Protein: CARD9
Caspase recruitment domain-containing protein 9 (hCARD9)

Gene: CARD9
Organism: Homo sapiens
Interactions: 187
UniProt ID: Q9H257

Gene Ontology (top 5):
GO:0001819 - positive regulation of cytokine production
GO:0002446 - neutrophil mediated immunity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

330286

BCL10
B-cell lymphoma/leukemia 10

6

6

Small-scale

0.945

High

1329047

CARD9
Caspase recruitment domain-containing protein 9

5

17

Small-scale

0.928

High

1314848

CAR10
Caspase recruitment domain-containing protein 10

2

8

High-throughput

0.783

High

1329053

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

2

1

Small-scale

0.754

High

1329051

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

0

High-throughput

0.742

High

1313760

TRI62
E3 ubiquitin-protein ligase TRIM62

4

6

Small-scale

0.708

High

1157449

PPR18
Phostensin

4

4

High-throughput

0.698

High

1189195

ZN572
Zinc finger protein 572

4

3

High-throughput

0.698

High

1329064

PAK5
Serine/threonine-protein kinase PAK 5

4

17

High-throughput

0.698

High

1329080

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

3

15

Small-scale

0.680

High

549230

ZN250
Zinc finger protein 250

3

2

High-throughput

0.675

High

1139087

TASO2
Protein TASOR 2

3

6

High-throughput

0.675

High

1236839

ZN655
Zinc finger protein 655

3

5

High-throughput

0.675

High

1302374

ZN587
Zinc finger protein 587

3

5

High-throughput

0.675

High

1329065

TFP11
Tuftelin-interacting protein 11

3

1

High-throughput

0.675

High

1329070

DS13B
Dual specificity protein phosphatase 13B

3

7

High-throughput

0.675

High

1329079

AMOL2
Angiomotin-like protein 2

3

18

High-throughput

0.675

High

1302328

CK5P2
CDK5 regulatory subunit-associated protein 2

3

17

High-throughput

0.667

High

473715

ZN688
Zinc finger protein 688

3

12

High-throughput

0.654

High

880323

TCL1A
T-cell leukemia/lymphoma protein 1A

3

0

High-throughput

0.646

High

1107944

F161A
Protein FAM161A

4

1

High-throughput

0.637

High

838266

MEOX2
Homeobox protein MOX-2

2

3

High-throughput

0.633

High

1233366

SESQ1
Sesquipedalian-1

2

13

High-throughput

0.628

High

444476

K1C19
Keratin, type I cytoskeletal 19

2

10

High-throughput

0.628

High

734770

TRI23
E3 ubiquitin-protein ligase TRIM23

2

3

High-throughput

0.628

High

1254505

CCHCR
Coiled-coil alpha-helical rod protein 1

2

17

High-throughput

0.628

High

1329073

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

1

High-throughput

0.625

High

1292554

CDA7L
Cell division cycle-associated 7-like protein

2

0

High-throughput

0.618

High

201827

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

5

Small-scale

0.618

High

875740

MFAP1
Microfibrillar-associated protein 1

3

1

High-throughput

0.616

High

1103258

C19L2
CWF19-like protein 2

3

1

High-throughput

0.616

High

1237641

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

3

2

High-throughput

0.616

High

1286111

LENG1
Leukocyte receptor cluster member 1

3

1

High-throughput

0.616

High

1145927

CP135
Centrosomal protein of 135 kDa

2

16

High-throughput

0.611

High

934467

CSK21
Casein kinase II subunit alpha

1

14

Small-scale

0.608

High

61876

CC88B
Coiled-coil domain-containing protein 88B

2

18

High-throughput

0.606

High

271192

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

14

High-throughput

0.606

High

318885

K2C75
Keratin, type II cytoskeletal 75

2

3

High-throughput

0.606

High

330134

DRC4
Dynein regulatory complex subunit 4

2

1

High-throughput

0.606

High

433472

YES
Tyrosine-protein kinase Yes

2

12

High-throughput

0.606

High

445121

K1C16
Keratin, type I cytoskeletal 16

2

10

High-throughput

0.606

High

447292

HXB5
Homeobox protein Hox-B5

2

3

High-throughput

0.606

High

563382

ZNF19
Zinc finger protein 19

2

4

High-throughput

0.606

High

563433

ZNF20
Zinc finger protein 20

2

6

High-throughput

0.606

High

580103

K1C15
Keratin, type I cytoskeletal 15

2

8

High-throughput

0.606

High

638195

PSA4
Proteasome subunit alpha type-4

2

3

High-throughput

0.606

High

757758

IF4A3
Eukaryotic initiation factor 4A-III

2

2

High-throughput

0.606

High

874333

GEM
GTP-binding protein GEM

2

3

High-throughput

0.606

High

885483

ZN121
Zinc finger protein 121

2

6

High-throughput

0.606

High

984024

ZBT16
Zinc finger and BTB domain-containing protein 16

2

6

High-throughput

0.606

High

1049146

TRI14
Tripartite motif-containing protein 14

2

10

High-throughput

0.606

High

1082981

CDC37
Hsp90 co-chaperone Cdc37

2

1

High-throughput

0.606

High

1108452

ZN829
Zinc finger protein 829

2

6

High-throughput

0.606

High

1115401

USH1G
pre-mRNA splicing regulator USH1G

2

7

High-throughput

0.606

High

1144775

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

9

High-throughput

0.606

High

1154174

KRA57
Keratin-associated protein 5-7

2

6

High-throughput

0.606

High

1157040

ZN774
Zinc finger protein 774

2

6

High-throughput

0.606

High

1169353

ZN620
Zinc finger protein 620

2

5

High-throughput

0.606

High

1223081

CCD13
Coiled-coil domain-containing protein 13

2

17

High-throughput

0.606

High

1225002

TENS4
Tensin-4

2

1

High-throughput

0.606

High

1234252

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

1

High-throughput

0.606

High

1251462

LMO3
LIM domain only protein 3

2

4

High-throughput

0.606

High

1252470

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.606

High

1307375

PKP2
Plakophilin-2

2

8

High-throughput

0.606

High

1313340

ZN426
Zinc finger protein 426

2

7

High-throughput

0.606

High

1314674

SCNM1
Sodium channel modifier 1

2

1

High-throughput

0.606

High

1329050

MT21D
Protein N-lysine methyltransferase METTL21D

2

3

High-throughput

0.606

High

1329055

CABP2
Calcium-binding protein 2

2

2

High-throughput

0.606

High

1329058

DISC1
Disrupted in schizophrenia 1 protein

2

5

High-throughput

0.606

High

1329068

ZRAN1
Ubiquitin thioesterase ZRANB1

2

9

High-throughput

0.606

High

1329072

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

20

High-throughput

0.606

High

1329074

IKZF3
Zinc finger protein Aiolos

2

4

High-throughput

0.606

High

1329077

LZTS1
Leucine zipper putative tumor suppressor 1

2

19

High-throughput

0.606

High

1329078

ADIP
Afadin- and alpha-actinin-binding protein

2

0

High-throughput

0.606

High

474683

GSTT2
Glutathione S-transferase theta-2B

2

0

High-throughput

0.602

High

1329069

ENOPH
Enolase-phosphatase E1

2

0

High-throughput

0.602

High

1290988

EDC3
Enhancer of mRNA-decapping protein 3

2

0

High-throughput

0.585

High

146865

CDKA1
Cyclin-dependent kinase 2-associated protein 1

2

0

High-throughput

0.580

High

253186

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1120644

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.580

High

1242229

SLAI1
SLAIN motif-containing protein 1

2

0

High-throughput

0.580

High

1290753

MCRS1
Microspherule protein 1

2

0

High-throughput

0.580

High

1293269

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1318747

IN80B
INO80 complex subunit B

2

0

High-throughput

0.580

High

1329057

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1329062

STMN3
Stathmin-3

2

0

High-throughput

0.580

High

993598

TLE5
TLE family member 5

2

4

High-throughput

0.573

High

150623

ABLM1
Actin-binding LIM protein 1

1

6

High-throughput

0.573

High

269486

STX11
Syntaxin-11

1

5

High-throughput

0.573

High

638575

RBTN1
Rhombotin-1

1

4

High-throughput

0.573

High

928193

SUMO1
Small ubiquitin-related modifier 1

1

1

High-throughput

0.573

High

1045941

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

6

High-throughput

0.573

High

1071389

K1H1
Keratin, type I cuticular Ha1

1

15

High-throughput

0.573

High

1149344

K1C40
Keratin, type I cytoskeletal 40

1

15

High-throughput

0.573

High

1156059

HMBX1
Homeobox-containing protein 1

1

2

High-throughput

0.573

High

1183894

KCTD9
BTB/POZ domain-containing protein KCTD9

1

4

High-throughput

0.573

High

1251785

ZN417
Zinc finger protein 417

1

6

High-throughput

0.573

High

1310135

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.573

High

1317438

TRI54
Tripartite motif-containing protein 54

1

17

High-throughput

0.573

High

1329067

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.573

High

151190

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

7

High-throughput

0.560

High

1159805

NFRKB
Nuclear factor related to kappa-B-binding protein

2

1

High-throughput

0.558

High

772159

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.554

High

1127583

EFHC2
EF-hand domain-containing family member C2

2

1

High-throughput

0.553

High

1298333

F161B
Protein FAM161B

2

1

High-throughput

0.553

High

1305375

PRP18
Pre-mRNA-splicing factor 18

2

1

High-throughput

0.553

High

1313779

KIFC3
Kinesin-like protein KIFC3

2

3

High-throughput

0.553

High

1329054

CBX8
Chromobox protein homolog 8

2

2

High-throughput

0.553

High

1329059

FX4L1
Forkhead box protein D4-like 1

2

4

High-throughput

0.553

High

1329061

RBAK
RB-associated KRAB zinc finger protein

2

2

High-throughput

0.553

High

237314

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.549

High

1062330

RTP5
Receptor-transporting protein 5

1

0

High-throughput

0.549

High

1191792

NECA2
N-terminal EF-hand calcium-binding protein 2

1

0

High-throughput

0.549

High

1223821

CE57L
Centrosomal protein CEP57L1

1

0

High-throughput

0.549

High

1232770

ZCHC7
Zinc finger CCHC domain-containing protein 7

1

0

High-throughput

0.549

High

1245777

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.549

High

1304871

TSNAX
Translin-associated protein X

1

0

High-throughput

0.549

High

1329048

GO45
Golgin-45

1

0

High-throughput

0.549

High

1329075

ASC
Apoptosis-associated speck-like protein containing a CARD

1

0

Small-scale

0.546

High

170716

AXIN1
Axin-1

1

6

High-throughput

0.541

High

49763

BICL2
BICD family-like cargo adapter 2

1

18

High-throughput

0.536

High

441829

FGF4
Fibroblast growth factor 4

1

1

High-throughput

0.536

High

679394

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

5

High-throughput

0.536

High

907516

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

1002066

ARL16
ADP-ribosylation factor-like protein 16

1

9

High-throughput

0.536

High

1104180

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

2

High-throughput

0.536

High

1261047

SNX33
Sorting nexin-33

1

2

High-throughput

0.536

High

1307566

AKAP9
A-kinase anchor protein 9

1

19

High-throughput

0.536

High

773140

PBX2
Pre-B-cell leukemia transcription factor 2

1

2

High-throughput

0.523

High

1048798

TRI29
Tripartite motif-containing protein 29

1

8

High-throughput

0.523

High

1219914

TRI42
Tripartite motif-containing protein 42

1

20

High-throughput

0.523

High

1220890

PHC2
Polyhomeotic-like protein 2

1

1

High-throughput

0.523

High

1299828

PNMA5
Paraneoplastic antigen-like protein 5

1

4

High-throughput

0.523

High

1329049

F124B
Protein FAM124B

1

1

High-throughput

0.523

High

1079292

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.518

High

1272030

RAD50
DNA repair protein RAD50

1

16

Small-scale

0.515

High

66734

A8K932
Kinesin-like protein

1

10

High-throughput

0.515

High

889124

KR105
Keratin-associated protein 10-5

1

6

High-throughput

0.515

High

1271961

KLK6
Kallikrein-6

1

1

High-throughput

0.515

High

1295647

MY15B
Unconventional myosin-XVB

1

17

High-throughput

0.515

High

1329063

ZN224
Zinc finger protein 224

1

1

High-throughput

0.515

High

984439

EF1A2
Elongation factor 1-alpha 2

1

0

High-throughput

0.513

High

1132624

THEM4
Acyl-coenzyme A thioesterase THEM4

1

0

High-throughput

0.513

High

1190717

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

1138628

OTUD1
OTU domain-containing protein 1

1

1

Small-scale

0.512

High

1153109

IQCE
IQ domain-containing protein E

1

17

High-throughput

0.494

High

1287657

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.493

High

888774

KR101
Keratin-associated protein 10-1

1

6

High-throughput

0.481

High

888991

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.481

High

930384

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.481

High

1264110

PIBF1
Progesterone-induced-blocking factor 1

1

3

High-throughput

0.481

High

1329052

KIF9
Kinesin-like protein KIF9

1

9

High-throughput

0.481

High

131082

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

4

High-throughput

0.479

High

683702

1433B
14-3-3 protein beta/alpha

1

20

Small-scale

0.479

High

67341

CRTP1
Cysteine-rich tail protein 1

1

1

High-throughput

0.470

High

1116736

Q4G0R1
PIBF1 protein

1

3

High-throughput

0.470

High

1122107

Q548N1
Vacuolar protein sorting-associated protein 28 homolog

1

1

High-throughput

0.470

High

1151232

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.470

High

1183308

Q7KZS0
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.470

High

528185

CY24A
Cytochrome b-245 light chain

1

0

Small-scale

0.458

High

854859

GDIR2
Rho GDP-dissociation inhibitor 2

1

0

Small-scale

0.458

High

1268409

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

0

Small-scale

0.458

High

3222

A0A0S2Z4M1
Axin-1

1

6

High-throughput

0.457

High

3428

A0A0S2Z5X4
Zinc finger protein 688 isoform 4

1

6

High-throughput

0.457

High

1059366

CASP8
Caspase-8

1

2

Small-scale

0.445

High

1329066

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

10

Small-scale

0.445

High

1295535

CC136
Coiled-coil domain-containing protein 136

1

15

High-throughput

0.439

High

1222756

IHO1
Interactor of HORMAD1 protein 1

3

0

High-throughput

0.352

High

1172627

K0408
Uncharacterized protein KIAA0408

2

0

High-throughput

0.317

High

198784

CMIP4
Ciliary microtubule inner protein 4

2

0

High-throughput

0.316

High

1110208

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

1170363

SHSA6
Protein shisa-6

2

0

High-throughput

0.316

High

1198320

K1328
Protein hinderin

2

0

High-throughput

0.316

High

1205624

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

1223187

ZZZ3
ZZ-type zinc finger-containing protein 3

2

0

High-throughput

0.316

High

1223781

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.316

High

1282148

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

0

High-throughput

0.316

High

1329071

ZMYM5
Zinc finger MYM-type protein 5

2

0

High-throughput

0.316

High

1122048

CTSRT
Cation channel sperm-associated targeting subunit tau

1

0

High-throughput

0.299

High

1158754

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

1329076

FA50B
Protein FAM50B

1

0

High-throughput

0.299

High

1053819

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

1329056

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.279

Low

1200921

Q86V38
Atrophin 1

1

0

High-throughput

0.268

Low

1293353

CC120
Coiled-coil domain-containing protein 120

1

0

High-throughput

0.268

Low

1329060

SPAT6
Spermatogenesis-associated protein 6

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024