Protein: TRIM2
Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2)

Gene: TRIM2
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9C040

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0017148 - negative regulation of translation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

262194

TRIM3
Tripartite motif-containing protein 3

5

17

Small-scale

0.924

High

849440

UB2D1
Ubiquitin-conjugating enzyme E2 D1

3

20

Small-scale

0.868

High

851883

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

20

Small-scale

0.800

High

895906

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.800

High

919854

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.800

High

1284885

UBE2W
Ubiquitin-conjugating enzyme E2 W

2

20

Small-scale

0.800

High

1297367

UB2E2
Ubiquitin-conjugating enzyme E2 E2

2

20

Small-scale

0.800

High

1318738

UB2D4
Ubiquitin-conjugating enzyme E2 D4

2

20

Small-scale

0.800

High

896371

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

High-throughput

0.783

High

909087

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

1138921

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.698

High

1282345

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

High-throughput

0.698

High

1318346

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

19

High-throughput

0.698

High

1155915

LRC8E
Volume-regulated anion channel subunit LRRC8E

4

4

High-throughput

0.697

High

1318735

TRIM2
Tripartite motif-containing protein 2

1

16

Small-scale

0.692

High

135951

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

896539

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.647

High

908268

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

20

Small-scale

0.647

High

1311510

UBAC1
Ubiquitin-associated domain-containing protein 1

4

9

High-throughput

0.642

High

1171604

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1300179

CIB3
Calcium and integrin-binding family member 3

3

4

High-throughput

0.616

High

1297986

KCTD7
BTB/POZ domain-containing protein KCTD7

2

9

High-throughput

0.606

High

941705

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

3

7

High-throughput

0.599

High

1318737

TNIK
TRAF2 and NCK-interacting protein kinase

2

11

High-throughput

0.590

High

1281716

UBE2F
NEDD8-conjugating enzyme UBE2F

1

20

Small-scale

0.579

High

851283

MAT1
CDK-activating kinase assembly factor MAT1

1

4

High-throughput

0.541

High

1224573

CDK20
Cyclin-dependent kinase 20

1

7

High-throughput

0.541

High

497564

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.536

High

1299554

KLHL5
Kelch-like protein 5

1

5

High-throughput

0.536

High

72162

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

794118

MATR3
Matrin-3

1

9

High-throughput

0.515

High

312738

CXB5
Gap junction beta-5 protein

1

6

High-throughput

0.494

High

599728

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

10

High-throughput

0.481

High

830470

KC1E
Casein kinase I isoform epsilon

1

5

High-throughput

0.481

High

1290398

DTBP1
Dysbindin

1

4

High-throughput

0.481

High

326773

SNAI1
Zinc finger protein SNAI1

1

20

Small-scale

0.479

High

387458

P53
Cellular tumor antigen p53

1

16

Small-scale

0.479

High

432239

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

438503

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

1042484

CUL3
Cullin-3

1

16

High-throughput

0.479

High

477745

HMN1
Humanin-like 1

1

0

Small-scale

0.458

High

206769

B2L11
Bcl-2-like protein 11

1

2

Small-scale

0.457

High

989105

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.457

High

1044130

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.445

High

1288094

OTUB2
Ubiquitin thioesterase OTUB2

1

11

High-throughput

0.439

High

101155

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

1202259

LCA5
Lebercilin

1

17

High-throughput

0.437

High

378158

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1318736

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.347

High

1294973

COG3
Conserved oligomeric Golgi complex subunit 3

2

0

High-throughput

0.316

High

260097

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024