Protein: SDC4
Syndecan-4 (SYND4) (Amphiglycan) (Ryudocan core protein)

Gene: SDC4
Organism: Homo sapiens
Interactions: 82
UniProt ID: P31431

Gene Ontology (top 5):
GO:0001657 - ureteric bud development
GO:0001843 - neural tube closure
GO:0001968 - fibronectin binding
GO:0005080 - protein kinase C binding
GO:0005796 - Golgi lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

680346

SDC2
Syndecan-2

2

15

Small-scale

0.799

High

680344

SDC4
Syndecan-4

1

10

Small-scale

0.680

High

399136

FGF1
Fibroblast growth factor 1

3

8

High-throughput

0.667

High

447027

FGF2
Fibroblast growth factor 2

3

8

Small-scale

0.656

High

182094

PDPK1
3-phosphoinositide-dependent protein kinase 1

3

2

High-throughput

0.650

High

253692

SDC3
Syndecan-3

1

15

Small-scale

0.647

High

680345

GP183
G-protein coupled receptor 183

2

1

High-throughput

0.628

High

213489

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

3

1

High-throughput

0.616

High

475388

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

3

High-throughput

0.602

High

562522

IL7RA
Interleukin-7 receptor subunit alpha

2

0

High-throughput

0.580

High

680353

PMP22
Peripheral myelin protein 22

2

0

High-throughput

0.580

High

369063

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

680380

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.553

High

469954

H2AZ
Histone H2A.Z

1

2

High-throughput

0.536

High

601469

FGFR2
Fibroblast growth factor receptor 2

1

4

High-throughput

0.536

High

609186

FGFR3
Fibroblast growth factor receptor 3

1

4

High-throughput

0.536

High

664351

AA2BR
Adenosine receptor A2b

1

1

High-throughput

0.536

High

680370

SULF2
Extracellular sulfatase Sulf-2

1

2

High-throughput

0.536

High

680373

CAMKV
CaM kinase-like vesicle-associated protein

1

2

High-throughput

0.536

High

680374

VANG1
Vang-like protein 1

1

4

High-throughput

0.536

High

680394

VANG2
Vang-like protein 2

1

4

High-throughput

0.536

High

495650

TGFB3
Transforming growth factor beta-3 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.518

High

680354

TGBR3
Transforming growth factor beta receptor type 3

1

0

High-throughput

0.513

High

680366

CARL1
F-actin-uncapping protein LRRC16A

1

0

High-throughput

0.513

High

680376

KRT35
Keratin, type I cuticular Ha5

1

0

High-throughput

0.513

High

680381

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.513

High

132751

SDCB1
Syntenin-1

1

4

Small-scale

0.501

High

394192

A4
Amyloid-beta precursor protein

1

1

Small-scale

0.501

High

566301

KPCA
Protein kinase C alpha type

1

4

Small-scale

0.501

High

680351

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.501

High

680358

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

2

Small-scale

0.501

High

680395

ALK
ALK tyrosine kinase receptor

1

5

High-throughput

0.500

High

158157

GIPC1
PDZ domain-containing protein GIPC1

1

0

Small-scale

0.493

High

441812

FGF4
Fibroblast growth factor 4

1

8

High-throughput

0.489

High

485203

TZAP
Telomere zinc finger-associated protein

1

2

High-throughput

0.489

High

680348

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

680349

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

High-throughput

0.489

High

680352

AMPD2
AMP deaminase 2

1

2

High-throughput

0.489

High

680355

ZNF92
Zinc finger protein 92

1

1

High-throughput

0.489

High

680357

TF3C1
General transcription factor 3C polypeptide 1

1

1

High-throughput

0.489

High

680360

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

2

High-throughput

0.489

High

680371

TM192
Transmembrane protein 192

1

1

High-throughput

0.489

High

680375

TF3C2
General transcription factor 3C polypeptide 2

1

1

High-throughput

0.489

High

680378

TM186
Transmembrane protein 186

1

1

High-throughput

0.489

High

680386

PRD10
PR domain zinc finger protein 10

1

4

High-throughput

0.489

High

680389

EVA1B
Protein eva-1 homolog B

1

1

High-throughput

0.489

High

680390

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.489

High

680391

PARP2
Poly [ADP-ribose] polymerase 2

1

2

High-throughput

0.489

High

680392

GMEB2
Glucocorticoid modulatory element-binding protein 2

1

5

High-throughput

0.489

High

680396

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

2

High-throughput

0.489

High

680397

GMEB1
Glucocorticoid modulatory element-binding protein 1

1

5

High-throughput

0.489

High

680363

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

0

Small-scale

0.480

High

680361

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

680369

TAXB1
Tax1-binding protein 1

1

3

High-throughput

0.479

High

680372

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

680382

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

680385

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.458

High

253777

XYLK
Glycosaminoglycan xylosylkinase

1

1

Small-scale

0.457

High

680347

MERL
Merlin

1

5

High-throughput

0.445

High

517086

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

72377

B3KW44
tRNA N(3)-methylcytidine methyltransferase

1

3

High-throughput

0.437

High

346041

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

528243

CCL5
C-C motif chemokine 5

1

1

Small-scale

0.437

High

680359

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

3

High-throughput

0.437

High

680367

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.437

High

680379

OPTN
Optineurin

1

1

High-throughput

0.437

High

680383

Q9H4D1
Protein kinase

1

3

High-throughput

0.437

High

528633

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

680350

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.407

High

680365

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.407

High

680384

METL8
tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial

1

3

High-throughput

0.407

High

596870

MAL
Myelin and lymphocyte protein

2

0

High-throughput

0.316

High

680393

PLAT4
Phospholipase A and acyltransferase 4

1

0

Small-scale

0.288

High

680377

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.282

High

680356

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.279

Low

680364

DREB
Drebrin

1

0

High-throughput

0.279

Low

680388

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

0

High-throughput

0.279

Low

150676

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

0

Small-scale

0.249

Low

680362

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.249

Low

680368

GP179
Probable G-protein coupled receptor 179

1

0

Small-scale

0.249

Low

680387

ANLN
Anillin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024