Protein: EREP1
Endosomal transmembrane epsin interactor 1 (Endosomal transmembrane binding with epsin)

Gene: EREP1, ENTREP1
Organism: Homo sapiens
Interactions: 122
UniProt ID: Q15884

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0022401 - negative adaptation of signaling pathway
GO:0031623 - receptor internalization
GO:0031901 - early endosome membrane
GO:0031902 - late endosome membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1079783

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

5

14

High-throughput

0.720

High

1079771

ITCH
E3 ubiquitin-protein ligase Itchy homolog

4

14

Small-scale

0.701

High

808136

NEDD4
E3 ubiquitin-protein ligase NEDD4

4

14

High-throughput

0.696

High

1079751

AN13D
Ankyrin repeat domain-containing protein 13D

4

3

Small-scale

0.692

High

125488

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

6

14

Small-scale

0.669

High

300349

AGRL1
Adhesion G protein-coupled receptor L1

3

1

High-throughput

0.667

High

1053360

FZD2
Frizzled-2

3

1

High-throughput

0.667

High

1079749

RHDF2
Inactive rhomboid protein 2

3

2

High-throughput

0.667

High

1079754

T179B
Transmembrane protein 179B

3

1

High-throughput

0.667

High

1079757

AN13A
Ankyrin repeat domain-containing protein 13A

3

3

High-throughput

0.667

High

1079759

SIDT2
SID1 transmembrane family member 2

3

1

High-throughput

0.667

High

1079778

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

3

1

High-throughput

0.667

High

1079779

S12A9
Solute carrier family 12 member 9

3

4

High-throughput

0.667

High

1079798

S12A6
Solute carrier family 12 member 6

3

4

High-throughput

0.667

High

1079800

KCNG1
Potassium voltage-gated channel subfamily G member 1

3

1

High-throughput

0.667

High

1079804

S12A4
Solute carrier family 12 member 4

3

4

High-throughput

0.667

High

299163

CSCL1
CSC1-like protein 1

3

0

High-throughput

0.638

High

839399

S26A2
Sulfate transporter

3

0

High-throughput

0.638

High

1079743

ANO6
Anoctamin-6

3

0

High-throughput

0.638

High

1079772

DNJC1
DnaJ homolog subfamily C member 1

3

0

High-throughput

0.638

High

1079789

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

3

0

High-throughput

0.638

High

927082

1433Z
14-3-3 protein zeta/delta

4

6

Small-scale

0.632

High

1079773

NED4L
E3 ubiquitin-protein ligase NEDD4-like

4

14

Small-scale

0.632

High

1079785

PCX3
Pecanex-like protein 3

4

1

Small-scale

0.632

High

1079795

HECW2
E3 ubiquitin-protein ligase HECW2

4

14

Small-scale

0.632

High

674607

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

2

3

High-throughput

0.611

High

275500

CAN15
Calpain-15

3

2

High-throughput

0.609

High

904606

1433G
14-3-3 protein gamma

3

6

High-throughput

0.609

High

1079752

STXB4
Syntaxin-binding protein 4

3

1

High-throughput

0.609

High

1079762

RHBL4
Rhomboid-related protein 4

3

2

High-throughput

0.609

High

1079792

CUED1
CUE domain-containing protein 1

3

1

High-throughput

0.609

High

1079794

WWOX
WW domain-containing oxidoreductase

3

1

High-throughput

0.609

High

1079807

RHBD3
Rhomboid domain-containing protein 3

3

4

High-throughput

0.609

High

277070

STAM2
Signal transducing adapter molecule 2

2

1

High-throughput

0.595

High

586037

SL9A1
Sodium/hydrogen exchanger 1

2

0

High-throughput

0.585

High

1079802

UBQL1
Ubiquilin-1

2

4

Small-scale

0.576

High

646924

1433T
14-3-3 protein theta

2

6

High-throughput

0.574

High

741147

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

2

1

High-throughput

0.558

High

1032774

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

1

High-throughput

0.558

High

1025401

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

4

High-throughput

0.543

High

1023279

TRI32
E3 ubiquitin-protein ligase TRIM32

2

1

Small-scale

0.526

High

324419

BAG3
BAG family molecular chaperone regulator 3

2

2

Small-scale

0.526

High

1079811

EPN1
Epsin-1

1

2

Small-scale

0.506

High

683375

1433B
14-3-3 protein beta/alpha

1

6

High-throughput

0.489

High

1079769

OPTN
Optineurin

1

0

High-throughput

0.486

High

567077

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

734410

CXG1
Gap junction gamma-1 protein

1

1

High-throughput

0.479

High

873925

S12A2
Solute carrier family 12 member 2

1

4

High-throughput

0.479

High

1079746

S27A3
Long-chain fatty acid transport protein 3

1

1

High-throughput

0.479

High

1079775

ABCA3
Phospholipid-transporting ATPase ABCA3

1

1

High-throughput

0.479

High

1079781

TTYH3
Protein tweety homolog 3

1

1

High-throughput

0.479

High

1079768

ASTRA
Protein Aster-A

1

0

High-throughput

0.458

High

1079786

S40A1
Solute carrier family 40 member 1

1

0

Small-scale

0.458

High

128861

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

Small-scale

0.457

High

135782

P3C2B
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

1

1

Small-scale

0.457

High

307534

EPN2
Epsin-2

1

2

Small-scale

0.457

High

319854

HERC2
E3 ubiquitin-protein ligase HERC2

1

15

Small-scale

0.457

High

475037

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

Small-scale

0.457

High

475819

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

Small-scale

0.457

High

924011

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

2

Small-scale

0.457

High

924309

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

Small-scale

0.457

High

1079776

UBAC1
Ubiquitin-associated domain-containing protein 1

1

4

Small-scale

0.457

High

684058

1433S
14-3-3 protein sigma

1

6

High-throughput

0.439

High

979302

UBXN1
UBX domain-containing protein 1

1

5

High-throughput

0.439

High

1079755

TAXB1
Tax1-binding protein 1

1

4

High-throughput

0.439

High

1079744

GRAP1
GRIP1-associated protein 1

1

0

Small-scale

0.438

High

1079780

UBXN6
UBX domain-containing protein 6

1

0

Small-scale

0.438

High

1079801

MYO6
Unconventional myosin-VI

1

0

Small-scale

0.438

High

315193

CNEP1
CTD nuclear envelope phosphatase 1

1

1

High-throughput

0.437

High

373119

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

1

1

High-throughput

0.437

High

1065035

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

15

High-throughput

0.437

High

1079760

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.437

High

1079787

ST7
Suppressor of tumorigenicity 7 protein

1

2

High-throughput

0.437

High

304181

UBR5
E3 ubiquitin-protein ligase UBR5

1

15

Small-scale

0.417

High

800587

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

1

Small-scale

0.417

High

1079748

WWC2
Protein WWC2

1

14

Small-scale

0.417

High

1079753

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

14

Small-scale

0.417

High

1079765

SYNE2
Nesprin-2

1

1

Small-scale

0.417

High

1079766

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

1

Small-scale

0.417

High

1079788

UBQL4
Ubiquilin-4

1

4

Small-scale

0.417

High

1079791

RN216
E3 ubiquitin-protein ligase RNF216

1

2

Small-scale

0.417

High

1079803

POLI
DNA polymerase iota

1

1

Small-scale

0.417

High

1079805

POLH
DNA polymerase eta

1

1

Small-scale

0.417

High

1079810

ARI1
E3 ubiquitin-protein ligase ARIH1

1

2

Small-scale

0.417

High

946390

EREP3
Protein ENTREP3

3

0

High-throughput

0.347

High

1079750

TMPPE
Transmembrane protein with metallophosphoesterase domain

3

0

High-throughput

0.347

High

1079758

GHDC
GH3 domain-containing protein

3

0

High-throughput

0.347

High

1079761

TBC15
TBC1 domain family member 15

3

0

High-throughput

0.347

High

1079763

CHPT1
Cholinephosphotransferase 1

3

0

High-throughput

0.347

High

1079793

CLDN1
Claudin domain-containing protein 1

3

0

High-throughput

0.347

High

1079777

CA043
Protein C1orf43

2

0

High-throughput

0.328

High

421321

HYEP
Epoxide hydrolase 1

2

0

High-throughput

0.318

High

725793

SOAT1
Sterol O-acyltransferase 1

2

0

High-throughput

0.318

High

1079790

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

2

0

High-throughput

0.318

High

1079806

KLH20
Kelch-like protein 20

2

0

High-throughput

0.318

High

909598

1433E
14-3-3 protein epsilon

2

0

Small-scale

0.316

High

1079796

WRP73
WD repeat-containing protein WRAP73

1

0

High-throughput

0.279

Low

69477

UPK3L
Uroplakin-3b-like protein 1

1

0

High-throughput

0.249

Low

174208

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.249

Low

552827

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

651310

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

720562

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1079742

CP51A
Lanosterol 14-alpha demethylase

1

0

High-throughput

0.249

Low

1079745

MBRL
Membralin

1

0

High-throughput

0.249

Low

1079764

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.249

Low

1079797

FA8A1
Protein FAM8A1

1

0

High-throughput

0.249

Low

1079809

TBL2
Transducin beta-like protein 2

1

0

High-throughput

0.249

Low

165313

KHNYN
Protein KHNYN

1

0

Small-scale

0.238

Low

316334

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

Small-scale

0.238

Low

641419

PAX6
Paired box protein Pax-6

1

0

Small-scale

0.238

Low

966550

OTUD4
OTU domain-containing protein 4

1

0

Small-scale

0.238

Low

1063813

TNIP1
TNFAIP3-interacting protein 1

1

0

Small-scale

0.238

Low

1079720

USF2
Upstream stimulatory factor 2

1

0

Small-scale

0.238

Low

1079747

RN123
E3 ubiquitin-protein ligase RNF123

1

0

Small-scale

0.238

Low

1079756

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.238

Low

1079767

CC127
Coiled-coil domain-containing protein 127

1

0

Small-scale

0.238

Low

1079770

DCNL1
DCN1-like protein 1

1

0

Small-scale

0.238

Low

1079774

UIMC1
BRCA1-A complex subunit RAP80

1

0

Small-scale

0.238

Low

1079782

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

Small-scale

0.238

Low

1079784

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

Small-scale

0.238

Low

1079799

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

Small-scale

0.238

Low

1079808

RN115
E3 ubiquitin-protein ligase RNF115

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024