Protein: TRI69
E3 ubiquitin-protein ligase TRIM69 (EC 2.3.2.27) (RFP-like domain-containing protein trimless) (RING finger protein 36) (RING-type E3 ubiquitin transferase TRIM69) (Tripartite motif-containing protein 69)

Gene: TRI69, TRIM69
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q86WT6

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932949

FKB1B
Peptidyl-prolyl cis-trans isomerase FKBP1B

3

1

High-throughput

0.871

High

1203429

TRI69
E3 ubiquitin-protein ligase TRIM69

3

17

High-throughput

0.867

High

1203451

TRIM4
E3 ubiquitin-protein ligase TRIM4

2

16

High-throughput

0.811

High

1203458

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

17

High-throughput

0.783

High

795824

MAGA4
Melanoma-associated antigen 4

7

11

High-throughput

0.744

High

438959

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

4

1

High-throughput

0.698

High

1203438

HAUS1
HAUS augmin-like complex subunit 1

3

1

High-throughput

0.678

High

1197669

NEK8
Serine/threonine-protein kinase Nek8

3

5

High-throughput

0.675

High

1203445

F110A
Protein FAM110A

3

1

High-throughput

0.675

High

160077

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

3

6

High-throughput

0.667

High

1018826

SF3A3
Splicing factor 3A subunit 3

2

1

High-throughput

0.633

High

60361

POTEF
POTE ankyrin domain family member F

2

10

High-throughput

0.628

High

1203441

DTBP1
Dysbindin

2

1

High-throughput

0.628

High

1203446

FSP1
Ferroptosis suppressor protein 1

3

0

Small-scale

0.625

High

1203457

RSP14
Radial spoke head 14 homolog

3

8

High-throughput

0.616

High

281997

ANXA9
Annexin A9

2

5

High-throughput

0.612

High

874300

GEM
GTP-binding protein GEM

2

5

High-throughput

0.606

High

1107888

F161A
Protein FAM161A

2

4

High-throughput

0.606

High

1203442

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

2

High-throughput

0.606

High

1203448

BEX2
Protein BEX2

2

1

High-throughput

0.606

High

1203456

WWOX
WW domain-containing oxidoreductase

2

1

High-throughput

0.606

High

1203459

RPC10
DNA-directed RNA polymerase III subunit RPC10

2

3

High-throughput

0.606

High

895836

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.602

High

310973

SNAPN
SNARE-associated protein Snapin

2

0

High-throughput

0.602

High

621260

RIR1
Ribonucleoside-diphosphate reductase large subunit

2

0

High-throughput

0.602

High

1163349

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

0

High-throughput

0.602

High

328450

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

3

3

High-throughput

0.589

High

387032

P53
Cellular tumor antigen p53

2

6

Small-scale

0.584

High

799450

TNNT2
Troponin T, cardiac muscle

2

0

High-throughput

0.580

High

1080921

ETFD
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

2

0

High-throughput

0.580

High

1156451

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.580

High

1203452

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

High-throughput

0.580

High

1203455

STMN3
Stathmin-3

2

0

High-throughput

0.580

High

980283

K1C17
Keratin, type I cytoskeletal 17

1

11

High-throughput

0.573

High

1075689

SF01
Splicing factor 1

1

2

High-throughput

0.573

High

1145683

LAR1B
La-related protein 1B

1

3

High-throughput

0.573

High

1157414

PPR18
Phostensin

1

5

High-throughput

0.573

High

1203440

TRI44
Tripartite motif-containing protein 44

1

16

High-throughput

0.573

High

318661

EYA4
Eyes absent homolog 4

1

1

Small-scale

0.561

High

1160555

Q6P9E2
RECK protein

2

3

High-throughput

0.558

High

1103507

KLH38
Kelch-like protein 38

2

3

High-throughput

0.553

High

1161763

SYCE2
Synaptonemal complex central element protein 2

2

1

High-throughput

0.553

High

1203431

F90A1
Protein FAM90A1

2

1

High-throughput

0.553

High

1203453

BIN3
Bridging integrator 3

2

1

High-throughput

0.553

High

1203437

TRI63
E3 ubiquitin-protein ligase TRIM63

1

18

High-throughput

0.541

High

1203449

TRI54
Tripartite motif-containing protein 54

1

17

High-throughput

0.541

High

1203450

TRI55
Tripartite motif-containing protein 55

1

18

High-throughput

0.541

High

157946

KLF11
Krueppel-like factor 11

1

19

High-throughput

0.515

High

231598

KIF1B
Kinesin-like protein KIF1B

1

11

High-throughput

0.515

High

349442

RASH
GTPase HRas

1

3

High-throughput

0.515

High

360110

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

18

High-throughput

0.515

High

363833

ALBU
Albumin

1

2

High-throughput

0.515

High

535455

GFAP
Glial fibrillary acidic protein

1

10

High-throughput

0.515

High

667705

NOS3
Nitric oxide synthase 3

1

2

High-throughput

0.515

High

719533

MERL
Merlin

1

5

High-throughput

0.515

High

803622

BAG6
Large proline-rich protein BAG6

1

12

High-throughput

0.515

High

848073

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.515

High

868585

ATX1
Ataxin-1

1

1

High-throughput

0.515

High

877083

CASP6
Caspase-6

1

3

High-throughput

0.515

High

919147

RAN
GTP-binding nuclear protein Ran

1

2

High-throughput

0.515

High

1025827

TADBP
TAR DNA-binding protein 43

1

4

High-throughput

0.515

High

1093444

Q1RN33
Melanoma antigen A 4

1

11

High-throughput

0.515

High

1121069

GLE1
mRNA export factor GLE1

1

6

High-throughput

0.515

High

1158013

Q6P088
ZNF483 protein

1

10

High-throughput

0.515

High

1191431

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

5

High-throughput

0.515

High

1198491

Q86TH3
Dishevelled, dsh homolog 1

1

2

High-throughput

0.515

High

1203460

SHLB1
Endophilin-B1

1

3

High-throughput

0.515

High

395088

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

849358

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

Small-scale

0.501

High

851835

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

Small-scale

0.501

High

896481

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.501

High

908767

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

Small-scale

0.501

High

413980

GELS
Gelsolin

1

0

High-throughput

0.493

High

439389

ADH4
All-trans-retinol dehydrogenase [NAD(+)] ADH4

1

0

High-throughput

0.493

High

448130

DOPO
Dopamine beta-hydroxylase

1

0

High-throughput

0.493

High

584010

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.493

High

657953

CLAT
Choline O-acetyltransferase

1

0

High-throughput

0.493

High

674199

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.493

High

1203439

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.493

High

1203434

SNX31
Sorting nexin-31

1

1

High-throughput

0.489

High

150726

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

3

High-throughput

0.481

High

1203436

ZN483
Zinc finger protein 483

1

9

High-throughput

0.481

High

120159

TLR4
Toll-like receptor 4

1

6

Small-scale

0.479

High

179946

TLR3
Toll-like receptor 3

1

3

Small-scale

0.479

High

324481

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

567143

CXA1
Gap junction alpha-1 protein

1

4

Small-scale

0.479

High

668800

PML
Protein PML

1

20

Small-scale

0.479

High

1203454

TLR9
Toll-like receptor 9

1

3

Small-scale

0.479

High

46256

A0A1U9X8X8
Corneodesmosin

1

1

High-throughput

0.470

High

103784

G5E9A7
DM1 locus, WD repeat containing

1

7

High-throughput

0.470

High

344513

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.470

High

527581

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.470

High

609396

FGFR3
Fibroblast growth factor receptor 3

1

3

High-throughput

0.470

High

1203461

Q9Y649
GW128

1

1

High-throughput

0.470

High

66293

WASH1
WASH complex subunit 1

1

0

High-throughput

0.460

High

3247

A0A0S2Z4Q4
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

7

High-throughput

0.457

High

1074539

CDSN
Corneodesmosin

1

1

High-throughput

0.439

High

819591

INAR2
Interferon alpha/beta receptor 2

1

1

Small-scale

0.437

High

403491

AT5G1
ATP synthase F(0) complex subunit C1, mitochondrial

5

0

High-throughput

0.374

High

1161531

IYD1
Iodotyrosine deiodinase 1

2

0

High-throughput

0.341

High

1203432

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.328

High

1203435

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

2

0

High-throughput

0.328

High

1108676

MAJIN
Membrane-anchored junction protein

2

0

High-throughput

0.316

High

1203443

SMIP2
Protein SPMIP2

2

0

High-throughput

0.316

High

1203444

LYSM1
LysM and putative peptidoglycan-binding domain-containing protein 1

2

0

High-throughput

0.316

High

1203433

SYNE4
Nesprin-4

1

0

High-throughput

0.299

High

1203430

Q86WV8
TSC complex subunit 1

1

0

High-throughput

0.268

Low

1203447

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low


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Last updated: 15 Jul 2024