Protein: LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial (EC 3.4.-.-)

Gene: LACTB
Organism: Homo sapiens
Interactions: 161
UniProt ID: P83111

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006508 - proteolysis
GO:0006629 - lipid metabolic process
GO:0008233 - peptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

949097

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

1

High-throughput

0.618

High

325131

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

0

High-throughput

0.613

High

525481

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

3

0

High-throughput

0.613

High

519772

KCRU
Creatine kinase U-type, mitochondrial

2

1

High-throughput

0.611

High

475621

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

1

High-throughput

0.602

High

949175

COPRS
Coordinator of PRMT5 and differentiation stimulator

2

0

High-throughput

0.602

High

949140

ESR2
Estrogen receptor beta

2

1

High-throughput

0.571

High

274526

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

2

0

High-throughput

0.559

High

949171

SFXN1
Sideroflexin-1

2

0

High-throughput

0.559

High

949176

ANLN
Anillin

2

0

High-throughput

0.559

High

386519

P53
Cellular tumor antigen p53

1

0

Small-scale

0.537

High

568147

KCRS
Creatine kinase S-type, mitochondrial

1

1

High-throughput

0.536

High

949137

KCTD6
BTB/POZ domain-containing protein KCTD6

1

1

High-throughput

0.536

High

949160

NPS3B
Protein NipSnap homolog 3B

1

1

High-throughput

0.536

High

949187

NPS3A
Protein NipSnap homolog 3A

1

1

High-throughput

0.536

High

364862

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

543014

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

596043

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.513

High

670927

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

0

High-throughput

0.513

High

687132

CDD
Cytidine deaminase

1

0

High-throughput

0.513

High

717695

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.513

High

808020

GNPI1
Glucosamine-6-phosphate isomerase 1

1

0

High-throughput

0.513

High

900028

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.513

High

949109

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.513

High

949111

TSN
Translin

1

0

High-throughput

0.513

High

949112

HSPB2
Heat shock protein beta-2

1

0

High-throughput

0.513

High

949132

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

949158

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.513

High

949189

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

0

High-throughput

0.513

High

174802

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

949114

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.493

High

362379

CRP

1

1

High-throughput

0.489

High

815183

NPTX2
Neuronal pentraxin-2

1

1

High-throughput

0.489

High

949135

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

High-throughput

0.489

High

949184

IBTK
Inhibitor of Bruton tyrosine kinase

1

1

High-throughput

0.489

High

125366

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

1

High-throughput

0.479

High

209887

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

224614

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

1

High-throughput

0.479

High

297051

TOM70
Mitochondrial import receptor subunit TOM70

1

1

High-throughput

0.479

High

319793

HERC2
E3 ubiquitin-protein ligase HERC2

1

2

High-throughput

0.479

High

718750

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

737309

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.479

High

935729

UBX2A
UBX domain-containing protein 2A

1

2

High-throughput

0.479

High

949100

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

949107

UBX2B
UBX domain-containing protein 2B

1

2

High-throughput

0.479

High

949118

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.479

High

949120

MARC1
Mitochondrial amidoxime-reducing component 1

1

1

High-throughput

0.479

High

949121

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

1

1

High-throughput

0.479

High

949124

MIC27
MICOS complex subunit MIC27

1

1

High-throughput

0.479

High

949133

MICU2
Calcium uptake protein 2, mitochondrial

1

2

High-throughput

0.479

High

949142

MARC2
Mitochondrial amidoxime reducing component 2

1

1

High-throughput

0.479

High

949144

COA7
Cytochrome c oxidase assembly factor 7

1

1

High-throughput

0.479

High

949151

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.479

High

949154

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.479

High

949156

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

949157

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.479

High

949162

MIC26
MICOS complex subunit MIC26

1

1

High-throughput

0.479

High

949165

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.479

High

949166

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

1

Small-scale

0.479

High

949167

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.479

High

949181

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.479

High

949188

NSF1C
NSFL1 cofactor p47

1

2

High-throughput

0.479

High

949192

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.479

High

68555

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

0

High-throughput

0.458

High

118270

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

121293

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

0

High-throughput

0.458

High

135600

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

148677

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

203913

HTRA2
Serine protease HTRA2, mitochondrial

1

0

High-throughput

0.458

High

231087

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

264556

MTX2
Metaxin-2

1

0

High-throughput

0.458

High

276817

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.458

High

307350

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.458

High

322478

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

374048

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

495695

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.458

High

556613

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.458

High

568973

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.458

High

687191

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

High-throughput

0.458

High

736172

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

1

0

High-throughput

0.458

High

777541

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

817919

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

827911

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

0

High-throughput

0.458

High

851923

NDUA8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

1

0

High-throughput

0.458

High

864212

CCHL
Holocytochrome c-type synthase

1

0

High-throughput

0.458

High

873026

KAD2
Adenylate kinase 2, mitochondrial

1

0

High-throughput

0.458

High

916515

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

949098

CYC
Cytochrome c

1

0

High-throughput

0.458

High

949101

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

949102

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.458

High

949106

NUCG
Endonuclease G, mitochondrial

1

0

High-throughput

0.458

High

949108

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

949110

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

949113

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

949115

MIX23
Protein MIX23

1

0

High-throughput

0.458

High

949116

PREP
Presequence protease, mitochondrial

1

0

High-throughput

0.458

High

949119

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

0

High-throughput

0.458

High

949127

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

1

0

High-throughput

0.458

High

949129

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

949130

DCXR
L-xylulose reductase

1

0

High-throughput

0.458

High

949134

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.458

High

949136

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

949138

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

949141

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

949145

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

949146

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

949148

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

949150

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

949155

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

0

High-throughput

0.458

High

949163

B2L13
Bcl-2-like protein 13

1

0

High-throughput

0.458

High

949164

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.458

High

949168

PARL
Presenilin-associated rhomboid-like protein, mitochondrial

1

0

High-throughput

0.458

High

949169

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

949170

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

949174

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.458

High

949177

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

949178

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

949179

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

949180

DJC11
DnaJ homolog subfamily C member 11

1

0

High-throughput

0.458

High

949183

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

949186

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.458

High

949190

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.458

High

949191

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.458

High

369393

ESR1
Estrogen receptor

1

1

High-throughput

0.445

High

949122

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.445

High

949126

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.439

High

308611

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

949131

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.426

High

949152

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.426

High

949153

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

949143

C102A
Coiled-coil domain-containing protein 102A

2

0

High-throughput

0.324

High

175962

FOXN1
Forkhead box protein N1

1

0

High-throughput

0.279

Low

514367

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

949172

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

High-throughput

0.279

Low

949185

ZNFX1
NFX1-type zinc finger-containing protein 1

1

0

High-throughput

0.279

Low

949193

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

445843

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

0

High-throughput

0.269

Low

949128

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

0

High-throughput

0.269

Low

949139

MY18A
Unconventional myosin-XVIIIa

1

0

High-throughput

0.269

Low

949159

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.269

Low

489950

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

Small-scale

0.251

Low

100678

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

294708

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

330314

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.249

Low

346515

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

352580

TNFA
Tumor necrosis factor

1

0

High-throughput

0.249

Low

594892

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

949099

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

949104

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low

949117

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

0

High-throughput

0.249

Low

949123

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

0

High-throughput

0.249

Low

949125

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

949147

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

949161

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.249

Low

949173

DNJC4
DnaJ homolog subfamily C member 4

1

0

High-throughput

0.249

Low

949182

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

239936

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

949103

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

949105

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.232

Low

949149

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024