Protein: HACD2
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B)

Gene: HACD2
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q6Y1H2

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0018812 - 3-hydroxyacyl-CoA dehydratase activity
GO:0019899 - enzyme binding
GO:0030148 - sphingolipid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1167869

TECR
Very-long-chain enoyl-CoA reductase

5

1

High-throughput

0.721

High

792797

EAA3
Excitatory amino acid transporter 3

2

1

High-throughput

0.628

High

847519

BAP31
B-cell receptor-associated protein 31

1

1

Small-scale

0.582

High

1167857

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.580

High

1167870

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

626538

FPR2
N-formyl peptide receptor 2

2

4

High-throughput

0.574

High

626744

NK1R
Substance-P receptor

2

2

High-throughput

0.574

High

686317

VIPR1
Vasoactive intestinal polypeptide receptor 1

2

3

High-throughput

0.574

High

723333

APJ
Apelin receptor

2

2

High-throughput

0.574

High

783660

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

3

High-throughput

0.574

High

1078095

AAAT
Neutral amino acid transporter B(0)

2

1

High-throughput

0.574

High

1083450

C3AR
C3a anaphylatoxin chemotactic receptor

2

4

High-throughput

0.574

High

1167850

SPP2B
Signal peptide peptidase-like 2B

2

1

High-throughput

0.574

High

1167864

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

2

1

High-throughput

0.574

High

369864

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

1167854

LPAR1
Lysophosphatidic acid receptor 1

2

3

High-throughput

0.558

High

163853

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.536

High

558746

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

1

High-throughput

0.536

High

867996

VMAT1
Chromaffin granule amine transporter

1

4

High-throughput

0.536

High

1167856

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

4

High-throughput

0.536

High

373031

VTNC
Vitronectin

1

0

High-throughput

0.513

High

1167859

BSCL2
Seipin

1

0

High-throughput

0.513

High

1167862

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

475937

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

126611

P2Y10
Putative P2Y purinoceptor 10

1

5

High-throughput

0.489

High

172069

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.489

High

781076

OPRX
Nociceptin receptor

1

2

High-throughput

0.489

High

795980

MAGA8
Melanoma-associated antigen 8

1

1

High-throughput

0.489

High

814266

GLR
Glucagon receptor

1

3

High-throughput

0.489

High

825064

PTH2R
Parathyroid hormone 2 receptor

1

3

High-throughput

0.489

High

877074

CASP6
Caspase-6

1

1

High-throughput

0.489

High

985353

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.489

High

1030977

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

4

High-throughput

0.489

High

1167863

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.489

High

1167865

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

1167867

AT133
Polyamine-transporting ATPase 13A3

1

5

High-throughput

0.489

High

386957

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

545457

RAC2
Ras-related C3 botulinum toxin substrate 2

1

8

High-throughput

0.479

High

892444

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.479

High

900609

RHOA
Transforming protein RhoA

1

10

High-throughput

0.479

High

1165695

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1167846

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

4

High-throughput

0.479

High

1167855

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

1044747

I10R1
Interleukin-10 receptor subunit alpha

1

1

High-throughput

0.470

High

529305

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

205563

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

1147607

FTM
Protein fantom

1

1

High-throughput

0.437

High

1156612

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

1167845

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1167852

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.437

High

1167860

TECT2
Tectonic-2

1

3

High-throughput

0.437

High

1167866

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1160127

S39A4
Zinc transporter ZIP4

3

0

High-throughput

0.347

High

206491

B4GA1
Beta-1,4-glucuronyltransferase 1

2

0

High-throughput

0.328

High

1167851

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

0

High-throughput

0.328

High

1167868

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

70814

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

1128626

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

270962

SPAG6
Sperm-associated antigen 6

1

0

High-throughput

0.279

Low

768545

ADCY8
Adenylate cyclase type 8

1

0

High-throughput

0.279

Low

814379

AL1A3
Retinaldehyde dehydrogenase 3

1

0

High-throughput

0.279

Low

825659

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.279

Low

1156852

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.279

Low

1167847

PB1
Protein polybromo-1

1

0

High-throughput

0.279

Low

1167848

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1167849

IT70B
Intraflagellar transport protein 70B

1

0

High-throughput

0.279

Low

1167853

SFT2A
Vesicle transport protein SFT2A

1

0

High-throughput

0.279

Low

1167858

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.279

Low

1167861

OPALI
Opalin

1

0

High-throughput

0.279

Low

214304

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

334220

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.249

Low

426839

ASGR2
Asialoglycoprotein receptor 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024