Protein: MBK2
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 (EC 2.7.12.1) (Dual specificity Yak1-related kinase mbk-2) (Minibrain Kinase 2)

Gene: MBK2, mbk-2
Organism: Caenorhabditis elegans
Interactions: 126
UniProt ID: Q9XTF3

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000793 - condensed chromosome
GO:0001556 - oocyte maturation
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

137341

CDC37
Probable Hsp90 co-chaperone cdc37

2

6

High-throughput

0.743

High

659251

CSK2B
Casein kinase II subunit beta

2

1

High-throughput

0.743

High

1093771

EGG3
Protein tyrosine phosphatase-like protein egg-3

4

9

Small-scale

0.701

High

136814

EGG4
Inactive protein-tyrosine phosphatase egg-4

3

5

Small-scale

0.677

High

105026

MOE1
CCCH-type zinc finger protein oma-1

3

6

Small-scale

0.655

High

1353304

Q9TXM1
Uncharacterized protein

3

2

Small-scale

0.646

High

105652

G5ED17
Protein kinase domain-containing protein

1

6

High-throughput

0.618

High

106148

G5EDL3
Aurora kinase

1

16

High-throughput

0.618

High

1325777

Q9GUP2
HECT-type E3 ubiquitin transferase

1

13

High-throughput

0.618

High

1353615

GSK3
Glycogen synthase kinase-3

1

19

High-throughput

0.618

High

713380

KTNA1
Meiotic spindle formation protein mei-1

2

13

Small-scale

0.602

High

711822

KLE2
Condensin-2 complex subunit kle-2

2

1

High-throughput

0.576

High

879091

SUMO
Small ubiquitin-related modifier

2

7

High-throughput

0.576

High

247766

EGG5
Inactive protein-tyrosine phosphatase egg-5

1

4

Small-scale

0.515

High

1094087

MEGG1
Protein meg-1

1

1

Small-scale

0.501

High

1095316

MOE2
CCCH-type zinc finger protein oma-2

1

4

Small-scale

0.501

High

1376847

MEX5
Zinc finger protein mex-5

1

4

Small-scale

0.501

High

80833

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

10

High-throughput

0.479

High

94018

F1LIM5
ZZ-type domain-containing protein

1

4

High-throughput

0.479

High

104631

LE418
Protein let-418

1

3

High-throughput

0.479

High

105079

CHS1
Chitin synthase chs-1

1

1

High-throughput

0.479

High

106307

LIN35
Retinoblastoma-like protein homolog lin-35

1

15

High-throughput

0.479

High

106317

G5EDT9
E3 ubiquitin-protein ligase UBR5

1

17

High-throughput

0.479

High

106898

G5EEK5
Very Early Transcript

1

2

High-throughput

0.479

High

107246

G5EF11
E2F/DP family winged-helix DNA-binding domain-containing protein

1

11

High-throughput

0.479

High

108160

EGL18
Putative transcription factor egl-18

1

5

High-throughput

0.479

High

110951

H9G2X3
Serine/threonine protein phosphatase 2A regulatory subunit

1

2

High-throughput

0.479

High

136351

TMOD
Tropomodulin

1

4

High-throughput

0.479

High

136554

O01585
Rho-GAP domain-containing protein

1

8

High-throughput

0.479

High

184377

GLD2
Poly(A) RNA polymerase gld-2

1

3

High-throughput

0.479

High

185301

6PGL
Putative 6-phosphogluconolactonase

1

2

High-throughput

0.479

High

219871

O45080
One cut domain family member

1

15

High-throughput

0.479

High

246633

O61201
GATOR complex protein MIO zinc-ribbon like domain-containing protein

1

16

High-throughput

0.479

High

247758

O61770
CABIT domain-containing protein

1

1

High-throughput

0.479

High

247864

ERGO1
Piwi-like protein ergo-1

1

2

High-throughput

0.479

High

675352

LIN9
Protein lin-9

1

2

High-throughput

0.479

High

697549

CLAS2
Protein CLASP-2

1

3

High-throughput

0.479

High

711978

RFC5
Probable replication factor C subunit 5

1

2

High-throughput

0.479

High

804400

TCPZ
T-complex protein 1 subunit zeta

1

13

High-throughput

0.479

High

858454

RFC4
Replication factor C subunit 4

1

1

High-throughput

0.479

High

998482

UBE4
Ubiquitin conjugation factor E4 ufd-2

1

6

High-throughput

0.479

High

999461

GUAA
Probable GMP synthase [glutamine-hydrolyzing]

1

5

High-throughput

0.479

High

1000139

LIN23
F-box/WD repeat-containing protein lin-23

1

16

High-throughput

0.479

High

1014721

LIN13
Zinc finger protein lin-13

1

2

High-throughput

0.479

High

1088761

CNOT7
CCR4-NOT transcription complex subunit 7

1

4

High-throughput

0.479

High

1089120

Q17746
ZZ-type domain-containing protein

1

4

High-throughput

0.479

High

1090246

IPYR
Inorganic pyrophosphatase 1

1

1

High-throughput

0.479

High

1090871

ZW10
Centromere/kinetochore protein zw10 homolog

1

1

High-throughput

0.479

High

1090893

HM38
Homeobox protein ceh-38

1

10

High-throughput

0.479

High

1093942

ATAD3
ATPase family AAA domain-containing protein 3

1

14

High-throughput

0.479

High

1094008

CNOT1
CCR4-NOT transcription complex subunit let-711

1

17

High-throughput

0.479

High

1094090

MEGG2
Protein meg-2

1

1

High-throughput

0.479

High

1094269

Q21501
YEATS domain-containing protein 4

1

6

High-throughput

0.479

High

1094763

Q22240
Ubiquitin carboxyl-terminal hydrolase 47

1

12

High-throughput

0.479

High

1094994

TFDP1
Transcription factor dpl-1

1

8

High-throughput

0.479

High

1095273

MRE11
Double-strand break repair protein mre-11

1

2

High-throughput

0.479

High

1099774

LI15B
Protein lin-15B

1

4

High-throughput

0.479

High

1122571

Q565A8
SUZ domain-containing protein

1

1

High-throughput

0.479

High

1176569

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.479

High

1212085

CASP
Protein CASP

1

19

High-throughput

0.479

High

1228708

Q8MPS6
Exportin-1 C-terminal domain-containing protein

1

5

High-throughput

0.479

High

1274685

Q93413
Helicase ATP-binding domain-containing protein

1

15

High-throughput

0.479

High

1274799

Q93934
Adenosine kinase

1

1

High-throughput

0.479

High

1280170

GLD3
Defective in germ line development protein 3

1

2

High-throughput

0.479

High

1325942

RUVB2
RuvB-like 2

1

4

High-throughput

0.479

High

1341610

Q9N4A5
Phosphotransferase

1

3

High-throughput

0.479

High

1341664

Q9N533
GATOR complex protein WDR24

1

14

High-throughput

0.479

High

1341953

SSL1
Helicase ssl-1

1

5

High-throughput

0.479

High

1342096

Q9NGT3
HORMA domain-containing protein

1

1

High-throughput

0.479

High

1353637

Q9U3F2
DNA replication ATP-dependent helicase/nuclease

1

11

High-throughput

0.479

High

1341597

Q9N415
Variant SH3 domain protein

1

5

High-throughput

0.464

High

103973

G5EBG0
HORMA domain-containing protein

1

0

High-throughput

0.458

High

106562

G5EE09
poly(A)-specific ribonuclease

1

0

High-throughput

0.458

High

184414

O17151
LIn-8 Domain containing

1

0

High-throughput

0.458

High

711986

YL57
Putative zinc finger protein F44E2.7

1

0

High-throughput

0.458

High

1014759

SOR3
Sop-2-related protein 3

1

0

High-throughput

0.458

High

1095016

TM201
Transmembrane protein 201 homolog

1

0

High-throughput

0.458

High

1095335

Q23406
Nanos-type domain-containing protein

1

0

High-throughput

0.458

High

1212453

Q8IG64
Piwi domain-containing protein

1

0

High-throughput

0.458

High

1274665

Q93321
Non-specific serine/threonine protein kinase

1

0

High-throughput

0.458

High

1280041

HYLS1
Centriolar and ciliogenesis-associated protein hyls-1

1

0

High-throughput

0.458

High

110583

H2L2C8
Alpha-actinin, sarcomeric

1

9

High-throughput

0.439

High

86712

C6KRI9
Kinesin motor domain-containing protein

1

20

High-throughput

0.437

High

108277

G5EGG0
Uso1_p115_head domain-containing protein

1

15

High-throughput

0.437

High

109933

H2KZQ8
Protein transport protein sec16

1

6

High-throughput

0.437

High

183886

O16393
BZIP domain-containing protein

1

3

High-throughput

0.437

High

184482

PLDL
Probable phospholipase D F09G2.8

1

1

High-throughput

0.437

High

712409

SOR1
Sop-2-related protein 1

1

1

High-throughput

0.437

High

712438

SC161
Protein transport protein sec-16A.1

1

6

High-throughput

0.437

High

954285

P91176
CCHC-type domain-containing protein

1

9

High-throughput

0.437

High

999541

PTC1
Protein patched homolog 1

1

4

High-throughput

0.437

High

1013443

Q10050
Mitochondrial ornithine transporter 1

1

8

High-throughput

0.437

High

1090048

Q18403
WD_REPEATS_REGION domain-containing protein

1

13

High-throughput

0.437

High

1090831

Q19520
Minichromosome loss protein Mcl1 middle region domain-containing protein

1

12

High-throughput

0.437

High

1091050

STO2
Stomatin-2

1

6

High-throughput

0.437

High

1093716

HDA6
Histone deacetylase 6

1

7

High-throughput

0.437

High

1093974

P5CR
Putative pyrroline-5-carboxylate reductase

1

1

High-throughput

0.437

High

1094116

Q21205
SAM domain-containing protein

1

1

High-throughput

0.437

High

1103698

Q304D5
Thioredoxin domain-containing protein

1

5

High-throughput

0.437

High

1125704

Q5FC73
Uncharacterized protein

1

3

High-throughput

0.437

High

1150012

NU301
Nucleosome-remodeling factor subunit NURF301-like

1

16

High-throughput

0.437

High

1274735

Q93641
phosphatidylinositol-3-phosphatase

1

2

High-throughput

0.437

High

1276148

CLC91
C-type lectin domain-containing protein 91

1

1

High-throughput

0.437

High

1281011

SOP2
Polycomb protein sop-2

1

13

High-throughput

0.437

High

1353586

Q9U1Y6
Retinol dehydrogenase 13

1

1

High-throughput

0.437

High

1353603

Q9U2C2
Protein MCM10 homolog

1

1

High-throughput

0.437

High

1376849

Q9XVU8
Alpha-actinin, sarcomeric

1

7

High-throughput

0.417

High

1095435

HPO40
Hypersensitive to pore-forming toxin protein 40

1

0

High-throughput

0.251

Low

69075

A8XQE0
SANT_DAMP1_like domain-containing protein

1

0

High-throughput

0.249

Low

104015

G5EBK0
DEP domain-containing protein

1

0

High-throughput

0.249

Low

110199

H2L0A8
RRM domain-containing protein

1

0

High-throughput

0.249

Low

137620

PRI2
DNA primase large subunit

1

0

High-throughput

0.249

Low

220315

O45656
snRNA-activating protein complex subunit 3

1

0

High-throughput

0.249

Low

248129

O62263
Protein SZT2

1

0

High-throughput

0.249

Low

711247

CIDS1
CID domain-containing protein 1

1

0

High-throughput

0.249

Low

711883

YLU3
Uncharacterized protein F10E9.3

1

0

High-throughput

0.249

Low

836973

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.249

Low

954493

P91453
Uncharacterized protein

1

0

High-throughput

0.249

Low

1090163

Q18546
SAP domain-containing protein

1

0

High-throughput

0.249

Low

1093628

NPRL3
GATOR complex protein NPRL3

1

0

High-throughput

0.249

Low

1094489

Q21822
Intraflagellar transport protein 46 homolog

1

0

High-throughput

0.249

Low

1122565

Q564V2
Lateral Signaling Target

1

0

High-throughput

0.249

Low

1325804

Q9GYQ8
Sm domain-containing protein

1

0

High-throughput

0.249

Low

1353434

Q9TYM3
Protein aurora borealis

1

0

High-throughput

0.249

Low

1376848

Q9XUR4
F-box associated domain-containing protein

1

0

High-throughput

0.249

Low

1376850

Q9XX63
Coiled-coil domain-containing protein 69

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024