Protein: P3H3
Prolyl 3-hydroxylase 3 (EC 1.14.11.7) (Leprecan-like protein 2) (Protein B)

Gene: P3H3
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q8IVL6

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005783 - endoplasmic reticulum
GO:0008285 - negative regulation of cell population proliferation
GO:0017185 - peptidyl-lysine hydroxylation
GO:0019797 - procollagen-proline 3-dioxygenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1104058

P3H1
Prolyl 3-hydroxylase 1

1

3

High-throughput

0.691

High

1069945

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

0

High-throughput

0.638

High

972779

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

1

High-throughput

0.628

High

1034483

OS9
Protein OS-9

2

1

High-throughput

0.628

High

345192

KNG1
Kininogen-1

3

5

High-throughput

0.609

High

362539

C1QB
Complement C1q subcomponent subunit B

3

20

High-throughput

0.609

High

473760

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

3

19

High-throughput

0.609

High

606905

IDS
Iduronate 2-sulfatase

3

2

High-throughput

0.609

High

815696

TNFL6
Tumor necrosis factor ligand superfamily member 6

3

1

High-throughput

0.609

High

1166150

OLFM4
Olfactomedin-4

3

1

High-throughput

0.609

High

1217663

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

20

High-throughput

0.609

High

1049258

KEAP1
Kelch-like ECH-associated protein 1

2

0

High-throughput

0.602

High

1217676

COLQ
Acetylcholinesterase collagenic tail peptide

2

9

High-throughput

0.574

High

1216343

KRA13
Keratin-associated protein 1-3

2

2

High-throughput

0.553

High

1217664

KRA92
Keratin-associated protein 9-2

2

2

High-throughput

0.553

High

328226

LGI1
Leucine-rich glioma-inactivated protein 1

1

2

High-throughput

0.536

High

378837

HRG
Histidine-rich glycoprotein

1

5

High-throughput

0.536

High

502297

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.536

High

1079670

ADIPO
Adiponectin

1

20

High-throughput

0.536

High

1217656

FIBIN
Fin bud initiation factor homolog

1

1

High-throughput

0.536

High

1217666

RTN4R
Reticulon-4 receptor

1

1

High-throughput

0.536

High

1217668

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.536

High

1217673

DNJB9
DnaJ homolog subfamily B member 9

1

4

High-throughput

0.536

High

609407

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.515

High

1217675

UBQL1
Ubiquilin-1

1

1

High-throughput

0.515

High

1217659

TRI63
E3 ubiquitin-protein ligase TRIM63

1

6

High-throughput

0.494

High

1217665

TRI55
Tripartite motif-containing protein 55

1

6

High-throughput

0.494

High

791738

HD
Huntingtin

1

0

High-throughput

0.493

High

70526

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

20

High-throughput

0.489

High

158953

NCTR3
Natural cytotoxicity triggering receptor 3

1

2

High-throughput

0.489

High

201528

DHH
Desert hedgehog protein

1

1

High-throughput

0.489

High

211380

PI15
Peptidase inhibitor 15

1

2

High-throughput

0.489

High

257276

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

2

High-throughput

0.489

High

362481

C1QA
Complement C1q subcomponent subunit A

1

17

High-throughput

0.489

High

389475

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

398554

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.489

High

474740

CFC1
Cryptic protein

1

1

High-throughput

0.489

High

533001

PRG2
Bone marrow proteoglycan

1

3

High-throughput

0.489

High

535659

EDN3
Endothelin-3

1

1

High-throughput

0.489

High

557187

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.489

High

610671

IBP4
Insulin-like growth factor-binding protein 4

1

1

High-throughput

0.489

High

875867

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.489

High

885649

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

2

High-throughput

0.489

High

892753

C1QT8
Complement C1q tumor necrosis factor-related protein 8

1

20

High-throughput

0.489

High

964669

IL5RA
Interleukin-5 receptor subunit alpha

1

1

High-throughput

0.489

High

1072538

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.489

High

1084522

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

6

High-throughput

0.489

High

1217655

SFPA2
Pulmonary surfactant-associated protein A2

1

10

High-throughput

0.489

High

1217658

GGH
Gamma-glutamyl hydrolase

1

1

High-throughput

0.489

High

1217662

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

20

High-throughput

0.489

High

1217667

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.489

High

1217669

EMIL3
EMILIN-3

1

3

High-throughput

0.489

High

1217670

CBLN4
Cerebellin-4

1

20

High-throughput

0.489

High

1217674

EPDR1
Mammalian ependymin-related protein 1

1

1

High-throughput

0.489

High

1217678

LIPG
Endothelial lipase

1

2

High-throughput

0.489

High

531895

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.479

High

1217660

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1217661

OPTN
Optineurin

1

1

High-throughput

0.470

High

358530

CO1A1
Collagen alpha-1(I) chain

1

2

Small-scale

0.445

High

125565

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.437

High

205630

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

319252

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.437

High

1170694

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1217671

T106B
Transmembrane protein 106B

1

3

High-throughput

0.437

High

976239

UPAR
Urokinase plasminogen activator surface receptor

3

0

High-throughput

0.347

High

1205529

TMM25
Transmembrane protein 25

3

0

High-throughput

0.347

High

504357

HSP7C
Heat shock cognate 71 kDa protein

2

0

High-throughput

0.328

High

539818

IDE
Insulin-degrading enzyme

2

0

High-throughput

0.328

High

1030827

SG2A2
Mammaglobin-A

2

0

High-throughput

0.328

High

1217677

INSL5
Insulin-like peptide INSL5

2

0

High-throughput

0.328

High

888581

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

1071255

K1H1
Keratin, type I cuticular Ha1

2

0

High-throughput

0.316

High

71174

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

0

High-throughput

0.279

Low

146684

SOCS7
Suppressor of cytokine signaling 7

1

0

High-throughput

0.279

Low

454096

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.279

Low

473602

DC8L2
DDB1- and CUL4-associated factor 8-like protein 2

1

0

High-throughput

0.279

Low

486286

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

614217

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.279

Low

685266

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

0

High-throughput

0.279

Low

851146

PRELP
Prolargin

1

0

High-throughput

0.279

Low

1044376

PTC1
Protein patched homolog 1

1

0

High-throughput

0.279

Low

1081793

PROL4
Proline-rich protein 4

1

0

High-throughput

0.279

Low

1115386

AKD1A
Ankyrin repeat and death domain-containing protein 1A

1

0

High-throughput

0.279

Low

1217657

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

1217672

SPMA2
Sperm microtubule associated protein 2

1

0

High-throughput

0.279

Low

1217680

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.279

Low

1191440

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

1217679

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1165294

KIRR2
Kin of IRRE-like protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024