Protein: CO6A1
Collagen alpha-1(VI) chain

Gene: CO6A1, COL6A1
Organism: Homo sapiens
Interactions: 94
UniProt ID: P12109

Gene Ontology (top 5):
GO:0000302 - response to reactive oxygen species
GO:0000902 - cell morphogenesis
GO:0001649 - osteoblast differentiation
GO:0001942 - hair follicle development
GO:0002023 - reduction of food intake in response to dietary excess

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

473739

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

3

20

High-throughput

0.861

High

517919

CO9A1

3

16

High-throughput

0.861

High

517968

COL11
Collectin-11

3

18

High-throughput

0.861

High

70501

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

20

High-throughput

0.691

High

158892

NCTR3
Natural cytotoxicity triggering receptor 3

1

1

High-throughput

0.691

High

362578

C1QC
Complement C1q subcomponent subunit C

1

20

High-throughput

0.691

High

517915

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.691

High

517924

CO8A2
Collagen alpha-2(VIII) chain

1

19

High-throughput

0.691

High

517969

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

20

High-throughput

0.691

High

517970

C1QT2
Complement C1q tumor necrosis factor-related protein 2

1

20

High-throughput

0.691

High

517980

COLQ
Acetylcholinesterase collagenic tail peptide

1

17

High-throughput

0.691

High

517981

PRG3
Proteoglycan 3

1

5

High-throughput

0.691

High

517944

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

2

High-throughput

0.667

High

429262

PGS2
Decorin

1

3

Small-scale

0.647

High

434610

TSP1
Thrombospondin-1

1

7

Small-scale

0.647

High

517922

PGS1
Biglycan

1

3

Small-scale

0.647

High

517929

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

17

Small-scale

0.647

High

517966

RTBDN
Retbindin

3

0

High-throughput

0.638

High

135838

WNT7A
Protein Wnt-7a

2

5

High-throughput

0.628

High

180678

PA2GX
Group 10 secretory phospholipase A2

2

2

High-throughput

0.628

High

439221

MMP2
72 kDa type IV collagenase

2

13

High-throughput

0.628

High

517917

MMP9
Matrix metalloproteinase-9

2

13

High-throughput

0.628

High

517940

DEF1
Neutrophil defensin 1

2

1

High-throughput

0.628

High

517941

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

20

High-throughput

0.628

High

517955

LYZL1
Lysozyme-like protein 1

2

4

High-throughput

0.628

High

517961

LYPD1
Ly6/PLAUR domain-containing protein 1

2

1

High-throughput

0.628

High

517982

INSL5
Insulin-like peptide INSL5

2

2

High-throughput

0.628

High

517920

CO5A1

1

18

Small-scale

0.590

High

517959

SFPA2
Pulmonary surfactant-associated protein A2

1

20

High-throughput

0.575

High

350949

PDGFB
Platelet-derived growth factor subunit B

1

9

Small-scale

0.536

High

237019

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

20

High-throughput

0.536

High

279235

LYZL6
Lysozyme-like protein 6

1

4

High-throughput

0.536

High

389434

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.536

High

474688

CFC1
Cryptic protein

1

1

High-throughput

0.536

High

517916

EDN3
Endothelin-3

1

1

High-throughput

0.536

High

517932

WNT5A
Protein Wnt-5a

1

5

High-throughput

0.536

High

517935

VEGFB
Vascular endothelial growth factor B

1

9

High-throughput

0.536

High

517939

WNT4
Protein Wnt-4

1

5

High-throughput

0.536

High

517942

OS9
Protein OS-9

1

1

High-throughput

0.536

High

517945

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.536

High

517948

TAZ
Tafazzin

1

1

High-throughput

0.536

High

517949

CCL15
C-C motif chemokine 15

1

3

High-throughput

0.536

High

517950

DB136
Defensin beta 136

1

1

High-throughput

0.536

High

517951

DB135
Beta-defensin 135

1

1

High-throughput

0.536

High

517953

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

9

High-throughput

0.536

High

517958

LYZL2
Lysozyme-like protein 2

1

4

High-throughput

0.536

High

517960

GT252
Procollagen galactosyltransferase 2

1

20

High-throughput

0.536

High

517962

DB125
Beta-defensin 125

1

1

High-throughput

0.536

High

517971

WN10A
Protein Wnt-10a

1

5

High-throughput

0.536

High

517973

IL25
Interleukin-25

1

1

High-throughput

0.536

High

517979

PA2GD
Group IID secretory phospholipase A2

1

2

High-throughput

0.536

High

517974

FBX6
F-box only protein 6

2

5

High-throughput

0.533

High

319503

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

351915

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.513

High

454073

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.513

High

517918

NTF3
Neurotrophin-3

1

0

High-throughput

0.513

High

517928

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.513

High

517931

LEP
Leptin

1

0

High-throughput

0.513

High

517938

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

517947

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.513

High

517963

LPD6B
Ly6/PLAUR domain-containing protein 6B

1

0

High-throughput

0.513

High

517967

CNPY3
Protein canopy homolog 3

1

0

High-throughput

0.513

High

517976

DJB11
DnaJ homolog subfamily B member 11

1

1

High-throughput

0.508

High

376363

PDGFA
Platelet-derived growth factor subunit A

1

9

Small-scale

0.501

High

394022

A4
Amyloid-beta precursor protein

1

8

Small-scale

0.501

High

419145

ITAV
Integrin alpha-V

1

5

Small-scale

0.501

High

517921

MAG
Myelin-associated glycoprotein

1

5

Small-scale

0.501

High

517923

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

3

Small-scale

0.501

High

517925

LYOX
Protein-lysine 6-oxidase

1

1

Small-scale

0.501

High

517936

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.493

High

269290

SG2A1
Mammaglobin-B

1

1

High-throughput

0.489

High

517954

IGFL1
Insulin growth factor-like family member 1

1

1

High-throughput

0.489

High

517956

IGFL3
Insulin growth factor-like family member 3

1

1

High-throughput

0.489

High

517964

OIT3
Oncoprotein-induced transcript 3 protein

1

5

High-throughput

0.489

High

517977

KLF15
Krueppel-like factor 15

1

2

High-throughput

0.489

High

517978

FBX2
F-box only protein 2

1

5

High-throughput

0.489

High

129672

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

5

High-throughput

0.479

High

204977

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

517914

PDIA4
Protein disulfide-isomerase A4

1

6

High-throughput

0.479

High

517926

PDIA3
Protein disulfide-isomerase A3

1

6

Small-scale

0.479

High

517927

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

517930

VHL
von Hippel-Lindau disease tumor suppressor

1

4

Small-scale

0.479

High

517934

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

517937

EFNA4
Ephrin-A4

1

1

High-throughput

0.479

High

517952

KLF17
Krueppel-like factor 17

1

3

High-throughput

0.470

High

517933

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.458

High

517943

CUL3
Cullin-3

1

0

High-throughput

0.458

High

517975

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

256848

SOCS5
Suppressor of cytokine signaling 5

1

1

Small-scale

0.437

High

517957

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

283669

CYTF
Cystatin-F

1

0

High-throughput

0.279

Low

517946

CART

1

0

High-throughput

0.279

Low

517965

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

0

High-throughput

0.279

Low

517972

TWSG1
Twisted gastrulation protein homolog 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024