Protein: WASL
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)

Gene: WASL
Organism: Homo sapiens
Interactions: 100
UniProt ID: O00401

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

126883

WIPF1
WAS/WASL-interacting protein family member 1

8

16

Small-scale

0.978

High

126927

CDC42
Cell division control protein 42 homolog

7

20

Small-scale

0.959

High

126947

WIPF2
WAS/WASL-interacting protein family member 2

6

11

High-throughput

0.954

High

62637

WIPF3
WAS/WASL-interacting protein family member 3

4

12

High-throughput

0.911

High

126960

RHOJ
Rho-related GTP-binding protein RhoJ

4

20

High-throughput

0.903

High

126931

ACTG
Actin, cytoplasmic 2

2

8

Small-scale

0.819

High

126926

ACTB
Actin, cytoplasmic 1

2

8

High-throughput

0.789

High

126930

GRB2
Growth factor receptor-bound protein 2

10

20

Small-scale

0.759

High

126892

PAK4
Serine/threonine-protein kinase PAK 4

1

1

High-throughput

0.747

High

126909

NCK1
SH2/SH3 adapter protein NCK1

6

20

Small-scale

0.735

High

126928

ARP3
Actin-related protein 3

2

12

Small-scale

0.727

High

126929

ARP2
Actin-related protein 2

2

11

Small-scale

0.727

High

126885

NCK2
Cytoplasmic protein NCK2

5

20

High-throughput

0.727

High

126888

RNF8
E3 ubiquitin-protein ligase RNF8

5

5

High-throughput

0.720

High

126937

ACTBL
Beta-actin-like protein 2

1

8

High-throughput

0.691

High

126935

CIP4
Cdc42-interacting protein 4

4

20

Small-scale

0.687

High

126910

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

Small-scale

0.680

High

126902

PROF1
Profilin-1

3

5

Small-scale

0.676

High

126879

SDCB1
Syntenin-1

3

3

High-throughput

0.675

High

126882

ARPC3
Actin-related protein 2/3 complex subunit 3

3

4

High-throughput

0.675

High

126932

ACTC
Actin, alpha cardiac muscle 1

1

5

High-throughput

0.665

High

126943

RHG12
Rho GTPase-activating protein 12

3

4

High-throughput

0.665

High

126968

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

3

20

Small-scale

0.658

High

126969

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

3

20

Small-scale

0.658

High

126893

EGFR
Epidermal growth factor receptor

3

17

High-throughput

0.653

High

126899

CHLE
Cholinesterase

2

1

High-throughput

0.628

High

126936

ITSN1
Intersectin-1

2

20

Small-scale

0.628

High

126934

SRC8
Src substrate cortactin

2

20

Small-scale

0.624

High

126895

RASN
GTPase NRas

1

12

High-throughput

0.618

High

126955

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

126970

BAIP2
BAR/IMD domain-containing adapter protein 2

2

20

High-throughput

0.614

High

126880

ARC1B
Actin-related protein 2/3 complex subunit 1B

2

12

Small-scale

0.611

High

126939

DNMBP
Dynamin-binding protein

2

20

Small-scale

0.611

High

126890

SRBS2
Sorbin and SH3 domain-containing protein 2

2

20

High-throughput

0.606

High

126923

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

20

High-throughput

0.606

High

126925

ARPC4
Actin-related protein 2/3 complex subunit 4

2

3

High-throughput

0.606

High

126946

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

2

20

High-throughput

0.606

High

126963

ABI2
Abl interactor 2

2

20

High-throughput

0.606

High

126952

ATG4C
Cysteine protease ATG4C

2

0

High-throughput

0.602

High

126886

VINEX
Vinexin

2

20

Small-scale

0.601

High

126958

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

2

20

Small-scale

0.595

High

120747

APBB1
Amyloid beta precursor protein binding family B member 1

2

1

High-throughput

0.585

High

126933

PTK6
Protein-tyrosine kinase 6

1

20

High-throughput

0.573

High

126898

LCK
Tyrosine-protein kinase Lck

1

20

Small-scale

0.569

High

126957

CIB1
Calcium and integrin-binding protein 1

1

0

Small-scale

0.561

High

126924

CORO7
Coronin-7

1

8

Small-scale

0.561

High

126971

SNX9
Sorting nexin-9

1

16

Small-scale

0.561

High

126916

TNNT3
Troponin T, fast skeletal muscle

1

1

High-throughput

0.541

High

126954

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

9

High-throughput

0.541

High

126959

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

9

High-throughput

0.541

High

126901

PDIA1
Protein disulfide-isomerase

1

4

High-throughput

0.536

High

126962

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

12

High-throughput

0.536

High

126922

DSCR6
Protein ripply3

1

0

High-throughput

0.518

High

126917

ACY2
Aspartoacylase

1

0

High-throughput

0.513

High

126951

SKA1
Spindle and kinetochore-associated protein 1

1

0

High-throughput

0.513

High

126878

BIN1
Myc box-dependent-interacting protein 1

1

20

Small-scale

0.501

High

126884

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

20

Small-scale

0.501

High

126887

PR40A
Pre-mRNA-processing factor 40 homolog A

1

19

High-throughput

0.501

High

126897

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

126903

HS90A
Heat shock protein HSP 90-alpha

1

10

Small-scale

0.501

High

126904

HS90B
Heat shock protein HSP 90-beta

1

10

Small-scale

0.501

High

126905

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.501

High

126912

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

9

Small-scale

0.501

High

126938

FBP1L
Formin-binding protein 1-like

1

20

Small-scale

0.501

High

126956

FNBP1
Formin-binding protein 1

1

20

Small-scale

0.501

High

126967

ITBP2
Integrin beta-1-binding protein 2

1

2

High-throughput

0.494

High

126877

IPO5
Importin-5

1

3

High-throughput

0.481

High

126889

FCSD2
F-BAR and double SH3 domains protein 2

1

20

High-throughput

0.481

High

126894

HPT
Haptoglobin

1

2

High-throughput

0.481

High

126921

ANM2
Protein arginine N-methyltransferase 2

1

2

High-throughput

0.481

High

126942

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

High-throughput

0.481

High

126965

ITSN2
Intersectin-2

1

16

High-throughput

0.481

High

126914

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

Small-scale

0.480

High

126881

ARPC2
Actin-related protein 2/3 complex subunit 2

1

5

Small-scale

0.479

High

126891

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

7

High-throughput

0.479

High

126896

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

126907

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

126911

ITA2
Integrin alpha-2

1

5

Small-scale

0.479

High

126915

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

126918

CRK
Adapter molecule crk

1

20

Small-scale

0.479

High

126919

YAP1
Transcriptional coactivator YAP1

1

16

High-throughput

0.479

High

126920

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

9

High-throughput

0.479

High

126940

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.479

High

126941

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

126944

BICD2
Protein bicaudal D homolog 2

1

13

High-throughput

0.479

High

126950

SH3K1
SH3 domain-containing kinase-binding protein 1

1

20

High-throughput

0.479

High

126953

BICD1
Protein bicaudal D homolog 1

1

10

High-throughput

0.479

High

126964

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

126966

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

126972

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

2

High-throughput

0.479

High

126961

ZN395
Zinc finger protein 395

1

0

High-throughput

0.460

High

126913

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.458

High

91473

E7ERP6
NCK adaptor protein 2

1

20

High-throughput

0.457

High

126948

ROBO4
Roundabout homolog 4

1

8

Small-scale

0.457

High

126908

CD44
CD44 antigen

1

2

Small-scale

0.445

High

126949

OSTF1
Osteoclast-stimulating factor 1

1

20

High-throughput

0.439

High

126900

GELS
Gelsolin

1

0

Small-scale

0.426

High

126945

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

3131

A0A0S2Z4D7
NCK adaptor protein 1 isoform 2

1

20

High-throughput

0.417

High

126906

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024