Protein: MED7
Mediator of RNA polymerase II transcription subunit 7 (hMED7) (Activator-recruited cofactor 34 kDa component) (ARC34) (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7) (RNA polymerase transcriptional regulation mediator subunit 7 homolog) (Transcriptional coactivator CRSP33)

Gene: MED7
Organism: Homo sapiens
Interactions: 80
UniProt ID: O43513

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

206645

MED10
Mediator of RNA polymerase II transcription subunit 10

10

6

Small-scale

0.975

High

206664

MED31
Mediator of RNA polymerase II transcription subunit 31

6

4

High-throughput

0.955

High

206653

MED4
Mediator of RNA polymerase II transcription subunit 4

6

1

High-throughput

0.953

High

206594

MED14
Mediator of RNA polymerase II transcription subunit 14

6

5

Small-scale

0.950

High

206619

MED21
Mediator of RNA polymerase II transcription subunit 21

6

3

Small-scale

0.950

High

206639

MED8
Mediator of RNA polymerase II transcription subunit 8

5

1

High-throughput

0.932

High

206655

MED17
Mediator of RNA polymerase II transcription subunit 17

5

1

High-throughput

0.932

High

48590

MED19
Mediator of RNA polymerase II transcription subunit 19

9

0

Small-scale

0.925

High

206597

MED26
Mediator of RNA polymerase II transcription subunit 26

7

0

Small-scale

0.921

High

206612

CDK8
Cyclin-dependent kinase 8

10

5

Small-scale

0.755

High

206657

MED29
Mediator of RNA polymerase II transcription subunit 29

6

1

High-throughput

0.738

High

206647

CDK19
Cyclin-dependent kinase 19

6

5

High-throughput

0.736

High

206659

MED13
Mediator of RNA polymerase II transcription subunit 13

6

2

Small-scale

0.735

High

206596

MED6
Mediator of RNA polymerase II transcription subunit 6

5

4

High-throughput

0.722

High

206627

MED27
Mediator of RNA polymerase II transcription subunit 27

5

1

High-throughput

0.722

High

206637

MED12
Mediator of RNA polymerase II transcription subunit 12

5

1

High-throughput

0.722

High

206646

MED18
Mediator of RNA polymerase II transcription subunit 18

5

1

High-throughput

0.722

High

206652

MED20
Mediator of RNA polymerase II transcription subunit 20

5

1

High-throughput

0.722

High

206658

MED11
Mediator of RNA polymerase II transcription subunit 11

5

1

High-throughput

0.722

High

206641

MED15
Mediator of RNA polymerase II transcription subunit 15

5

4

Small-scale

0.718

High

206656

MED9
Mediator of RNA polymerase II transcription subunit 9

7

0

Small-scale

0.717

High

206622

MED1
Mediator of RNA polymerase II transcription subunit 1

7

0

Small-scale

0.715

High

206651

MED28
Mediator of RNA polymerase II transcription subunit 28

6

0

High-throughput

0.705

High

206629

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

4

2

High-throughput

0.699

High

206631

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

4

1

High-throughput

0.699

High

206640

MED30
Mediator of RNA polymerase II transcription subunit 30

4

1

High-throughput

0.699

High

206661

MED23
Mediator of RNA polymerase II transcription subunit 23

4

1

High-throughput

0.699

High

206662

MED16
Mediator of RNA polymerase II transcription subunit 16

4

1

High-throughput

0.699

High

206605

CCNC
Cyclin-C

4

3

High-throughput

0.694

High

206606

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

High-throughput

0.691

High

206621

MED22
Mediator of RNA polymerase II transcription subunit 22

5

0

Small-scale

0.689

High

206595

MED24
Mediator of RNA polymerase II transcription subunit 24

4

0

High-throughput

0.670

High

206610

SRBP1
Sterol regulatory element-binding protein 1

2

0

Small-scale

0.592

High

206630

MED25
Mediator of RNA polymerase II transcription subunit 25

2

0

Small-scale

0.585

High

159791

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

1

High-throughput

0.577

High

198811

RFOX2
RNA binding protein fox-1 homolog 2

1

1

High-throughput

0.541

High

206603

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.536

High

206604

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

High-throughput

0.536

High

206608

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.536

High

206615

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

1

High-throughput

0.536

High

206665

RN114
E3 ubiquitin-protein ligase RNF114

1

1

High-throughput

0.536

High

206607

PML
Protein PML

1

0

High-throughput

0.518

High

206633

LZTR1
Leucine-zipper-like transcriptional regulator 1

1

0

High-throughput

0.518

High

206634

ZSCA1
Zinc finger and SCAN domain-containing protein 1

1

0

High-throughput

0.518

High

206643

RHXF2
Rhox homeobox family member 2

1

0

High-throughput

0.518

High

206649

TRI15
E3 ubiquitin-protein ligase TRIM15

1

0

High-throughput

0.518

High

206650

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.518

High

206667

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.518

High

206609

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

206614

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.513

High

206628

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.513

High

206632

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

0

High-throughput

0.513

High

206599

ESR1
Estrogen receptor

1

3

Small-scale

0.501

High

206611

HNF4A
Hepatocyte nuclear factor 4-alpha

1

3

Small-scale

0.501

High

206636

ESR2
Estrogen receptor beta

1

3

Small-scale

0.501

High

206613

FXR2
RNA-binding protein FXR2

1

0

High-throughput

0.493

High

206644

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.493

High

206648

BARH1
BarH-like 1 homeobox protein

1

0

High-throughput

0.493

High

206623

ATD3B
ATPase family AAA domain-containing protein 3B

1

1

High-throughput

0.489

High

206616

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.480

High

206617

TF65
Transcription factor p65

1

0

Small-scale

0.480

High

206660

DNM3L
DNA

1

0

Small-scale

0.480

High

206666

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

Small-scale

0.480

High

206602

VDR
Vitamin D3 receptor

1

1

Small-scale

0.479

High

206600

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

206618

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

206635

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.458

High

206642

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.458

High

73021

B4DUB1
cDNA FLJ50029, highly similar to Cell division cycle 2-like protein kinase 6

1

5

High-throughput

0.445

High

91292

E5RFK5
Cyclin-C

1

3

High-throughput

0.445

High

206638

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.439

High

206624

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

3231

A0A0S2Z4Q4
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

High-throughput

0.417

High

206654

PRDC1
Phosphoribosyltransferase domain-containing protein 1

2

0

High-throughput

0.318

High

206663

CAB39
Calcium-binding protein 39

2

0

High-throughput

0.316

High

206620

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.282

High

206626

CARL2
Capping protein, Arp2/3 and myosin-I linker protein 2

1

0

High-throughput

0.279

Low

206598

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.249

Low

206625

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

206601

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024