Protein: EFS
Embryonal Fyn-associated substrate (hEFS) (Cas scaffolding protein family member 3)

Gene: EFS
Organism: Homo sapiens
Interactions: 42
UniProt ID: O43281

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007155 - cell adhesion
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

199497

FYN
Tyrosine-protein kinase Fyn

5

20

Small-scale

0.931

High

199508

BLK
Tyrosine-protein kinase Blk

5

20

High-throughput

0.930

High

199493

SRBS2
Sorbin and SH3 domain-containing protein 2

3

20

High-throughput

0.871

High

199521

OSTF1
Osteoclast-stimulating factor 1

2

20

High-throughput

0.817

High

199500

SRC
Proto-oncogene tyrosine-protein kinase Src

2

20

Small-scale

0.785

High

199498

YES
Tyrosine-protein kinase Yes

2

20

High-throughput

0.783

High

199520

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

2

18

High-throughput

0.783

High

199507

CRK
Adapter molecule crk

2

20

Small-scale

0.768

High

199489

NCK2
Cytoplasmic protein NCK2

2

20

High-throughput

0.743

High

199526

ABI2
Abl interactor 2

5

17

High-throughput

0.722

High

199516

SH2D3
SH2 domain-containing protein 3C

2

20

High-throughput

0.702

High

199519

SH3R2
E3 ubiquitin-protein ligase SH3RF2

2

20

High-throughput

0.700

High

199490

VINEX
Vinexin

1

20

High-throughput

0.698

High

199509

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

15

High-throughput

0.698

High

199525

TSSK1
Testis-specific serine/threonine-protein kinase 1

3

3

High-throughput

0.675

High

199499

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.647

High

199492

TPC6A
Trafficking protein particle complex subunit 6A

3

0

High-throughput

0.639

High

199495

ABL1
Tyrosine-protein kinase ABL1

1

20

High-throughput

0.618

High

199512

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

1

High-throughput

0.606

High

199501

NCK1
SH2/SH3 adapter protein NCK1

2

20

High-throughput

0.586

High

199502

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.586

High

199522

GLMN
Glomulin

2

0

High-throughput

0.580

High

199494

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

9

High-throughput

0.553

High

199504

AGT1
Alanine--glyoxylate aminotransferase

2

1

High-throughput

0.553

High

199513

LHX8
LIM/homeobox protein Lhx8

2

12

High-throughput

0.553

High

199503

NF1
Neurofibromin

1

7

High-throughput

0.541

High

199506

BKRB2
B2 bradykinin receptor

1

1

High-throughput

0.541

High

199491

NU155
Nuclear pore complex protein Nup155

1

2

High-throughput

0.523

High

199527

NLGN3
Neuroligin-3

1

2

Small-scale

0.508

High

199496

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

199511

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

12

Small-scale

0.501

High

199524

NPAS2
Neuronal PAS domain-containing protein 2

1

2

High-throughput

0.494

High

199505

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

16

High-throughput

0.479

High

199510

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.479

High

199514

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

3145

A0A0S2Z4E4
NCK adaptor protein 1 isoform 3

1

20

High-throughput

0.457

High

199523

LYST
Lysosomal-trafficking regulator

1

4

Small-scale

0.439

High

3132

A0A0S2Z4D7
NCK adaptor protein 1 isoform 2

1

20

High-throughput

0.417

High

91474

E7ERP6
NCK adaptor protein 2

1

20

High-throughput

0.417

High

199515

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.316

High

199518

MYOZ3
Myozenin-3

2

0

High-throughput

0.316

High

199517

ZN417
Zinc finger protein 417

1

0

High-throughput

0.299

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024