Protein: UIMC1
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)

Gene: UIMC1
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q96RL1

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair
GO:0006302 - double-strand break repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476235

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

24

2

Small-scale

0.990

High

872200

RD23A
UV excision repair protein RAD23 homolog A

3

1

Small-scale

0.843

High

1165686

ABRX1
BRCA1-A complex subunit Abraxas 1

20

1

Small-scale

0.766

High

749796

BRCA1
Breast cancer type 1 susceptibility protein

17

1

Small-scale

0.764

High

805554

BRCC3
Lys-63-specific deubiquitinase BRCC36

13

0

Small-scale

0.728

High

1301050

BABA1
BRISC and BRCA1-A complex member 1

9

0

Small-scale

0.722

High

1301052

BABA2
BRISC and BRCA1-A complex member 2

8

0

Small-scale

0.717

High

902723

SUMO2
Small ubiquitin-related modifier 2

4

1

Small-scale

0.692

High

1056945

MDC1
Mediator of DNA damage checkpoint protein 1

4

2

Small-scale

0.692

High

370252

ESR1
Estrogen receptor

3

1

Small-scale

0.665

High

228428

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.665

High

475148

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

Small-scale

0.647

High

151147

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

0

High-throughput

0.630

High

415031

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.614

High

990253

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

2

0

Small-scale

0.605

High

1301051

COMD8
COMM domain-containing protein 8

2

0

High-throughput

0.602

High

1301043

TRAIP
E3 ubiquitin-protein ligase TRAIP

2

0

Small-scale

0.598

High

387340

P53
Cellular tumor antigen p53

2

0

Small-scale

0.598

High

1273572

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

2

0

Small-scale

0.598

High

1216326

RIOX2
Ribosomal oxygenase 2

2

0

High-throughput

0.585

High

455776

PARP1
Poly [ADP-ribose] polymerase 1

2

1

Small-scale

0.584

High

918623

H2B1C
Histone H2B type 1-C/E/F/G/I

2

1

High-throughput

0.584

High

935144

H31
Histone H3.1

2

1

High-throughput

0.584

High

1301040

BARD1
BRCA1-associated RING domain protein 1

2

0

Small-scale

0.576

High

1087086

H2A2C
Histone H2A type 2-C

2

0

Small-scale

0.569

High

174428

FANCG
Fanconi anemia group G protein

1

0

Small-scale

0.554

High

1051247

ZMYM3
Zinc finger MYM-type protein 3

1

0

High-throughput

0.537

High

734999

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

2

High-throughput

0.536

High

1030429

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.515

High

1039436

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

1

High-throughput

0.515

High

1063110

ABRX2
BRISC complex subunit Abraxas 2

1

1

High-throughput

0.515

High

1119037

AMOT
Angiomotin

1

1

High-throughput

0.515

High

1252660

UBA3
NEDD8-activating enzyme E1 catalytic subunit

1

1

High-throughput

0.515

High

609688

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

0

High-throughput

0.513

High

805769

RL27A
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

1045667

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

1301039

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.513

High

1073361

NR6A1
Nuclear receptor subfamily 6 group A member 1

1

2

Small-scale

0.501

High

166450

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.493

High

216085

NRDC
Nardilysin

1

0

High-throughput

0.493

High

363883

ALBU
Albumin

1

0

High-throughput

0.493

High

590217

CCNA2
Cyclin-A2

1

0

High-throughput

0.493

High

722024

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.493

High

739245

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.493

High

867634

BLM
RecQ-like DNA helicase BLM

1

0

Small-scale

0.493

High

897296

CSN2
COP9 signalosome complex subunit 2

1

0

High-throughput

0.493

High

1251230

WDR48
WD repeat-containing protein 48

1

0

High-throughput

0.493

High

1301041

CPNE1
Copine-1

1

0

High-throughput

0.493

High

1301044

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.493

High

1301047

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

High-throughput

0.493

High

1301054

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

1301056

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.493

High

1301057

SPAT2
Spermatogenesis-associated protein 2

1

0

High-throughput

0.493

High

742481

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

1301059

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

521387

SKIL
Ski-like protein

1

0

High-throughput

0.486

High

1301048

AT8A2
Phospholipid-transporting ATPase IB

1

0

Small-scale

0.480

High

928173

SUMO1
Small ubiquitin-related modifier 1

1

1

Small-scale

0.479

High

952568

H33
Histone H3.3

1

1

High-throughput

0.479

High

1019092

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1087354

H2B2E
Histone H2B type 2-E

1

1

Small-scale

0.479

High

1173212

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.479

High

1269414

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1301049

LIN7C
Protein lin-7 homolog C

1

1

High-throughput

0.470

High

1301058

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.470

High

1139425

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

Small-scale

0.460

High

1270767

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

1282374

WBP2
WW domain-binding protein 2

1

0

Small-scale

0.460

High

160726

AURKA
Aurora kinase A

1

0

High-throughput

0.458

High

244817

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

553488

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

652014

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

658551

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

668919

PML
Protein PML

1

0

High-throughput

0.458

High

714369

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

721215

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

737993

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

High-throughput

0.458

High

913701

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

916785

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.458

High

917781

H4
Histone H4

1

0

High-throughput

0.458

High

941335

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

962927

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

1027208

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1042339

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1064055

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1188748

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1200593

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1221663

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1301046

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1301053

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1301055

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

930361

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.457

High

1301045

IN80B
INO80 complex subunit B

1

0

High-throughput

0.438

High

78249

B5MD87
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.437

High

1121426

P5CR3
Pyrroline-5-carboxylate reductase 3

1

1

High-throughput

0.437

High

1224483

Q8IZK2
Breast and ovarian cancer susceptibility protein

1

1

High-throughput

0.437

High

170563

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

1

0

High-throughput

0.279

Low

661402

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1156926

CDPF1
Cysteine-rich DPF motif domain-containing protein 1

1

0

High-throughput

0.279

Low

159254

CSKP
Peripheral plasma membrane protein CASK

1

0

High-throughput

0.269

Low

444288

FA7
Coagulation factor VII

1

0

High-throughput

0.269

Low

813690

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.269

Low

857199

CAZA1
F-actin-capping protein subunit alpha-1

1

0

High-throughput

0.269

Low

1223439

THNS1
Threonine synthase-like 1

1

0

High-throughput

0.269

Low

1301042

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.269

Low

1051422

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.268

Low

1163808

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1171328

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1079774

EREP1
Endosomal transmembrane epsin interactor 1

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024