Protein: BIRC8
Baculoviral IAP repeat-containing protein 8 (Inhibitor of apoptosis-like protein 2) (IAP-like protein 2) (ILP-2) (Testis-specific inhibitor of apoptosis)

Gene: BIRC8
Organism: Homo sapiens
Interactions: 33
UniProt ID: Q96P09

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0031398 - positive regulation of protein ubiquitination
GO:0043027 - cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

876998

CASP9
Caspase-9

5

20

Small-scale

0.925

High

1298966

DBLOH
Diablo IAP-binding mitochondrial protein

4

11

Small-scale

0.892

High

957767

XIAP
E3 ubiquitin-protein ligase XIAP

3

15

High-throughput

0.861

High

849413

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

High-throughput

0.698

High

851874

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

High-throughput

0.698

High

895884

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

High-throughput

0.698

High

896521

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.698

High

919831

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

High-throughput

0.698

High

1033135

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.698

High

1284875

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

High-throughput

0.698

High

1298970

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

412312

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.691

High

204028

HTRA2
Serine protease HTRA2, mitochondrial

3

15

High-throughput

0.667

High

335165

DHE3
Glutamate dehydrogenase 1, mitochondrial

3

1

High-throughput

0.667

High

896357

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

20

High-throughput

0.621

High

1298965

CDK19
Cyclin-dependent kinase 19

2

9

High-throughput

0.611

High

891428

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

20

High-throughput

0.555

High

224832

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

4

High-throughput

0.536

High

1268328

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

6

High-throughput

0.536

High

1298968

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.536

High

1298969

LIMC1
LIM and calponin homology domains-containing protein 1

1

4

High-throughput

0.536

High

72153

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

1298964

RIOK2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

1298967

MTMR4
Myotubularin-related protein 4

1

0

High-throughput

0.513

High

657539

TMOD1
Tropomodulin-1

1

6

High-throughput

0.489

High

1071145

RBP1
RalA-binding protein 1

1

6

High-throughput

0.489

High

1203009

LIPB1
Liprin-beta-1

1

4

High-throughput

0.489

High

155625

TNPO2
Transportin-2

1

8

High-throughput

0.481

High

1298971

MAGD1
Melanoma-associated antigen D1

1

6

High-throughput

0.481

High

329185

F107A
Actin-associated protein FAM107A

1

0

Small-scale

0.460

High

73038

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

8

High-throughput

0.445

High

1115343

PKHN1
Pleckstrin homology domain-containing family N member 1

1

1

Small-scale

0.437

High

1174415

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024