Protein: PHC1
Polyhomeotic-like protein 1 (hPH1) (Early development regulatory protein 1)

Gene: PHC1
Organism: Homo sapiens
Interactions: 76
UniProt ID: P78364

Gene Ontology (top 5):
GO:0001739 - sex chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

943073

PHC2
Polyhomeotic-like protein 2

8

18

Small-scale

0.971

High

943082

SCMH1
Polycomb protein SCMH1

4

18

High-throughput

0.903

High

943098

SCML1
Sex comb on midleg-like protein 1

4

18

High-throughput

0.903

High

943067

SMBT2
Scm-like with four MBT domains protein 2

4

18

High-throughput

0.902

High

943078

PHC3
Polyhomeotic-like protein 3

4

18

High-throughput

0.895

High

934086

CSK21
Casein kinase II subunit alpha

2

15

High-throughput

0.811

High

943089

SDCB2
Syntenin-2

2

7

High-throughput

0.783

High

717684

BMI1
Polycomb complex protein BMI-1

12

20

Small-scale

0.759

High

718390

PCGF2
Polycomb group RING finger protein 2

11

20

Small-scale

0.758

High

123234

CBX4
E3 SUMO-protein ligase CBX4

10

20

Small-scale

0.754

High

943084

RING2
E3 ubiquitin-protein ligase RING2

7

20

Small-scale

0.752

High

943094

CBX8
Chromobox protein homolog 8

6

20

High-throughput

0.738

High

943060

RING1
E3 ubiquitin-protein ligase RING1

6

20

Small-scale

0.736

High

943062

CBX2
Chromobox protein homolog 2

6

20

Small-scale

0.733

High

316005

CBX6
Chromobox protein homolog 6

5

20

High-throughput

0.718

High

327838

CBX7
Chromobox protein homolog 7

4

20

High-throughput

0.704

High

943097

SMBT1
Scm-like with four MBT domains protein 1

1

19

High-throughput

0.698

High

943064

PCGF3
Polycomb group RING finger protein 3

3

20

High-throughput

0.653

High

943059

PHC1
Polyhomeotic-like protein 1

1

18

High-throughput

0.621

High

586680

CSK22
Casein kinase II subunit alpha'

1

15

High-throughput

0.618

High

940773

RNF4
E3 ubiquitin-protein ligase RNF4

2

1

High-throughput

0.606

High

918285

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

943095

TRPM3
Transient receptor potential cation channel subfamily M member 3

2

3

High-throughput

0.574

High

315927

NPTXR
Neuronal pentraxin receptor

2

8

High-throughput

0.558

High

930138

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.541

High

871526

HSP72
Heat shock-related 70 kDa protein 2

1

3

High-throughput

0.536

High

943063

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

943083

RBM14
RNA-binding protein 14

1

3

High-throughput

0.536

High

943085

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.536

High

943068

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.529

High

943099

NFS1
Cysteine desulfurase

1

0

High-throughput

0.513

High

905829

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

Small-scale

0.508

High

358743

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.501

High

323684

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.489

High

363063

FINC
Fibronectin

1

3

High-throughput

0.489

High

943091

PAAT
ATPase PAAT

1

1

High-throughput

0.489

High

278263

PIAS2
E3 SUMO-protein ligase PIAS2

1

4

High-throughput

0.481

High

617282

SP100
Nuclear autoantigen Sp-100

1

20

High-throughput

0.481

High

737738

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

Small-scale

0.481

High

928059

SUMO1
Small ubiquitin-related modifier 1

1

9

High-throughput

0.481

High

943071

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

5

High-throughput

0.481

High

943076

ZCHC7
Zinc finger CCHC domain-containing protein 7

1

3

High-throughput

0.481

High

943090

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

2

High-throughput

0.481

High

244272

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

265630

E2F6
Transcription factor E2F6

1

18

High-throughput

0.479

High

268019

EED
Polycomb protein EED

1

18

High-throughput

0.479

High

386505

P53
Cellular tumor antigen p53

1

7

Small-scale

0.479

High

455317

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.479

High

798851

GATA4
Transcription factor GATA-4

1

12

High-throughput

0.479

High

802420

ATRX
Transcriptional regulator ATRX

1

12

Small-scale

0.479

High

928867

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.479

High

934644

H31
Histone H3.1

1

20

High-throughput

0.479

High

943061

MDC1
Mediator of DNA damage checkpoint protein 1

1

13

High-throughput

0.479

High

943065

BCORL
BCL-6 corepressor-like protein 1

1

17

High-throughput

0.479

High

943069

BCOR
BCL-6 corepressor

1

13

High-throughput

0.479

High

943070

PCGF5
Polycomb group RING finger protein 5

1

20

High-throughput

0.479

High

943072

MGAP
MAX gene-associated protein

1

10

High-throughput

0.479

High

943074

YAF2
YY1-associated factor 2

1

9

High-throughput

0.479

High

943077

RYBP
RING1 and YY1-binding protein

1

9

High-throughput

0.479

High

943079

KDM2B
Lysine-specific demethylase 2B

1

9

High-throughput

0.479

High

943080

HDAC2
Histone deacetylase 2

1

17

High-throughput

0.479

High

943081

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

16

High-throughput

0.479

High

943087

PCGF1
Polycomb group RING finger protein 1

1

20

High-throughput

0.479

High

943088

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.479

High

943092

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.479

High

943096

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

4

High-throughput

0.479

High

943086

MESP1
Mesoderm posterior protein 1

1

0

Small-scale

0.458

High

503880

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.457

High

843609

FXR1
RNA-binding protein FXR1

1

8

High-throughput

0.457

High

69543

B0QXZ6
Chromobox 6

1

20

High-throughput

0.445

High

943066

Q5T8Z6
Polycomb complex protein BMI-1

1

20

High-throughput

0.445

High

100673

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

943093

FBRS
Probable fibrosin-1

1

3

High-throughput

0.437

High

943075

FAM9A
Protein FAM9A

2

0

High-throughput

0.316

High

344482

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024