Protein: RN170
E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170)

Gene: RN170, RNF170
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q96K19

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0034140 - negative regulation of toll-like receptor 3 signaling pathway
GO:0046872 - metal ion binding
GO:0061630 - ubiquitin protein ligase activity
GO:0070936 - protein K48-linked ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919828

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

1

Small-scale

0.778

High

299971

ERLN2
Erlin-2

4

3

Small-scale

0.694

High

266229

ERLN1
Erlin-1

3

3

High-throughput

0.667

High

1295770

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

2

0

Small-scale

0.660

High

1202352

RETR3
Reticulophagy regulator 3

3

0

High-throughput

0.638

High

1138904

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

2

High-throughput

0.625

High

1295767

RN170
E3 ubiquitin-protein ligase RNF170

1

0

Small-scale

0.614

High

1295773

P2Y12
P2Y purinoceptor 12

3

2

High-throughput

0.609

High

1032797

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

2

0

High-throughput

0.602

High

1152576

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

2

0

High-throughput

0.602

High

1295775

RDH14
Retinol dehydrogenase 14

2

0

High-throughput

0.602

High

1295778

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

2

0

High-throughput

0.602

High

874676

BI1
Bax inhibitor 1

2

0

High-throughput

0.585

High

1056305

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

2

2

Small-scale

0.584

High

69683

HACD1
Very-long-chain

2

0

High-throughput

0.580

High

1060101

STAR3
StAR-related lipid transfer protein 3

2

0

High-throughput

0.580

High

1221937

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

0

High-throughput

0.580

High

932561

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

2

High-throughput

0.579

High

213626

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

2

High-throughput

0.553

High

1290146

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

2

High-throughput

0.553

High

179953

TLR3
Toll-like receptor 3

1

0

Small-scale

0.537

High

1295780

UBQL2
Ubiquilin-2

1

0

High-throughput

0.517

High

1016093

SRBP2
Sterol regulatory element-binding protein 2

1

0

High-throughput

0.513

High

849699

CCR6
C-C chemokine receptor type 6

1

1

High-throughput

0.489

High

1031053

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

1

High-throughput

0.489

High

1055773

ITPR3
Inositol 1,4,5-trisphosphate receptor type 3

1

2

High-throughput

0.479

High

1292340

RN185
E3 ubiquitin-protein ligase RNF185

1

2

High-throughput

0.479

High

1069152

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.458

High

1120980

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.458

High

1165863

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1295302

TMX3
Protein disulfide-isomerase TMX3

1

0

High-throughput

0.458

High

1295781

AMFR
E3 ubiquitin-protein ligase AMFR

1

0

High-throughput

0.458

High

1295782

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.458

High

1255498

ST7L
Suppressor of tumorigenicity 7 protein-like

2

0

High-throughput

0.328

High

1295777

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

2

0

High-throughput

0.328

High

1268627

LPAR1
Lysophosphatidic acid receptor 1

2

0

High-throughput

0.318

High

131944

UPK2
Uroplakin-2

2

0

High-throughput

0.316

High

1124490

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.316

High

1130999

SNP47
Synaptosomal-associated protein 47

2

0

High-throughput

0.316

High

1252077

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

2

0

High-throughput

0.316

High

1295768

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

2

0

High-throughput

0.316

High

1295769

TM109
Voltage-gated monoatomic cation channel TMEM109

2

0

High-throughput

0.316

High

893729

PSA6
Proteasome subunit alpha type-6

1

0

High-throughput

0.299

High

217046

PRIC3
Prickle planar cell polarity protein 3

1

0

High-throughput

0.279

Low

724966

MYH9
Myosin-9

1

0

High-throughput

0.279

Low

814300

GLR
Glucagon receptor

1

0

High-throughput

0.279

Low

846575

DUS3
Dual specificity protein phosphatase 3

1

0

High-throughput

0.279

Low

895013

RAB4B
Ras-related protein Rab-4B

1

0

High-throughput

0.279

Low

1266799

TM9S4
Transmembrane 9 superfamily member 4

1

0

High-throughput

0.279

Low

1295771

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.279

Low

1295774

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.279

Low

1295776

AT132
Polyamine-transporting ATPase 13A2

1

0

High-throughput

0.279

Low

277390

GABR2
Gamma-aminobutyric acid type B receptor subunit 2

1

0

High-throughput

0.269

Low

1295772

FXYD6
FXYD domain-containing ion transport regulator 6

1

0

High-throughput

0.251

Low

205839

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

416494

S10A9
Protein S100-A9

1

0

High-throughput

0.249

Low

822501

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.249

Low

897292

CSN2
COP9 signalosome complex subunit 2

1

0

High-throughput

0.249

Low

1190595

CF120
UPF0669 protein C6orf120

1

0

High-throughput

0.249

Low

1240526

ATAD1
Outer mitochondrial transmembrane helix translocase

1

0

High-throughput

0.249

Low

1295779

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024