Protein: CDK13
Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13) (hCDK13) (Cholinesterase-related cell division controller)

Gene: CDK13
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q14004

Gene Ontology (top 5):
GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0002945 - cyclin K-CDK13 complex
GO:0003723 - RNA binding
GO:0004672 - protein kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

277500

CCNK
Cyclin-K

7

20

Small-scale

0.968

High

431840

HS90A
Heat shock protein HSP 90-alpha

4

20

High-throughput

0.903

High

438162

HS90B
Heat shock protein HSP 90-beta

4

20

High-throughput

0.903

High

1034845

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

4

18

High-throughput

0.903

High

851381

NEK3
Serine/threonine-protein kinase Nek3

3

15

High-throughput

0.861

High

1047609

DUSTY
Dual serine/threonine and tyrosine protein kinase

3

13

High-throughput

0.861

High

1047624

RBM14
RNA-binding protein 14

3

11

High-throughput

0.861

High

1047638

CDK12
Cyclin-dependent kinase 12

3

18

High-throughput

0.861

High

942646

SRPK2
SRSF protein kinase 2

3

19

High-throughput

0.853

High

1047599

CDC37
Hsp90 co-chaperone Cdc37

3

10

High-throughput

0.847

High

515430

CDK4
Cyclin-dependent kinase 4

2

17

High-throughput

0.811

High

625422

CDK2
Cyclin-dependent kinase 2

2

14

High-throughput

0.811

High

992767

SRSF1
Serine/arginine-rich splicing factor 1

2

20

Small-scale

0.799

High

1047593

PLSI
Plastin-1

2

16

High-throughput

0.789

High

1047603

LARP7
La-related protein 7

2

18

High-throughput

0.789

High

1047604

H90B4
Putative heat shock protein HSP 90-beta 4

2

20

High-throughput

0.712

High

1047606

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.712

High

1047607

HS904
Putative heat shock protein HSP 90-alpha A4

2

20

High-throughput

0.712

High

118731

AIP
AH receptor-interacting protein

1

14

High-throughput

0.691

High

414911

CDK1
Cyclin-dependent kinase 1

1

14

High-throughput

0.691

High

801133

KI67
Proliferation marker protein Ki-67

1

8

High-throughput

0.691

High

841715

CDK9
Cyclin-dependent kinase 9

1

16

High-throughput

0.691

High

951961

SRSF3
Serine/arginine-rich splicing factor 3

1

20

High-throughput

0.691

High

993714

SRSF4
Serine/arginine-rich splicing factor 4

1

20

High-throughput

0.691

High

1028651

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.691

High

1028903

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.691

High

1047619

PSPC1
Paraspeckle component 1

1

17

High-throughput

0.691

High

1047628

ZNF2
Zinc finger protein 2

1

2

High-throughput

0.691

High

1047648

SRPK3
SRSF protein kinase 3

1

19

High-throughput

0.691

High

414279

RB
Retinoblastoma-associated protein

3

15

High-throughput

0.667

High

933442

TBA4A
Tubulin alpha-4A chain

3

15

High-throughput

0.667

High

1047590

KEAP1
Kelch-like ECH-associated protein 1

3

1

High-throughput

0.667

High

1047608

SPSB3
SPRY domain-containing SOCS box protein 3

3

12

High-throughput

0.667

High

1047633

FBX44
F-box only protein 44

3

3

High-throughput

0.667

High

990052

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

3

2

Small-scale

0.660

High

1047613

FBX11
F-box only protein 11

3

0

High-throughput

0.638

High

338409

EGFR
Epidermal growth factor receptor

1

13

High-throughput

0.618

High

374211

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.618

High

384813

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

779384

CCNF
Cyclin-F

1

20

High-throughput

0.618

High

932147

ACTC
Actin, alpha cardiac muscle 1

1

8

High-throughput

0.618

High

1047592

DHX8
ATP-dependent RNA helicase DHX8

1

5

High-throughput

0.618

High

1047616

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.618

High

1047626

BARD1
BRCA1-associated RING domain protein 1

1

11

High-throughput

0.618

High

1047646

HECD1
E3 ubiquitin-protein ligase HECTD1

1

14

High-throughput

0.618

High

1047647

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.618

High

428202

TBB5
Tubulin beta chain

2

14

High-throughput

0.611

High

933805

TBB4B
Tubulin beta-4B chain

2

14

High-throughput

0.611

High

1047611

TBA1A
Tubulin alpha-1A chain

2

15

High-throughput

0.611

High

1047601

EDRF1
Erythroid differentiation-related factor 1

2

0

High-throughput

0.585

High

1047645

PALD
Paladin

2

0

High-throughput

0.585

High

1047605

H90B3
Putative heat shock protein HSP 90-beta-3

1

20

High-throughput

0.575

High

369575

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1047602

TBB8
Tubulin beta-8 chain

2

14

High-throughput

0.558

High

180313

MAGB2
Melanoma-associated antigen B2

1

4

High-throughput

0.536

High

381203

TBB4A
Tubulin beta-4A chain

1

14

High-throughput

0.536

High

400895

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.536

High

489035

H14
Histone H1.4

1

20

High-throughput

0.536

High

531149

EF2
Elongation factor 2

1

8

High-throughput

0.536

High

559094

H15
Histone H1.5

1

20

High-throughput

0.536

High

616309

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.536

High

642343

RL13
Large ribosomal subunit protein eL13

1

4

High-throughput

0.536

High

685946

ARRB2
Beta-arrestin-2

1

5

High-throughput

0.536

High

736454

RL4
Large ribosomal subunit protein uL4

1

4

High-throughput

0.536

High

773359

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

826656

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.536

High

858622

PPP5
Serine/threonine-protein phosphatase 5

1

18

High-throughput

0.536

High

907905

RS16
Small ribosomal subunit protein uS9

1

3

High-throughput

0.536

High

909547

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.536

High

916185

RL23A
Large ribosomal subunit protein uL23

1

5

High-throughput

0.536

High

1040550

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.536

High

1047591

FGFP1
Fibroblast growth factor-binding protein 1

1

1

High-throughput

0.536

High

1047618

DDX54
ATP-dependent RNA helicase DDX54

1

9

High-throughput

0.536

High

1047643

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.536

High

1047644

PURG
Purine-rich element-binding protein gamma

1

3

High-throughput

0.536

High

1047649

SGT1
Protein SGT1 homolog

1

8

High-throughput

0.536

High

1047650

MYO5A
Unconventional myosin-Va

1

14

High-throughput

0.536

High

1047652

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.536

High

831310

CEBPA
CCAAT/enhancer-binding protein alpha

1

15

High-throughput

0.527

High

1047600

H31T
Histone H3.1t

1

7

High-throughput

0.515

High

246109

RNH1
Ribonuclease H1

1

0

High-throughput

0.513

High

451899

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.513

High

1047639

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.513

High

1047651

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.513

High

263623

PR40A
Pre-mRNA-processing factor 40 homolog A

1

12

High-throughput

0.508

High

1047630

CHM4A
Charged multivesicular body protein 4a

1

4

High-throughput

0.508

High

130501

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.489

High

778142

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

5

High-throughput

0.489

High

1047596

K1H1
Keratin, type I cuticular Ha1

1

5

High-throughput

0.481

High

1047631

TRIM7
E3 ubiquitin-protein ligase TRIM7

1

5

High-throughput

0.481

High

171772

WDR46
WD repeat-containing protein 46

1

13

High-throughput

0.479

High

244418

BRD4
Bromodomain-containing protein 4

1

13

High-throughput

0.479

High

268465

BAF
Barrier-to-autointegration factor

1

1

High-throughput

0.479

High

303225

HEXI1
Protein HEXIM1

1

11

High-throughput

0.479

High

379387

MYCN
N-myc proto-oncogene protein

1

16

High-throughput

0.479

High

472857

H2AB2
Histone H2A-Bbd type 2/3

1

9

High-throughput

0.479

High

552690

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.479

High

569709

CEBPB
CCAAT/enhancer-binding protein beta

1

15

High-throughput

0.479

High

583476

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

606420

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.479

High

651168

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

7

High-throughput

0.479

High

720426

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

742289

SYUA
Alpha-synuclein

1

5

High-throughput

0.479

High

869635

TERF1
Telomeric repeat-binding factor 1

1

15

High-throughput

0.479

High

906450

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

16

High-throughput

0.479

High

917245

H4
Histone H4

1

6

High-throughput

0.479

High

921561

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

8

High-throughput

0.479

High

928906

SKP1
S-phase kinase-associated protein 1

1

7

High-throughput

0.479

High

934747

H31
Histone H3.1

1

7

High-throughput

0.479

High

1026406

RFA4
Replication protein A 30 kDa subunit

1

10

High-throughput

0.479

High

1037223

TBB3
Tubulin beta-3 chain

1

14

High-throughput

0.479

High

1047594

TNIP1
TNFAIP3-interacting protein 1

1

16

High-throughput

0.479

High

1047595

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

8

High-throughput

0.479

High

1047597

TERF2
Telomeric repeat-binding factor 2

1

17

High-throughput

0.479

High

1047598

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

1047610

MOB3C
MOB kinase activator 3C

1

4

High-throughput

0.479

High

1047612

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1047620

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1047621

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

10

High-throughput

0.479

High

1047625

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1047627

TBA1C
Tubulin alpha-1C chain

1

15

High-throughput

0.479

High

1047629

DDX23
Probable ATP-dependent RNA helicase DDX23

1

9

High-throughput

0.479

High

1047632

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

7

High-throughput

0.479

High

1047635

RC3H2
Roquin-2

1

11

High-throughput

0.479

High

1047637

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

2

High-throughput

0.479

High

1047641

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

4

High-throughput

0.479

High

1047642

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

182744

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

1047622

CHMP6
Charged multivesicular body protein 6

1

4

High-throughput

0.457

High

1047640

CHMP5
Charged multivesicular body protein 5

1

4

High-throughput

0.457

High

1047634

LN28A
Protein lin-28 homolog A

1

9

High-throughput

0.445

High

1047636

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1047615

TTC9C
Tetratricopeptide repeat protein 9C

1

15

High-throughput

0.437

High

1047617

LNX1
E3 ubiquitin-protein ligase LNX

1

8

Small-scale

0.437

High

69581

B0UZZ8
Chromosome 6 open reading frame 11

1

13

High-throughput

0.407

High

1047623

JPH4
Junctophilin-4

2

0

High-throughput

0.328

High

1047614

TRM44
Probable tRNA

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024