Protein: RN125
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)

Gene: RN125, RNF125
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q96EQ8

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000209 - protein polyubiquitination
GO:0002039 - p53 binding
GO:0002250 - adaptive immune response
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849405

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.918

High

159082

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

3

20

Small-scale

0.858

High

1290194

RN125
E3 ubiquitin-protein ligase RNF125

3

18

Small-scale

0.840

High

895875

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.793

High

932558

UB2L3
Ubiquitin-conjugating enzyme E2 L3

2

20

High-throughput

0.791

High

896352

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

High-throughput

0.768

High

1290196

UB2E2
Ubiquitin-conjugating enzyme E2 E2

2

20

Small-scale

0.726

High

919821

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.698

High

1138902

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.698

High

1284871

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1290117

CHFR
E3 ubiquitin-protein ligase CHFR

1

16

High-throughput

0.698

High

1290204

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

896516

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.625

High

1290199

PCGF1
Polycomb group RING finger protein 1

1

18

High-throughput

0.625

High

321926

RIGI
Antiviral innate immune response receptor RIG-I

2

20

Small-scale

0.611

High

1290203

PD1L1
Programmed cell death 1 ligand 1

2

11

Small-scale

0.584

High

476188

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

Small-scale

0.579

High

387282

P53
Cellular tumor antigen p53

1

10

Small-scale

0.561

High

1049115

TRI14
Tripartite motif-containing protein 14

1

19

Small-scale

0.561

High

668901

PML
Protein PML

1

20

High-throughput

0.541

High

1190457

TRI46
Tripartite motif-containing protein 46

1

20

High-throughput

0.541

High

616850

JAK1
Tyrosine-protein kinase JAK1

2

20

Small-scale

0.533

High

72151

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

338828

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

585033

RO52
E3 ubiquitin-protein ligase TRIM21

1

18

Small-scale

0.479

High

1052284

SRC8
Src substrate cortactin

1

12

Small-scale

0.479

High

1290197

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

16

Small-scale

0.479

High

1290201

IFIH1
Interferon-induced helicase C domain-containing protein 1

1

20

Small-scale

0.479

High

271168

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

20

High-throughput

0.439

High

1128480

EFHC1
EF-hand domain-containing protein 1

1

2

High-throughput

0.439

High

1186229

BHA09
Class A basic helix-loop-helix protein 9

1

4

High-throughput

0.439

High

1254731

MYOZ3
Myozenin-3

1

1

High-throughput

0.439

High

1290195

ZN414
Zinc finger protein 414

1

1

High-throughput

0.439

High

1290200

FND11
Fibronectin type III domain-containing protein 11

1

1

High-throughput

0.439

High

134162

DDX3X
ATP-dependent RNA helicase DDX3X

1

8

Small-scale

0.437

High

724960

MYH9
Myosin-9

1

7

Small-scale

0.437

High

891966

ACTB
Actin, cytoplasmic 1

1

13

Small-scale

0.437

High

1030414

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

Small-scale

0.437

High

1190056

MAVS
Mitochondrial antiviral-signaling protein

1

20

Small-scale

0.437

High

1290202

ILRL2
Interleukin-1 receptor-like 2

1

13

Small-scale

0.437

High

1290198

SPAG8
Sperm-associated antigen 8

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024