Protein: THOC5
THO complex subunit 5 homolog (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90)

Gene: THOC5
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q13769

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000347 - THO complex
GO:0000445 - THO complex part of transcription export complex
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1045271

THOC1
THO complex subunit 1

9

1

Small-scale

0.973

High

1045254

THOC7
THO complex subunit 7 homolog

3

2

Small-scale

0.861

High

1045244

DX39B
Spliceosome RNA helicase DDX39B

7

3

Small-scale

0.751

High

1045259

THOC4
THO complex subunit 4

6

2

Small-scale

0.734

High

1045263

THOC2
THO complex subunit 2

6

2

Small-scale

0.722

High

1045273

THOC3
THO complex subunit 3

5

3

Small-scale

0.718

High

1045252

NCBP3
Nuclear cap-binding protein subunit 3

3

0

High-throughput

0.616

High

1045261

THOC6
THO complex subunit 6 homolog

2

2

Small-scale

0.611

High

856673

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

1045297

CHTOP
Chromatin target of PRMT1 protein

2

0

Small-scale

0.585

High

1045292

NXF1
Nuclear RNA export factor 1

2

0

Small-scale

0.560

High

934156

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.545

High

117137

DX39A
ATP-dependent RNA helicase DDX39A

1

3

High-throughput

0.536

High

508513

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

557122

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

1045282

PDIP3
Polymerase delta-interacting protein 3

1

2

High-throughput

0.536

High

836832

DNLI4
DNA ligase 4

1

0

High-throughput

0.529

High

388425

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

69513

MYO1G
Unconventional myosin-Ig [Cleaved into: Minor histocompatibility antigen HA-2

1

0

High-throughput

0.513

High

256508

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

446625

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

448649

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

538950

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

722406

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.513

High

722602

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.513

High

757605

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.513

High

801131

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

805668

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

948868

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.513

High

973063

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.513

High

977885

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.513

High

996659

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1045246

RBM39
RNA-binding protein 39

1

0

High-throughput

0.513

High

1045249

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1045251

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1045256

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

High-throughput

0.513

High

1045257

WDR74
WD repeat-containing protein 74

1

0

High-throughput

0.513

High

1045262

CS047
Uncharacterized protein C19orf47

1

0

High-throughput

0.513

High

1045264

RT27
Small ribosomal subunit protein mS27

1

0

High-throughput

0.513

High

1045267

MGN2
Protein mago nashi homolog 2

1

0

High-throughput

0.513

High

1045269

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

High-throughput

0.513

High

1045270

RBM33
RNA-binding protein 33

1

0

High-throughput

0.513

High

1045276

SPB12
Serpin B12

1

0

High-throughput

0.513

High

1045277

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

1045280

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.513

High

1045288

BCLF1
Bcl-2-associated transcription factor 1

1

0

High-throughput

0.513

High

912152

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

1

High-throughput

0.508

High

216928

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.489

High

1045274

ZN830
Zinc finger protein 830

1

0

High-throughput

0.486

High

1045295

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

0

High-throughput

0.486

High

569703

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

726807

FUS
RNA-binding protein FUS

1

2

High-throughput

0.479

High

959406

VIGLN
Vigilin

1

1

High-throughput

0.479

High

1045248

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1045266

RBP56
TATA-binding protein-associated factor 2N

1

1

High-throughput

0.479

High

1045272

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.479

High

209968

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

227402

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

233432

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

244411

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

319829

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

322595

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

374203

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

379382

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.458

High

442144

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

552682

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

651159

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

720417

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

801875

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.458

High

908508

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

917239

H4
Histone H4

1

0

High-throughput

0.458

High

998045

NCBP1
Nuclear cap-binding protein subunit 1

1

0

Small-scale

0.458

High

1045250

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1045258

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1045265

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1045268

FUBP1
Far upstream element-binding protein 1

1

0

High-throughput

0.458

High

1045278

NEB2
Neurabin-2

1

0

High-throughput

0.458

High

1045279

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

1045281

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

1045284

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1045285

ANLN
Anillin

1

0

High-throughput

0.458

High

1045286

DJC17
DnaJ homolog subfamily C member 17

1

0

High-throughput

0.458

High

1045287

AATF
Protein AATF

1

0

High-throughput

0.458

High

1045289

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1045290

LUZP4
Leucine zipper protein 4

1

0

Small-scale

0.458

High

1045293

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1045294

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

0

High-throughput

0.458

High

92359

E9PB61
Aly/REF export factor

1

2

High-throughput

0.445

High

1045275

CF418
Cilia- and flagella-associated protein 418

1

0

Small-scale

0.438

High

1045260

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.437

High

1045283

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

236497

NEMF
Ribosome quality control complex subunit NEMF

1

0

High-throughput

0.426

High

787229

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.426

High

853886

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.426

High

1045245

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1045247

CASP8
Caspase-8

1

0

High-throughput

0.426

High

1045253

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

102435

G3V529
ATP-dependent RNA helicase

1

1

High-throughput

0.407

High

108792

H0Y714
IMP U3 small nucleolar ribonucleoprotein 4

1

1

High-throughput

0.407

High

108795

H0Y7U4
THO complex subunit 2

1

1

High-throughput

0.407

High

976717

TAP1
Antigen peptide transporter 1

1

0

Small-scale

0.288

High

674898

OXYR
Oxytocin receptor

1

0

High-throughput

0.282

High

314870

FMNL1
Formin-like protein 1

1

0

High-throughput

0.279

Low

957100

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

0

High-throughput

0.279

Low

1045291

NHSL3
NHS-like protein 3

1

0

High-throughput

0.279

Low

1045296

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.279

Low

100748

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

148785

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

1045255

ANO7
Anoctamin-7

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024