Protein: PAR6A
Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40)

Gene: PAR6A, PARD6A
Organism: Homo sapiens
Interactions: 67
UniProt ID: Q9NPB6

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0001933 - negative regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

784096

KPCI
Protein kinase C iota type

13

20

Small-scale

0.986

High

983925

KPCZ
Protein kinase C zeta type

12

20

Small-scale

0.982

High

1256901

PARD3
Partitioning defective 3 homolog

6

20

Small-scale

0.946

High

894470

CDC42
Cell division control protein 42 homolog

5

20

Small-scale

0.935

High

925642

RAC1
Ras-related C3 botulinum toxin substrate 1

2

20

Small-scale

0.831

High

924884

GRB2
Growth factor receptor-bound protein 2

2

14

High-throughput

0.819

High

1316970

PAR6B
Partitioning defective 6 homolog beta

2

15

High-throughput

0.811

High

1158580

L2GL2
LLGL scribble cell polarity complex component 2

4

8

High-throughput

0.702

High

872581

EPHB4
Ephrin type-B receptor 4

1

9

High-throughput

0.691

High

1043759

ASPP2
Apoptosis-stimulating of p53 protein 2

1

5

High-throughput

0.691

High

1304602

PI3R4
Phosphoinositide 3-kinase regulatory subunit 4

1

11

High-throughput

0.691

High

1342595

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

3

High-throughput

0.691

High

1026834

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

8

Small-scale

0.637

High

1267444

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

12

High-throughput

0.634

High

1071578

L2GL1
Lethal(2) giant larvae protein homolog 1

2

8

High-throughput

0.628

High

564698

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

Small-scale

0.621

High

151211

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

Small-scale

0.618

High

566485

KPCA
Protein kinase C alpha type

1

20

Small-scale

0.618

High

738580

TGFR1
TGF-beta receptor type-1

1

4

Small-scale

0.618

High

1183131

MARK2
Serine/threonine-protein kinase MARK2

1

10

High-throughput

0.618

High

1232504

PALS1
Protein PALS1

1

19

Small-scale

0.618

High

1246438

INADL
InaD-like protein

1

20

Small-scale

0.618

High

1296788

MARK4
MAP/microtubule affinity-regulating kinase 4

1

9

High-throughput

0.618

High

1336085

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

11

Small-scale

0.584

High

99493

F5GZI3
Par-3 family cell polarity regulator

1

20

High-throughput

0.575

High

1333743

ECT2
Protein ECT2

1

12

Small-scale

0.573

High

1087937

PTN21
Tyrosine-protein phosphatase non-receptor type 21

2

20

High-throughput

0.553

High

671027

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

5

High-throughput

0.536

High

850503

PLXA3
Plexin-A3

1

10

High-throughput

0.536

High

865087

TTC3
E3 ubiquitin-protein ligase TTC3

1

9

High-throughput

0.536

High

982528

1433F
14-3-3 protein eta

1

19

High-throughput

0.536

High

1198542

DPP9
Dipeptidyl peptidase 9

1

1

High-throughput

0.536

High

1294477

LRCH3
DISP complex protein LRCH3

1

8

High-throughput

0.536

High

1332497

RPAP3
RNA polymerase II-associated protein 3

1

7

High-throughput

0.536

High

1342591

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

1

High-throughput

0.536

High

1342596

SGT1
Protein SGT1 homolog

1

8

High-throughput

0.536

High

702802

CADH5
Cadherin-5

1

3

Small-scale

0.534

High

869891

PMS2
Mismatch repair endonuclease PMS2

1

0

High-throughput

0.513

High

1033441

ORC2
Origin recognition complex subunit 2

1

0

High-throughput

0.513

High

1060155

ARI5B
AT-rich interactive domain-containing protein 5B

1

0

High-throughput

0.513

High

1327186

T126A
Transmembrane protein 126A

1

0

High-throughput

0.513

High

1334473

ELP3
Elongator complex protein 3

1

0

High-throughput

0.513

High

1342594

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.513

High

1310807

WDR83
WD repeat domain-containing protein 83

1

2

Small-scale

0.504

High

395836

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

792010

HD
Huntingtin

1

4

Small-scale

0.500

High

968281

PLCB3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3

1

0

Small-scale

0.493

High

231727

KIF1B
Kinesin-like protein KIF1B

1

13

High-throughput

0.489

High

335199

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.489

High

1245848

RASF8
Ras association domain-containing protein 8

1

4

High-throughput

0.489

High

772172

VHL
von Hippel-Lindau disease tumor suppressor

1

1

Small-scale

0.479

High

847084

SMCA4
Transcription activator BRG1

1

2

High-throughput

0.479

High

909166

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

927560

1433Z
14-3-3 protein zeta/delta

1

19

High-throughput

0.479

High

1040015

DGKZ
Diacylglycerol kinase zeta

1

10

Small-scale

0.479

High

1148387

RHG17
Rho GTPase-activating protein 17

1

5

Small-scale

0.479

High

1163871

RICTR
Rapamycin-insensitive companion of mTOR

1

1

Small-scale

0.479

High

1236516

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

High-throughput

0.479

High

1334873

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

11

Small-scale

0.479

High

1342592

RN146
E3 ubiquitin-protein ligase RNF146

1

3

Small-scale

0.479

High

1140911

FBX31
F-box only protein 31

1

0

Small-scale

0.458

High

72472

B4DDV3
protein acetyllysine N-acetyltransferase

1

4

High-throughput

0.445

High

1242313

PNMA1
Paraneoplastic antigen Ma1

1

5

High-throughput

0.437

High

1335272

Q9HBD4
SMARCA4 isoform 2

1

2

High-throughput

0.407

High

1176184

NOL8
Nucleolar protein 8

1

0

High-throughput

0.279

Low

1298304

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.279

Low

1342593

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024