Protein: LRSM1
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase) (hTAL)

Gene: LRSM1, LRSAM1
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q6UWE0

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006914 - autophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

896468

UBE2N
Ubiquitin-conjugating enzyme E2 N

3

5

Small-scale

0.862

High

849345

UB2D1
Ubiquitin-conjugating enzyme E2 D1

3

6

Small-scale

0.857

High

1165198

LRSM1
E3 ubiquitin-protein ligase LRSAM1

2

19

Small-scale

0.781

High

1165209

LRC46
Leucine-rich repeat-containing protein 46

3

20

High-throughput

0.770

High

1165212

TS101
Tumor susceptibility gene 101 protein

10

2

Small-scale

0.761

High

851826

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

6

High-throughput

0.698

High

895817

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

6

High-throughput

0.698

High

908715

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

10

High-throughput

0.698

High

919756

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

6

High-throughput

0.698

High

1165208

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

7

High-throughput

0.698

High

1165227

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

6

High-throughput

0.698

High

1165228

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

18

High-throughput

0.698

High

1165211

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

20

High-throughput

0.691

High

169292

MDM4
Protein Mdm4

1

0

High-throughput

0.663

High

1081077

CCDC6
Coiled-coil domain-containing protein 6

3

7

High-throughput

0.653

High

475933

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

High-throughput

0.647

High

896321

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

8

High-throughput

0.621

High

930268

UBC9
SUMO-conjugating enzyme UBC9

1

8

High-throughput

0.621

High

868556

ATX1
Ataxin-1

2

1

High-throughput

0.620

High

1049984

SCRIB
Protein scribble homolog

1

20

High-throughput

0.618

High

338580

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.618

High

1151542

XAF1
XIAP-associated factor 1

2

1

High-throughput

0.606

High

1165202

Q7KZS0
SUMO-conjugating enzyme UBC9

1

7

High-throughput

0.594

High

1165214

PHF23
PHD finger protein 23

2

0

Small-scale

0.593

High

1165218

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

1130228

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

19

High-throughput

0.575

High

869673

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.543

High

843747

FXR1
RNA-binding protein FXR1

1

5

High-throughput

0.541

High

883164

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

4

High-throughput

0.541

High

992352

KLC1
Kinesin light chain 1

1

2

High-throughput

0.541

High

1165200

RN111
E3 ubiquitin-protein ligase Arkadia

1

2

High-throughput

0.541

High

1165203

TRI74
Tripartite motif-containing protein 74

1

3

High-throughput

0.541

High

1165207

TSC1
Hamartin

1

9

High-throughput

0.541

High

1165216

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

1

High-throughput

0.541

High

1165226

NINL
Ninein-like protein

1

4

High-throughput

0.541

High

1165229

TRI17
E3 ubiquitin-protein ligase TRIM17

1

3

High-throughput

0.541

High

150066

TYB4Y
Thymosin beta-4, Y-chromosomal

1

1

High-throughput

0.536

High

849116

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

High-throughput

0.536

High

932999

ACTS
Actin, alpha skeletal muscle

1

7

High-throughput

0.536

High

1165199

MPRIP
Myosin phosphatase Rho-interacting protein

1

6

High-throughput

0.536

High

1165213

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

1

High-throughput

0.536

High

1165222

RAI14
Ankycorbin

1

9

High-throughput

0.536

High

72141

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

7

High-throughput

0.528

High

1023490

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

0

High-throughput

0.518

High

819095

LSS
Lanosterol synthase

1

0

High-throughput

0.513

High

1165215

PAPOG
Poly(A) polymerase gamma

1

0

High-throughput

0.513

High

1165204

UEVLD
Ubiquitin-conjugating enzyme E2 variant 3

1

2

High-throughput

0.494

High

1165221

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

1

High-throughput

0.489

High

173968

ATX7
Ataxin-7

1

0

High-throughput

0.486

High

271121

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

2

High-throughput

0.481

High

1165219

GP108
Protein GPR108

1

1

High-throughput

0.481

High

1165224

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

2

High-throughput

0.481

High

119981

AP3B1
AP-3 complex subunit beta-1

1

1

Small-scale

0.479

High

347107

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

349417

RASH
GTPase HRas

1

16

High-throughput

0.479

High

431973

HS90A
Heat shock protein HSP 90-alpha

1

5

High-throughput

0.479

High

438283

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

1030306

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

Small-scale

0.479

High

1041858

CUL3
Cullin-3

1

6

High-throughput

0.479

High

1165201

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1165220

KCNH7
Potassium voltage-gated channel subfamily H member 7

1

2

High-throughput

0.470

High

795639

MAGA1
Melanoma-associated antigen 1

1

0

Small-scale

0.460

High

1165206

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

501108

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

18

High-throughput

0.457

High

818878

RXRG
Retinoic acid receptor RXR-gamma

1

11

High-throughput

0.457

High

1165210

Q96I30
GPR108 protein

1

1

High-throughput

0.457

High

726890

FUS
RNA-binding protein FUS

1

1

Small-scale

0.445

High

1047129

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

891191

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.438

High

1165223

MUTYH
Adenine DNA glycosylase

1

0

High-throughput

0.438

High

1165225

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.438

High

441746

CFAH
Complement factor H

1

2

Small-scale

0.437

High

155913

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

1

High-throughput

0.417

High

421287

LIPF
Gastric triacylglycerol lipase

3

0

High-throughput

0.347

High

1165217

ZMAT4
Zinc finger matrin-type protein 4

2

0

High-throughput

0.316

High

1165205

F178B
Protein FAM178B

1

0

High-throughput

0.282

High

1081916

GRIK5
Glutamate receptor ionotropic, kainate 5

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024