Protein: PMS2
Mismatch repair endonuclease PMS2 (EC 3.1.-.-) (DNA mismatch repair protein PMS2) (PMS1 protein homolog 2)

Gene: PMS2
Organism: Homo sapiens
Interactions: 79
UniProt ID: P54278

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0004519 - endonuclease activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

776278

MLH1
DNA mismatch repair protein Mlh1

30

13

Small-scale

0.993

High

794220

MSH2
DNA mismatch repair protein Msh2

3

20

Small-scale

0.827

High

855442

MSH6
DNA mismatch repair protein Msh6

3

20

Small-scale

0.827

High

869902

FAN1
Fanconi-associated nuclease 1

7

6

Small-scale

0.743

High

869885

FANCJ
Fanconi anemia group J protein

6

2

Small-scale

0.735

High

517150

PCNA
Proliferating cell nuclear antigen

3

5

Small-scale

0.651

High

594176

MSH3
DNA mismatch repair protein Msh3

1

20

High-throughput

0.618

High

475522

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

2

High-throughput

0.595

High

175847

P73
Tumor protein p73

2

2

Small-scale

0.594

High

226963

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

749279

BRCA1
Breast cancer type 1 susceptibility protein

2

3

High-throughput

0.584

High

869899

EXO1
Exonuclease 1

2

5

Small-scale

0.584

High

596382

RASA1
Ras GTPase-activating protein 1

1

1

High-throughput

0.541

High

612471

XPA
DNA repair protein complementing XP-A cells

1

2

High-throughput

0.541

High

681756

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.541

High

869863

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

3

High-throughput

0.541

High

869867

FANCC
Fanconi anemia group C protein

1

1

High-throughput

0.541

High

869874

SFRP4
Secreted frizzled-related protein 4

1

1

High-throughput

0.541

High

869880

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

High-throughput

0.541

High

207035

XRCC3
DNA repair protein XRCC3

1

3

High-throughput

0.536

High

161195

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.518

High

275726

ZN189
Zinc finger protein 189

1

0

High-throughput

0.518

High

869875

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

412102

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.513

High

869876

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.513

High

869887

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

869891

PAR6A
Partitioning defective 6 homolog alpha

1

0

High-throughput

0.513

High

869896

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

0

High-throughput

0.513

High

869873

FSCN1
Fascin

1

2

Small-scale

0.505

High

869878

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

2

High-throughput

0.494

High

869884

TRMO
tRNA

1

1

High-throughput

0.494

High

418074

NPM
Nucleophosmin

1

0

High-throughput

0.493

High

837880

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

358736

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.480

High

128831

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

3

High-throughput

0.479

High

162543

XPO1
Exportin-1

1

5

High-throughput

0.479

High

304091

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

High-throughput

0.479

High

325105

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

3

High-throughput

0.479

High

386376

P53
Cellular tumor antigen p53

1

2

High-throughput

0.479

High

572904

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

627221

MCM3
DNA replication licensing factor MCM3

1

2

High-throughput

0.479

High

668543

PML
Protein PML

1

6

High-throughput

0.479

High

722082

RFC2
Replication factor C subunit 2

1

2

High-throughput

0.479

High

730222

PRS7
26S proteasome regulatory subunit 7

1

1

High-throughput

0.479

High

847781

BRCA2
Breast cancer type 2 susceptibility protein

1

1

High-throughput

0.479

High

853215

IMA1
Importin subunit alpha-1

1

3

High-throughput

0.479

High

863181

COPB
Coatomer subunit beta

1

4

High-throughput

0.479

High

869861

PRS4
26S proteasome regulatory subunit 4

1

2

High-throughput

0.479

High

869862

PRS10
26S proteasome regulatory subunit 10B

1

3

High-throughput

0.479

High

869865

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

3

High-throughput

0.479

High

869866

PRKDC
DNA-dependent protein kinase catalytic subunit

1

4

High-throughput

0.479

High

869868

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

1

2

High-throughput

0.479

High

869870

IMB1
Importin subunit beta-1

1

2

High-throughput

0.479

High

869882

MMS19
MMS19 nucleotide excision repair protein homolog

1

3

High-throughput

0.479

High

869886

FACD2
Fanconi anemia group D2 protein

1

1

Small-scale

0.479

High

869888

SPRTN
DNA-dependent metalloprotease SPRTN

1

1

Small-scale

0.479

High

869892

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

869893

FANCI
Fanconi anemia group I protein

1

1

Small-scale

0.479

High

869894

ATD3A
ATPase family AAA domain-containing protein 3A

1

3

High-throughput

0.479

High

869898

COPG2
Coatomer subunit gamma-2

1

3

High-throughput

0.479

High

869900

RUVB2
RuvB-like 2

1

3

High-throughput

0.479

High

869901

RUVB1
RuvB-like 1

1

3

High-throughput

0.479

High

869903

COPG1
Coatomer subunit gamma-1

1

3

High-throughput

0.479

High

846906

SMCA4
Transcription activator BRG1

1

0

High-throughput

0.458

High

869864

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

869871

PSMD5
26S proteasome non-ATPase regulatory subunit 5

1

0

High-throughput

0.458

High

869872

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.458

High

869879

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

Small-scale

0.458

High

869890

CLSPN
Claspin

1

0

Small-scale

0.458

High

110648

H3BQ24
Fanconi-associated nuclease

1

6

High-throughput

0.445

High

73224

B4DZK1
cDNA FLJ50036, weakly similar to Myosin-11

1

5

High-throughput

0.439

High

869869

TRI29
Tripartite motif-containing protein 29

1

1

Small-scale

0.437

High

869877

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

869883

PSD2
PH and SEC7 domain-containing protein 2

1

3

High-throughput

0.437

High

869889

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

869895

PSD3
PH and SEC7 domain-containing protein 3

1

3

High-throughput

0.437

High

869897

CC180
Coiled-coil domain-containing protein 180

1

5

High-throughput

0.417

High

869881

FRMD6
FERM domain-containing protein 6

1

3

High-throughput

0.407

High

100621

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024