Protein: TBD2B
TBC1 domain family member 2B

Gene: TBD2B, TBC1D2B
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q9UPU7

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0006897 - endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1350164

PAK5
Serine/threonine-protein kinase PAK 5

2

14

High-throughput

0.811

High

914465

RB11A
Ras-related protein Rab-11A

2

20

High-throughput

0.754

High

234409

EVI5
Ecotropic viral integration site 5 protein homolog

1

11

High-throughput

0.691

High

885000

SNX16
Sorting nexin-16

1

3

High-throughput

0.691

High

573113

PRS6A
26S proteasome regulatory subunit 6A

3

10

High-throughput

0.667

High

1271910

APBB2
Amyloid beta precursor protein binding family B member 2

3

2

High-throughput

0.667

High

1328068

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

2

20

Small-scale

0.655

High

881121

CAV3
Caveolin-3

2

2

High-throughput

0.628

High

1290670

PTCD3
Small ribosomal subunit protein mS39

2

1

High-throughput

0.628

High

1033938

SNTB2
Beta-2-syntrophin

1

10

High-throughput

0.618

High

592584

RAB5A
Ras-related protein Rab-5A

1

20

High-throughput

0.618

High

852679

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

892684

RAC3
Ras-related C3 botulinum toxin substrate 3

1

19

High-throughput

0.618

High

916079

RHOB
Rho-related GTP-binding protein RhoB

1

19

High-throughput

0.618

High

921777

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

8

High-throughput

0.618

High

925738

RAC1
Ras-related C3 botulinum toxin substrate 1

1

19

High-throughput

0.618

High

951462

RHOG
Rho-related GTP-binding protein RhoG

1

17

High-throughput

0.618

High

1066883

KIF14
Kinesin-like protein KIF14

1

15

High-throughput

0.618

High

1070461

RAB35
Ras-related protein Rab-35

1

20

High-throughput

0.618

High

1146966

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.618

High

1269257

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1292301

AURKB
Aurora kinase B

1

10

High-throughput

0.618

High

1333813

ECT2
Protein ECT2

1

8

High-throughput

0.618

High

456369

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

0

High-throughput

0.602

High

217963

PRKY
Putative serine/threonine-protein kinase PRKY

1

9

High-throughput

0.575

High

1103177

KLH40
Kelch-like protein 40

2

2

High-throughput

0.574

High

1132273

CF141
Uncharacterized protein C6orf141

2

1

High-throughput

0.574

High

1357763

WASC3
WASH complex subunit 3

2

1

High-throughput

0.574

High

891360

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.569

High

1326217

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

20

High-throughput

0.569

High

1330673

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

20

Small-scale

0.561

High

592065

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.553

High

884617

RAB25
Ras-related protein Rab-25

1

20

High-throughput

0.553

High

149937

RFXK
DNA-binding protein RFXANK

1

5

High-throughput

0.536

High

277376

ST1C4
Sulfotransferase 1C4

1

1

High-throughput

0.536

High

335327

DYR
Dihydrofolate reductase

1

2

High-throughput

0.536

High

515971

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

5

High-throughput

0.536

High

1126955

EFMT2
EEF1A lysine methyltransferase 2

1

1

High-throughput

0.536

High

1284843

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

1311638

NAA11
N-alpha-acetyltransferase 11

1

2

High-throughput

0.536

High

1318426

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

1332133

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

1

High-throughput

0.536

High

1347551

ASB6
Ankyrin repeat and SOCS box protein 6

1

3

High-throughput

0.536

High

1356180

HSPB8
Heat shock protein beta-8

1

3

High-throughput

0.536

High

306356

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.527

High

1315814

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

20

High-throughput

0.527

High

1044277

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.514

High

597556

GSTM3
Glutathione S-transferase Mu 3

1

0

High-throughput

0.513

High

1253471

NT5C
5'(3')-deoxyribonucleotidase, cytosolic type

1

0

High-throughput

0.513

High

1260617

BRK1
Protein BRICK1

1

0

High-throughput

0.513

High

1297338

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

152838

TRDMT
tRNA

1

1

High-throughput

0.494

High

416730

S10A6
Protein S100-A6

1

0

High-throughput

0.493

High

71279

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

7

High-throughput

0.489

High

175512

RA51B
DNA repair protein RAD51 homolog 2

1

2

High-throughput

0.489

High

276289

CIB2
Calcium and integrin-binding family member 2

1

8

High-throughput

0.489

High

1100178

INF2
Inverted formin-2

1

6

High-throughput

0.489

High

1128385

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

1

High-throughput

0.489

High

1232987

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

2

High-throughput

0.489

High

1238092

CE120
Centrosomal protein of 120 kDa

1

15

High-throughput

0.489

High

1302193

TCPQM
T-complex protein 1 subunit theta-like 2

1

6

High-throughput

0.489

High

1306183

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.489

High

1334080

SYP2L
Synaptopodin 2-like protein

1

6

High-throughput

0.489

High

1357623

TFR2
Transferrin receptor protein 2

1

1

High-throughput

0.489

High

1357764

LOXL2
Lysyl oxidase homolog 2

1

1

High-throughput

0.489

High

163474

XPO1
Exportin-1

1

15

High-throughput

0.479

High

272764

OFD1
Centriole and centriolar satellite protein OFD1

1

12

High-throughput

0.479

High

302050

TRI37
E3 ubiquitin-protein ligase TRIM37

1

14

High-throughput

0.479

High

409279

K2C8
Keratin, type II cytoskeletal 8

1

3

High-throughput

0.479

High

430387

PROF1
Profilin-1

1

3

High-throughput

0.479

High

567333

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

840610

VASP
Vasodilator-stimulated phosphoprotein

1

3

High-throughput

0.479

High

1081175

CCDC6
Coiled-coil domain-containing protein 6

1

14

High-throughput

0.479

High

1267906

CNOT9
CCR4-NOT transcription complex subunit 9

1

1

High-throughput

0.479

High

1284674

VP33A
Vacuolar protein sorting-associated protein 33A

1

6

High-throughput

0.479

High

1302518

CEP89
Centrosomal protein of 89 kDa

1

11

High-throughput

0.479

High

1310221

LZTS2
Leucine zipper putative tumor suppressor 2

1

16

High-throughput

0.479

High

1244004

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1286564

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.458

High

1347891

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

776859

STAT3
Signal transducer and activator of transcription 3

1

4

High-throughput

0.445

High

832879

TSP3
Thrombospondin-3

1

2

High-throughput

0.437

High

1152196

LTOR1
Ragulator complex protein LAMTOR1

1

4

High-throughput

0.437

High

1159474

FBX42
F-box only protein 42

1

5

High-throughput

0.437

High

1347628

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

2

High-throughput

0.437

High

1091189

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

1

High-throughput

0.407

High

1349914

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

4

High-throughput

0.407

High

1357762

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.328

High

646007

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

1101796

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1224027

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

1297923

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024