Protein: HOOK2
Protein Hook homolog 2 (h-hook2) (hHK2)

Gene: HOOK2
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q96ED9

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005802 - trans-Golgi network
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005874 - microtubule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1289526

HOOK2
Protein Hook homolog 2

3

17

Small-scale

0.843

High

1289557

AKTIP
AKT-interacting protein

10

4

Small-scale

0.758

High

1202437

HOOK3
Protein Hook homolog 3

1

17

Small-scale

0.713

High

1289575

HOOK1
Protein Hook homolog 1

1

18

Small-scale

0.713

High

1071141

RBP1
RalA-binding protein 1

5

13

High-throughput

0.713

High

1289547

AP1M1
AP-1 complex subunit mu-1

4

8

Small-scale

0.700

High

1289579

TN13B
Tumor necrosis factor ligand superfamily member 13B

4

2

High-throughput

0.699

High

1135786

UT14C
U3 small nucleolar RNA-associated protein 14 homolog C

4

4

High-throughput

0.683

High

271167

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

3

16

High-throughput

0.667

High

826480

FNTB
Protein farnesyltransferase subunit beta

3

2

High-throughput

0.667

High

848928

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

3

High-throughput

0.667

High

203759

SUV91
Histone-lysine N-methyltransferase SUV39H1

4

1

High-throughput

0.642

High

1104074

P3H1
Prolyl 3-hydroxylase 1

2

1

High-throughput

0.628

High

1238942

POC5
Centrosomal protein POC5

2

3

High-throughput

0.628

High

1103237

C19L2
CWF19-like protein 2

3

2

High-throughput

0.616

High

1120628

ZC21C
Zinc finger C2HC domain-containing protein 1C

3

1

High-throughput

0.616

High

549209

ZN250
Zinc finger protein 250

3

1

High-throughput

0.609

High

1265335

SIA8A
Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase

3

2

High-throughput

0.609

High

1289545

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

2

5

High-throughput

0.608

High

201500

FGF16
Fibroblast growth factor 16

2

1

High-throughput

0.606

High

380667

K2C1
Keratin, type II cytoskeletal 1

2

8

High-throughput

0.606

High

447280

HXB5
Homeobox protein Hox-B5

2

6

High-throughput

0.606

High

637512

PSA1
Proteasome subunit alpha type-1

2

1

High-throughput

0.606

High

640581

DDX6
Probable ATP-dependent RNA helicase DDX6

2

3

High-throughput

0.606

High

875708

MFAP1
Microfibrillar-associated protein 1

2

1

High-throughput

0.606

High

880801

HDAC4
Histone deacetylase 4

2

19

High-throughput

0.606

High

989706

CDK18
Cyclin-dependent kinase 18

2

18

High-throughput

0.606

High

1045993

PKP1
Plakophilin-1

2

13

High-throughput

0.606

High

1047694

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

2

17

High-throughput

0.606

High

1107923

F161A
Protein FAM161A

2

4

High-throughput

0.606

High

1134927

SYT6
Synaptotagmin-6

2

3

High-throughput

0.606

High

1148027

ZFY26
Zinc finger FYVE domain-containing protein 26

2

10

High-throughput

0.606

High

1157435

PPR18
Phostensin

2

6

High-throughput

0.606

High

1241769

RN169
E3 ubiquitin-protein ligase RNF169

2

7

High-throughput

0.606

High

1246217

GA2L2
GAS2-like protein 2

2

6

High-throughput

0.606

High

1252388

LNX1
E3 ubiquitin-protein ligase LNX

2

10

High-throughput

0.606

High

1264336

MYLIP
E3 ubiquitin-protein ligase MYLIP

2

16

High-throughput

0.606

High

1289533

LRGUK
Leucine-rich repeat and guanylate kinase domain-containing protein

2

3

High-throughput

0.606

High

1289539

PKP2
Plakophilin-2

2

17

High-throughput

0.606

High

1289542

SYT17
Synaptotagmin-17

2

3

High-throughput

0.606

High

1289543

TCHP
Trichoplein keratin filament-binding protein

2

17

High-throughput

0.606

High

1289549

TSG10
Testis-specific gene 10 protein

2

18

High-throughput

0.606

High

1289552

ATG5
Autophagy protein 5

2

3

High-throughput

0.606

High

1289556

SH24A
SH2 domain-containing protein 4A

2

20

High-throughput

0.606

High

1289558

KIF9
Kinesin-like protein KIF9

2

15

High-throughput

0.606

High

1289560

NEK6
Serine/threonine-protein kinase Nek6

2

20

High-throughput

0.606

High

1289561

CABP2
Calcium-binding protein 2

2

2

High-throughput

0.606

High

1289562

PAR11
Protein mono-ADP-ribosyltransferase PARP11

2

2

High-throughput

0.606

High

1289565

AIRIM
AFG2-interacting ribosome maturation factor

2

1

High-throughput

0.606

High

1289567

RCOR3
REST corepressor 3

2

4

High-throughput

0.606

High

1289571

CYH4
Cytohesin-4

2

5

High-throughput

0.606

High

1289574

RABX5
Rab5 GDP/GTP exchange factor

2

4

High-throughput

0.606

High

1289580

TBC30
TBC1 domain family member 30

2

3

High-throughput

0.606

High

1289582

IPP
Actin-binding protein IPP

2

5

High-throughput

0.606

High

1289569

ZBT47
Zinc finger and BTB domain-containing protein 47

3

7

High-throughput

0.597

High

1235420

FHI1B
FHF complex subunit HOOK-interacting protein 1B

2

13

Small-scale

0.594

High

1164772

ANR11
Ankyrin repeat domain-containing protein 11

2

11

High-throughput

0.584

High

176837

EIF3D
Eukaryotic translation initiation factor 3 subunit D

2

0

High-throughput

0.580

High

208283

DCX
Neuronal migration protein doublecortin

2

0

High-throughput

0.580

High

344082

OAS1
2'-5'-oligoadenylate synthase 1

2

0

High-throughput

0.580

High

758307

CDN1A
Cyclin-dependent kinase inhibitor 1

2

0

High-throughput

0.580

High

1046919

BYST
Bystin

2

0

High-throughput

0.580

High

1118938

FWCH1
FLYWCH-type zinc finger-containing protein 1

2

0

High-throughput

0.580

High

1217940

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.580

High

1289527

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

1289528

CEP95
Centrosomal protein of 95 kDa

2

0

High-throughput

0.580

High

1289540

F110A
Protein FAM110A

2

0

High-throughput

0.580

High

1289550

SPC1L
Speriolin-like protein

2

0

High-throughput

0.580

High

1289551

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.580

High

551413

SIAT1
Beta-galactoside alpha-2,6-sialyltransferase 1

2

2

High-throughput

0.574

High

591237

ACM3
Muscarinic acetylcholine receptor M3

2

1

High-throughput

0.574

High

600645

EPHA1
Ephrin type-A receptor 1

2

9

High-throughput

0.574

High

1289573

DS13B
Dual specificity protein phosphatase 13B

1

10

High-throughput

0.573

High

1287077

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.560

High

1233318

PNKD
Probable hydrolase PNKD

2

4

High-throughput

0.558

High

532323

ZNF35
Zinc finger protein 35

2

3

High-throughput

0.553

High

874317

GEM
GTP-binding protein GEM

2

7

High-throughput

0.553

High

885008

RGS8
Regulator of G-protein signaling 8

2

4

High-throughput

0.553

High

997282

ZN844
Zinc finger protein 844

2

1

High-throughput

0.553

High

1039765

SNW1
SNW domain-containing protein 1

2

4

High-throughput

0.553

High

1110192

T10IP
Testis-specific protein 10-interacting protein

2

1

High-throughput

0.553

High

1133854

ZN648
Zinc finger protein 648

2

4

High-throughput

0.553

High

1140007

TTC23
Tetratricopeptide repeat protein 23

2

2

High-throughput

0.553

High

1158946

ZFP1
Zinc finger protein 1 homolog

2

2

High-throughput

0.553

High

1189185

ZN572
Zinc finger protein 572

2

4

High-throughput

0.553

High

1234232

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

1

High-throughput

0.553

High

1237620

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

3

High-throughput

0.553

High

1251757

ZN417
Zinc finger protein 417

2

1

High-throughput

0.553

High

1286096

LENG1
Leukocyte receptor cluster member 1

2

1

High-throughput

0.553

High

1289530

RBM41
RNA-binding protein 41

2

2

High-throughput

0.553

High

1289534

ZNF48
Zinc finger protein 48

2

1

High-throughput

0.553

High

1289535

F161B
Protein FAM161B

2

4

High-throughput

0.553

High

1289536

ZN587
Zinc finger protein 587

2

1

High-throughput

0.553

High

1289559

CBX8
Chromobox protein homolog 8

2

2

High-throughput

0.553

High

1289563

TB22B
TBC1 domain family member 22B

2

3

High-throughput

0.553

High

1289581

ZN835
Zinc finger protein 835

2

3

High-throughput

0.553

High

1273027

BAD
Bcl2-associated agonist of cell death

2

0

High-throughput

0.547

High

1289584

X5D778
Ankyrin repeat domain 11 isoform A

2

12

High-throughput

0.544

High

150612

ABLM1
Actin-binding LIM protein 1

1

7

High-throughput

0.541

High

309729

KAT7
Histone acetyltransferase KAT7

1

2

High-throughput

0.541

High

1060589

ZN638
Zinc finger protein 638

1

1

High-throughput

0.541

High

1267516

TSC1
Hamartin

1

20

High-throughput

0.541

High

1289568

APEX2
DNA-(apurinic or apyrimidinic site) endonuclease 2

1

1

High-throughput

0.541

High

207089

XRCC3
DNA repair protein XRCC3

1

5

High-throughput

0.536

High

895707

CXCR4
C-X-C chemokine receptor type 4

1

5

High-throughput

0.536

High

957908

EFNB1
Ephrin-B1

1

6

High-throughput

0.536

High

1016739

CETN1
Centrin-1

1

3

High-throughput

0.536

High

1077069

MARE1
Microtubule-associated protein RP/EB family member 1

1

8

High-throughput

0.536

High

1234526

LRA25
Leucine repeat adapter protein 25

1

1

High-throughput

0.536

High

1289548

UBXN6
UBX domain-containing protein 6

1

3

High-throughput

0.536

High

1289576

AP4E1
AP-4 complex subunit epsilon-1

1

11

Small-scale

0.536

High

329183

F107A
Actin-associated protein FAM107A

1

0

High-throughput

0.518

High

1017204

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.518

High

245731

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

119727

AP4M1
AP-4 complex subunit mu-1

1

8

Small-scale

0.508

High

419021

TPM3
Tropomyosin alpha-3 chain

1

15

High-throughput

0.508

High

1139932

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

13

High-throughput

0.506

High

1201247

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

13

High-throughput

0.506

High

1020390

EPS8
Epidermal growth factor receptor kinase substrate 8

1

8

High-throughput

0.494

High

1153104

IQCE
IQ domain-containing protein E

1

15

High-throughput

0.494

High

126636

P2Y10
Putative P2Y purinoceptor 10

1

8

High-throughput

0.489

High

876179

PAR2
Proteinase-activated receptor 2

1

8

High-throughput

0.489

High

1031044

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.489

High

1166527

BTNL9
Butyrophilin-like protein 9

1

6

High-throughput

0.489

High

1202526

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

1

High-throughput

0.489

High

1202706

P2RY8
P2Y purinoceptor 8

1

7

High-throughput

0.489

High

1217372

CNGA4
Cyclic nucleotide-gated channel alpha-4

1

7

High-throughput

0.489

High

1224864

FAM9B
Protein FAM9B

1

1

High-throughput

0.489

High

1230655

KT222
Keratin-like protein KRT222

1

20

High-throughput

0.489

High

1232947

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

3

High-throughput

0.489

High

1289532

F167A
Protein FAM167A

1

3

High-throughput

0.489

High

1289538

NPAS1
Neuronal PAS domain-containing protein 1

1

13

High-throughput

0.489

High

1289531

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

0

High-throughput

0.486

High

1075156

TCEA2
Transcription elongation factor A protein 2

1

3

High-throughput

0.481

High

1254472

CCHCR
Coiled-coil alpha-helical rod protein 1

1

15

High-throughput

0.481

High

1287460

AP2M1
AP-2 complex subunit mu

1

8

Small-scale

0.481

High

1289566

ITSN2
Intersectin-2

1

14

High-throughput

0.481

High

1289578

RNF6
E3 ubiquitin-protein ligase RNF6

1

6

High-throughput

0.481

High

1162368

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

Small-scale

0.480

High

163125

XPO1
Exportin-1

1

2

High-throughput

0.479

High

338826

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.479

High

833156

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

9

Small-scale

0.479

High

1042253

CUL3
Cullin-3

1

14

High-throughput

0.479

High

1284608

VP33A
Vacuolar protein sorting-associated protein 33A

1

5

High-throughput

0.479

High

1289544

CP250
Centrosome-associated protein CEP250

1

17

High-throughput

0.479

High

1289553

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

2

Small-scale

0.479

High

1289570

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

92831

E9PSE9
Coiled-coil domain containing 198

1

1

High-throughput

0.470

High

997533

Q08E77
UTP14, U3 small nucleolar ribonucleoprotein, homolog C

1

4

High-throughput

0.470

High

1289529

A26L1
Putative ankyrin repeat domain-containing protein 26-like 1

1

1

High-throughput

0.470

High

1289554

KLK15
Kallikrein-15

1

2

High-throughput

0.464

High

1266469

PSMF1
Proteasome inhibitor PI31 subunit

1

0

High-throughput

0.460

High

3181

A0A0S2Z4G9
Ring finger protein 6 isoform 2

1

1

High-throughput

0.457

High

529542

CFTR
Cystic fibrosis transmembrane conductance regulator

1

14

High-throughput

0.445

High

985761

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

13

High-throughput

0.445

High

1289564

FAME
Factor associated with metabolism and energy

1

1

High-throughput

0.439

High

402339

JUN
Transcription factor Jun

1

5

High-throughput

0.437

High

1201259

MGDP1
Magnesium-dependent phosphatase 1

1

1

High-throughput

0.437

High

1091156

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

5

High-throughput

0.407

High

793140

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

0

High-throughput

0.347

High

1188176

KANL1
KAT8 regulatory NSL complex subunit 1

2

0

High-throughput

0.334

High

1237308

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

474635

PRR35
Proline-rich protein 35

2

0

High-throughput

0.316

High

1078452

MPPD2
Metallophosphoesterase MPPED2

2

0

High-throughput

0.316

High

1135061

PPR26
Protein phosphatase 1 regulatory subunit 26

2

0

High-throughput

0.316

High

1161277

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.316

High

1169383

ZN497
Zinc finger protein 497

2

0

High-throughput

0.316

High

1205601

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1262977

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

High-throughput

0.316

High

1272850

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

1289537

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

1289546

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.316

High

1289572

ZN107
Zinc finger protein 107

2

0

High-throughput

0.316

High

1289577

FA50B
Protein FAM50B

2

0

High-throughput

0.316

High

1235102

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.304

High

1172616

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.282

High

1184694

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.282

High

1289541

PIMRE
Protein PIMREG

1

0

High-throughput

0.282

High

1289555

RIBC2
RIB43A-like with coiled-coils protein 2

1

0

High-throughput

0.282

High

50214

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.279

Low

315938

NPTXR
Neuronal pentraxin receptor

1

0

High-throughput

0.279

Low

1289583

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024