Protein: PYR1
Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl-phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]

Gene: PYR1, Cad
Organism: Mus musculus
Interactions: 18
UniProt ID: B2RQC6

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0002134 - UTP binding
GO:0004070 - aspartate carbamoyltransferase activity
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

70560

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.536

High

70562

TNIK
Traf2 and NCK-interacting protein kinase

1

7

High-throughput

0.536

High

70565

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.536

High

70567

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

3

High-throughput

0.536

High

70569

MYOME
Myomegalin

1

2

High-throughput

0.536

High

70574

TSC1
Hamartin

1

3

High-throughput

0.536

High

70576

NPHP1
Nephrocystin-1

1

0

High-throughput

0.513

High

70564

PPP5
Serine/threonine-protein phosphatase 5

1

6

High-throughput

0.479

High

70568

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

70570

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

4

High-throughput

0.479

High

70572

FOXP3
Forkhead box protein P3

1

1

High-throughput

0.479

High

70573

RN138
E3 ubiquitin-protein ligase RNF138

1

1

Small-scale

0.479

High

70575

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.479

High

70566

TEDC2
Tubulin epsilon and delta complex protein 2

1

0

High-throughput

0.458

High

70559

MET
Hepatocyte growth factor receptor

1

5

High-throughput

0.445

High

70571

FTM
Protein fantom

1

2

High-throughput

0.445

High

70561

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.426

High

70563

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.426

High


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Last updated: 15 Jul 2024