65

2

1

High-throughput

0.628

High

682777

HNRH1
Heterogeneous nuclear ribonucleoprotein H

3

6

High-throughput

0.616

High

877702

FOXA1
Hepatocyte nuclear factor 3-alpha

3

1

High-throughput

0.616

High

878642

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

3

6

High-throughput

0.613

High

358499

CO1A1
Collagen alpha-1(I) chain

3

20

Small-scale

0.604

High

972822

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

2

0

High-throughput

0.602

High

972825

FBX6
F-box only protein 6

3

6

High-throughput

0.599

High

346570

MYC
Myc proto-oncogene protein

3

4

High-throughput

0.585

High

128995

PLK4
Serine/threonine-protein kinase PLK4

2

1

High-throughput

0.574

High

231498

KIF1B
Kinesin-like protein KIF1B

2

4

High-throughput

0.574

High

358661

CO4A1

2

20

High-throughput

0.574

High

596157

CO5A1

2

20

High-throughput

0.574

High

666803

CO4A5

2

20

High-throughput

0.574

High

972726

COEA1
Collagen alpha-1(XIV) chain

2

20

High-throughput

0.574

High

972738

CO4A6

2

20

High-throughput

0.574

High

972758

PRC2B
Protein PRRC2B

2

1

High-throughput

0.574

High

972777

KI18B
Kinesin-like protein KIF18B

2

2

High-throughput

0.574

High

972780

CHERP
Calcium homeostasis endoplasmic reticulum protein

2

1

High-throughput

0.574

High

972815

ZN106
Zinc finger protein 106

2

1

High-throughput

0.574

High

972836

COLQ
Acetylcholinesterase collagenic tail peptide

2

20

High-throughput

0.574

High

972838

RBM7
RNA-binding protein 7

2

1

High-throughput

0.574

High

358604

CO2A1
Collagen alpha-1(II) chain

2

20

High-throughput

0.567

High

671788

PDIA3
Protein disulfide-isomerase A3

1

7

Small-scale

0.561

High

972810

COPA1
Collagen alpha-1(XXV) chain

2

20

High-throughput

0.558

High

924489

GRB2
Growth factor receptor-bound protein 2

2

0

High-throughput

0.547

High

653562

CALR
Calreticulin

1

7

High-throughput

0.536

High

654273

CALX
Calnexin

1

7

High-throughput

0.536

High

972732

BIRC2
Baculoviral IAP repeat-containing protein 2

1

1

High-throughput

0.536

High

972735

CUL3
Cullin-3

1

6

High-throughput

0.536

High

972736

CUL4B
Cullin-4B

1

6

High-throughput

0.536

High

972764

SCAR3
Scavenger receptor class A member 3

1

20

High-throughput

0.536

High

972769

ARHGI
Rho guanine nucleotide exchange factor 18

1

1

High-throughput

0.536

High

972774

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

972806

COCA1

1

19

High-throughput

0.536

High

972834

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

4

High-throughput

0.536

High

166368

KIF3B
Kinesin-like protein KIF3B

1

2

High-throughput

0.515

High

972768

WDFY4
WD repeat- and FYVE domain-containing protein 4

1

2

High-throughput

0.515

High

555421

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

411359

INSR
Insulin receptor

1

9

High-throughput

0.500

High

125875

CDC7
Cell division cycle 7-related protein kinase

1

1

High-throughput

0.489

High

270403

KS6A5
Ribosomal protein S6 kinase alpha-5

1

1

High-throughput

0.489

High

852022

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

3

High-throughput

0.489

High

862503

CO4A4

1

20

High-throughput

0.489

High

972727

COGA1

1

20

High-throughput

0.489

High

972733

CUL1
Cullin-1

1

6

High-throughput

0.489

High

972734

CUL2
Cullin-2

1

6

High-throughput

0.489

High

972739

CO9A3

1

20

High-throughput

0.489

High

972744

EPHA7
Ephrin type-A receptor 7

1

9

High-throughput

0.489

High

972761

CODA1
Collagen alpha-1(XIII) chain

1

20

High-throughput

0.489

High

972776

CONA1

1

20

High-throughput

0.489

High

972785

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.489

High

972788

DCLK2
Serine/threonine-protein kinase DCLK2

1

1

High-throughput

0.489

High

972799

CUL5
Cullin-5

1

6

High-throughput

0.489

High

972805

COLA1

1

20

High-throughput

0.489

High

972809

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

20

High-throughput

0.489

High

972835

TAOK2
Serine/threonine-protein kinase TAO2

1

2

High-throughput

0.489

High

216215

CALU
Calumenin

1

3

High-throughput

0.479

High

227217

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

322501

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

338304

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.479

High

501994

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

503931

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

531801

PDIA4
Protein disulfide-isomerase A4

1

7

High-throughput

0.479

High

648729

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.479

High

718771

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

821844

HSP13
Heat shock 70 kDa protein 13

1

4

High-throughput

0.479

High

890108

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

900395

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

950935

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.479

High

972731

DNJC3
DnaJ homolog subfamily C member 3

1

13

High-throughput

0.479

High

972741

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.479

High

972752

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

3

High-throughput

0.479

High

972766

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

972781

DJC10
DnaJ homolog subfamily C member 10

1

14

High-throughput

0.479

High

972787

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.479

High

972789

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

972790

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.479

High

972800

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.479

High

972803

CALR3
Calreticulin-3

1

7

High-throughput

0.479

High

972813

DJC25
DnaJ homolog subfamily C member 25

1

10

High-throughput

0.479

High

972816

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

972828

DJB12
DnaJ homolog subfamily B member 12

1

9

High-throughput

0.479

High

972830

VAPA
Vesicle-associated membrane protein-associated protein A

1

3

High-throughput

0.479

High

972831

DJB11
DnaJ homolog subfamily B member 11

1

3

High-throughput

0.479

High

637240

CATS
Cathepsin S

1

3

High-throughput

0.470

High

125391

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

390836

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

972729

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.458

High

972747

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.458

High

435616

IGF1R
Insulin-like growth factor 1 receptor

1

9

High-throughput

0.457

High

891096

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

6

High-throughput

0.445

High

972760

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

972812

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.445

High

148700

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

205289

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.437

High

233381

NUPR1
Nuclear protein 1

1

2

High-throughput

0.437

High

272541

OFD1
Centriole and centriolar satellite protein OFD1

1

2

High-throughput

0.437

High

294731

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.437

High

312579

ARI2
E3 ubiquitin-protein ligase ARIH2

1

4

High-throughput

0.437

High

374084

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

379308

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.437

High

384677

NTRK1
High affinity nerve growth factor receptor

1

5

High-throughput

0.437

High

397919

ISG15
Ubiquitin-like protein ISG15

1

1

High-throughput

0.437

High

442084

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

1

High-throughput

0.437

High

552535

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

595998

EFNA1
Ephrin-A1

1

6

High-throughput

0.437

High

610360

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.437

High

651001

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

720270

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

856313

EFNA3
Ephrin-A3

1

6

High-throughput

0.437

High

869614

TERF1
Telomeric repeat-binding factor 1

1

3

High-throughput

0.437

High

901131

RND3
Rho-related GTP-binding protein RhoE

1

5

High-throughput

0.437

High

908402

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

972740

GRB7
Growth factor receptor-bound protein 7

1

1

Small-scale

0.437

High

972742

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.437

High

972743

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

972745

TERF2
Telomeric repeat-binding factor 2

1

3

High-throughput

0.437

High

972748

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

972749

E2F4
Transcription factor E2F4

1

1

High-throughput

0.437

High

972753

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

4

High-throughput

0.437

High

972754

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

972755

TECT1
Tectonic-1

1

5

High-throughput

0.437

High

972759

EPHAA
Ephrin type-A receptor 10

1

9

High-throughput

0.437

High

972762

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

972763

FTM
Protein fantom

1

3

High-throughput

0.437

High

972765

TECT3
Tectonic-3

1

5

High-throughput

0.437

High

972767

SYNE3
Nesprin-3

1

3

High-throughput

0.437

High

972770

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

972793

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

972796

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

3

High-throughput

0.437

High

972804

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

12

High-throughput

0.437

High

972807

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

1

High-throughput

0.437

High

972818

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

972820

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

972823

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.437

High

972824

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

3

High-throughput

0.437

High

972827

T106B
Transmembrane protein 106B

1

4

High-throughput

0.437

High

972833

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

68474

A8MWQ5
Collagen type XXV alpha 1 chain

1

20

High-throughput

0.407

High

306121

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

6

High-throughput

0.407

High

717724

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.407

High

853863

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.407

High

972811

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.407

High

972817

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

6

High-throughput

0.407

High

165452

SR140
U2 snRNP-associated SURP motif-containing protein

2

0

High-throughput

0.328

High

259352

DUS11
RNA/RNP complex-1-interacting phosphatase

2

0

High-throughput

0.328

High

317953

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

2

0

High-throughput

0.328

High

972757

ODFP2
Outer dense fiber protein 2

2

0

High-throughput

0.328

High

972771

KDM3B
Lysine-specific demethylase 3B

2

0

High-throughput

0.328

High

972772

PBIR2
PABIR family member 2

2

0

High-throughput

0.328

High

972775

MEX3D
RNA-binding protein MEX3D

2

0

High-throughput

0.328

High

972782

CI040
Uncharacterized protein C9orf40

2

0

High-throughput

0.328

High

972826

LATS2
Serine/threonine-protein kinase LATS2

2

0

High-throughput

0.318

High

972746

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.279

Low

972750

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.279

Low

972794

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

972798

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.279

Low

972801

SGK3
Serine/threonine-protein kinase Sgk3

1

0

High-throughput

0.279

Low

972802

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.279

Low

972808

ZBED2
Zinc finger BED domain-containing protein 2

1

0

High-throughput

0.279

Low

972814

GAN
Gigaxonin

1

0

High-throughput

0.279

Low

972783

LRC47
Leucine-rich repeat-containing protein 47

1

0

High-throughput

0.269

Low

972730

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

Small-scale

0.251

Low

182710

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

255698

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

304951

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.249

Low

807693

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.249

Low

823906

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

940800

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

972737

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

972751

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

972756

LARP7
La-related protein 7

1

0

High-throughput

0.249

Low

972773

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

972778

SL9A9
Sodium/hydrogen exchanger 9

1

0

Small-scale

0.249

Low

972784

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

972786

NIN
Ninein

1

0

High-throughput

0.249

Low

972791

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

972795

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.249

Low

972819

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

972821

MYO10
Unconventional myosin-X

1

0

Small-scale

0.249

Low

972829

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

972832

ZO2
Tight junction protein ZO-2

1

0

High-throughput

0.249

Low

972837

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

972728

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.232

Low

972792

RN169
E3 ubiquitin-protein ligase RNF169

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024